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Papillary thyroid cancer organoids harboring BRAFV600E mutation reveal potentially beneficial effects of BRAF inhibitor
Mitochondria
Substrate
EV
Metformin alleviates glucolipotoxicity
Network pharmacology uncovers that secoisolariciresinol diglucoside ameliorate premature ovarian insufficiency via PI3K/Akt pathway PMID 39788972
Zinc deficiency drives ferroptosis resistance by lactate production in esophageal squamous cell carcinoma PMID 38301975
Artesunate induces ferroptosis in diffuse large B
The C
Targeting Nrf2/PHKG2 axis to enhance radiosensitivity in NSCLC PMID 39169204
A pH
Novel arylalkylamine compounds exhibits potent selective antiparasitic activity against Leishmania major PMID 26410073
Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells PMID 24751361
LIN28A Human Pre
Oleoyl ethyl amide (N
Lupeol triggers oxidative stress, ferroptosis, apoptosis and restrains inflammation in nasopharyngeal carcinoma via AMPK/NF
Hesperetin alleviates PM2.5
S100A8 induces cyclophosphamide
MiR
Chinese traditional formula Kaixin San suppressed ferroptosis of hippocampal neurons and cardiomyocytes in mice with paradoxical sleep deprivation PMID 36529245
KRFK TFA
Lactobacillus gasseri LGV03
KIF4A Inhibits Ferroptosis in Glioblastoma via the CHMP4B/GPX4 Axis and Promotes Temozolomide Resistance PMID 40705827
Autologous Serum from Sjögren's Syndrome Patients Mitigates Ferroptosis in Hyperosmolarity
SENP2
Myricetin Induces Ferroptosis and Inhibits Gastric Cancer Progression by Targeting NOX4 PMID 38483540
STING activation in macrophages by vanillic acid exhibits antineoplastic potential PMID 37211172
2'
3′
NSC 328786
2,5
hydroxy
嘧啶
1
(H2IPr)(Cl)2Ru=CH(o
Astragaloside IV Pretreatment Alleviates Pulmonary Ischemia
Molecular Mechanisms of Antiviral Agents against Dengue Virus PMID 36992414
Targeting ferroptosis alleviates methionine
Somatic p53 mutations that are markedly overrepresented in lung cancer confer resistance to ROS
Ginsenoside Rb1 targets to HO
animal model
Tazobactam
11(Z),14(Z),17(Z)
cCF10
L
Mitoquinone protects against acetaminophen
NASH LOs model
Liraglutide alleviates ferroptosis in renal ischemia reperfusion injury via inhibiting macrophage extracellular trap formation PMID 39340991
Angiotensin II Induces Vascular Endothelial Dysfunction by Promoting Lipid Peroxidation
Nitidine chloride induces caspase 3/GSDME
CoCrMo
Establishment and Characterization of a Brca1
Esketamine alleviates ferroptosis
Spliceosomal GTPase Eftud2 deficiency
NSC 13138 (Cinchoninic acid (6CI,7CI,8CI))
BCAT2 binding to PCBP1 regulates the PI3K/AKT signaling pathway to inhibit autophagy
Human α
Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer PMID 34162423
Dynamic O
Intermetallics triggering pyroptosis and disulfidptosis in cancer cells promote anti
Astragali radix
GNF
Tanshinone IIA inhibits gastric cancer cell stemness through inducing ferroptosis PMID 34661962
Erastin induces ferroptosis via ferroportin
Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage PMID 38454452
Buzhong yiqi decoction improves cisplatin resistance in non
Silencing of LOX
Red blood cells undergo lytic programmed cell death involving NLRP3 PMID 40252640
Small molecule enoxacin is a cancer
DU
Comprehensive network pharmacology and experimental study to investigate the effect and mechanism of solasonine on breast carcinoma treatment PMID 39962568
ADAMTS
Cangrelor alleviates bleomycin
Inhibitory effect on α
Vinpocetine protects against osteoarthritis by inhibiting ferroptosis and extracellular matrix degradation via activation of the Nrf2/GPX4 pathway PMID 39368343
Super
Hexadecanedioic acid
ENPP
C
Botensilimab
Tixagevimab
N,N
Klk1 Mouse Pre
Clevudine triphosphate (L
(R)
CRMP1 蛋白, Human
Creatinase, Actinobacteria 37340
Ferritinophagy
Identifying disulfidptosis subtypes in hepatocellular carcinoma through machine learning and preliminary exploration of its connection with immunotherapy PMID 38831301
FXR deficiency induced ferroptosis via modulation of the CBP
(
Inhibition of ferroptosis in inflammatory macrophages alleviates intestinal injury in neonatal necrotizing enterocolitis PMID 40764334
A miniature CRISPR
Interplay between lipid dysregulation and ferroptosis in chondrocytes and the targeted therapy effect of metformin on osteoarthritis PMID 38621621
全球办事处
A translational in vitro to in vivo study on chronic arsenic exposure induced pulmonary ferroptosis and multi
The cardiac glycoside periplocymarin sensitizes gastric cancer to ferroptosis via the ATP1A1
Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models PMID 24592866
PRDM16 suppresses ferroptosis to protect against sepsis
Contribution of ferroptosis and GPX4's dual functions to osteoarthritis progression PMID 35101656
Astaxanthin alleviates PM2.5
Inhibition of ASIC1a reduces ferroptosis in rheumatoid arthritis articular chondrocytes via the p53/NRF2/SLC7A11 pathway PMID 39760183
TCF7L2 regulates GPX4 to resist ferroptosis and enhance osteogenesis in mouse mesenchymal stem cells PMID 40764595
The effect of USP17 knockdown on autophagic ferroptosis in gastric cancer by regulating the BNIP3
Redistribution of defective mitochondria
Gambogenic acid induces cell death in human osteosarcoma through altering iron metabolism, disturbing the redox balance, and activating the P53 signaling pathway PMID 37302459
Transcriptome Analysis of Norepinephrine
Targeting PDK4 to mitigate osimertinib
ADAM
Chrysin enhances sunitinib sensitivity in renal cell carcinoma by inducing ferroptosis via targeting PI3K/Akt/GPX4 pathway PMID 40848919
多肽库
OGFOD1 enables AML chemo
ADL
Astragaloside IV Improves Pulmonary Vascular Endothelial Dysfunction in Pulmonary Arterial Hypertension by Inhibiting Ferroptosis through Modulation of the Calpain
ZDHHC3
lipoxygenase 蛋白, Pseudomonas aeruginosa
TMEM16A deficiency in alveolar type 2 epithelial cells protected against endoplasmic reticulum stress
MNI137
Brusatol induces ferroptosis to inhibit hepatocellular carcinoma progression by targeting ATF3 PMID 38862254
2
Ferroptosis participates in neuron damage in experimental cerebral malaria and is partially induced by activated CD8+ T cells PMID 35725567
Loss of β
Dichloroacetate attenuates the stemness of colorectal cancer cells via trigerring ferroptosis through sequestering iron in lysosomes PMID 33166055
RSL3 induces ferroptosis by activating the NF
Induction of apoptosis and ferroptosis by a tumor suppressing magnetic field through ROS
Nanozyme as tumor energy homeostasis disruptor mediated ferroptosis for high
CDK9降解剂、基因
2
BRF110
USP24 promotes autophagy
Tanshinone IIA confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis and apoptosis via VDAC1 PMID 37800609
A new gold(I) phosphine complex induces apoptosis in prostate cancer cells by increasing reactive oxygen species PMID 38782835
Functional synapses between neurons and small cell lung cancer PMID 40931078
Gastrodin improves learning and memory in sleep
Spatially blocked split CRISPR
Indobufen inhibits tissue factor in human monocytes through a thromboxane
Betulinic Acid Inhibits Glioma Progression by Inducing Ferroptosis Through the PI3K/Akt and NRF2/HO
Ginger
Macrophages induce cardiomyocyte ferroptosis via mitochondrial transfer PMID 35933052
(±)
Lipid peroxidation triggered by the degradation of xCT contributes to gasdermin D
SLC7A11 as a therapeutic target to attenuate phthalates
Curcumin promotes ferroptosis in hepatocellular carcinoma via upregulation of ACSL4 PMID 39311951
Janelia Fluor® 669, SE (JF669, SE)
PIP4K2C
PIP4K2C
Lumiliximab (Gomiliximab，鲁昔单抗)
MiTMAB
茶碱（标准品）
Iridium(III) complexes as type I photosensitizers for hypoxic two
FA
N
Modulating ATOH1 and POU4F3 Pathways to Enhance Hair Cell Regeneration and Inhibit Ferroptosis in Cochlear Support Cells PMID 40719825
O
5
Anlotinib induced ferroptosis through the p53/xCT/GPX4 pathway in non
The Knockdown of ETV4 Inhibits the Papillary Thyroid Cancer Development by Promoting Ferroptosis Upon SLC7A11 Downregulation PMID 34283663
SIRT3 inhibits gallbladder cancer by induction of AKT
Omberacetam (GVS
Development of a radiochemical cyclooxygenase
PARP inhibitors chemopotentiate and synergize with cisplatin to inhibit bladder cancer cell survival and tumor growth PMID 35321693
The efficacy and potential mechanism of cnidium lactone to inhibit osteoclast differentiation PMID 31343277
Top Publications Citing MCE Products
Light green SF yellowish (Acid Green 5)
DSPE
Dolastatin 15 (DLS 15)
PHOP
Generation of Myeloid
Basal cell of origin resolves neuroendocrine
Gastrodin targets the system Xc
PRMT4 promotes ferroptosis to aggravate doxorubicin
Ferroptosis was more initial in cell death caused by iron overload and its underlying mechanism in Parkinson's disease PMID 32217194
Fmoc
Botulinum toxin A attenuates osteoarthritis development via inhibiting chondrocyte ferroptosis through SLC7Al1/GPX4 axis PMID 38714267
Phytochelatin 3 TFA (PC 3 TFA)
Nithiamide (Standard) (CL
Cinnamyl cinnamate (Styracin，桂酸桂酯)
Velutin
Olanzapine suppresses mPFC activity
Top Publications Citing MCE Products
L
Thalidomide
L2H2
Cedarwood terpenes
Pine Bark Extract (松树皮提取物)
UL
PH10
金缕梅单宁
Combretastatin A1 diphosphate
CLB
Surlorian
Julimycin B2 18126
(4
Tm4sf1 Rat Pre
Glyphosate
6
BCL6 蛋白, Human
Tolimidone (MLR
Tryptamine
Mrgprx2 Rat Pre
TSTD1 Human Pre
4
L
DPhPC
AUTAC Linker
DIPQUO 1269365
胆甾醇
AS013
吗多明EP杂质B
Rhodamine structure
DBPR 110
唑尼沙胺
Sodium 1
Bromocriptine
LSD1
Pyrimidin
Thalidomide
LGD1069 d<sub>4</sub>
DNP
UBA5
Antitubercular agent
1
RG 3487
Alloferon2
Di
IP
Boc
CRM1
8(S)
D
Clusterin/APOJ 蛋白, Mouse (HEK293, His)
ATP
Rab5b Mouse Pre
SOS1 activator 2
十三醇(mixture of isomers)
Methyl 2
SHR
Adenosine 5& 039;
PFK
L
TCR stimulation with modified anti
Flucythrinate
Npc1 Mouse Pre
T regulatory cell differentiation
Polymyxin D1
variant
Abemaciclib
LJ570
Aryl Hydrocarbon Receptor
Non
Competitive inhibition
Glycogen synthase 1/GYS1 抗体 (YA401)（Glycogen synthase 1/GYS1 Antibody (YA401)）
Myristoyl tetrapeptide12
PLK1
Itopride N
Propargyl
Aprt Rat Pre
Anthraquinone analog
TAMRA
Mycbp2 Rat Pre
N
NSC
m
Glut
Urtoxazumab
Lucidenic acid D 2
Maprotiline
ZL0420
依帕斯他
DHP
Neuraminidase, arthrobacter ureafaciens
Mereletinib
MMP
PAD2
resorption
Linagliptin impurity11
Measurement of pentosidine in biological samples PMID 22351277
Unique induction of p21(WAF1/CIP1)expression by vinorelbine in androgen
SKLB325 66680
drug delivery agents
Src
Nourseimycin
Slc6a3 Mouse Pre
Map2k7 Mouse Pre
PIM
MCAT Human Pre
DH
Map3k3 Mouse Pre
Rucaparib A Review in Ovarian Cancer PMID 30830551
Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel PMID 24569998
C.I. Vat Yellow 2 129
Penicillin
7
Cd33 Mouse Pre
香苹婆提取物 (Sterculia foetida Linn.)
GH/Somatotropin 蛋白, Mouse
Oleanolic acid alleviating ischemia
STAT5B Suppresses Ferroptosis by Promoting DCAF13 Transcription to Regulate p53/xCT Pathway to Promote Mantle Cell Lymphoma Progression PMID 38979130
AP
Histone lactylation stimulated upregulation of PSMD14 alleviates neuron PANoptosis through deubiquitinating PKM2 to activate PINK1
Fluid shear stress activates a targetable mechano
Study on the effect of deer bone in improving rheumatoid arthritis based on the drug
Fc gamma RIIIA/CD16a 蛋白, Human (F176V, HEK293, SUMO
MGST1 facilitates novel KRASG12D inhibitor resistance in KRASG12D
Targeting Phospholipid Metabolism as an Effective Hearing Protection Strategy PMID 40580390
(+)
Mechanosensitive genomic enhancers potentiate the cellular response to matrix stiffness PMID 40997217
A novel non
o
Hederagenin promotes lung cancer cell death by activating CHAC1
Identification of FADS2 as a Contributor of Ferroptosis Escape in Bladder Cancer PMID 40682485
Deflazacort
MCE
Oxygen Nanobubbles Enhance ICG/Fe(III)
Exoticin
二氢大叶茜草素
Stauntosaponin A (Stauntoside C)
Cancer
MMP17 Human Pre
Naltiazem 108383
Knockdown of SETD2 promotes erastin
Hydroxy ipronidazole
8
CKS2 induces autophagy
Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes PMID 32992479
Cystatin C/CST3 蛋白, Rat (HEK293, His)
Erianin triggers ferroptosis in colorectal cancer cells by facilitating the ubiquitination and degradation of GPX4 PMID 39938177
Inhibiting ACSL1
Sorafenib induces ferroptosis in human renal cell carcinoma cells through CCAT/enhancer
Intracellular C5aR1 inhibits ferroptosis in glioblastoma through METTL3
Celastrol attenuates ferroptosis
Notch3 regulates ferroptosis via ROS
Isoxadifen
Melatonin inhibits ferroptosis and delays age
BDE
Lathyrol (千金子二萜醇)
L18I
Proteomics, Transcriptomics, and Phosphoproteomics Reveal the Mechanism of Talaroconvolutin
SIK1 promotes ferroptosis resistance in pancreatic cancer via HDAC5
Berberine inhibits high glucose
Liraglutide attenuates type 2 diabetes mellitus
PTPS Facilitates Compartmentalized LTBP1 S
GLUT
非奈西林钠盐
BODIPY TMR
Choline Chloride
Cryptochrome 2 suppresses epithelial
ASP 8273
HSD17B13
Antimalarial agent 1
Tnfrsf8 Mouse Pre
美海屈林 (标准品)
DL
Cannabinoid Receptor
C
1
2,2& 039;
Quercetin 3,4′
N6
GSCs
DL
CFTR stabilizer
(E,E)
Acimtamig
Dodecyl azide (1
Cpd
Neuroprotective agent9
AZD 5363
Cep76 Mouse Pre
WiD
HC
ADAM17/PTGS2 Facilitates Pulmonary Fibrosis by Regulating Ferroptosis PMID 40077919
Akt Substrate
Osthole inhibits proliferation and induces autophagy
Neuraminidase
ICG
FITC
Epigenetic Reader Domain
Sequosempervirin D
Cephalosporin C (头孢菌素 C)
Caps Rat Pre
琥珀酸普芦卡必利
美拉酮宁
MPD2
SJG
MTH1 inhibition synergizes with ROS
ACC1/2
Aah II
Isoprenaline impurity 1 hydrochloride
Blinin
盐酸倍他司汀EP杂质C (标准品)
DMBT1 Human Pre
A novel protein encoded by circFOXP1 enhances ferroptosis and inhibits tumor recurrence in intrahepatic cholangiocarcinoma PMID 38945202
Chronic microcystin
Mal
eeAChE/eqBuChE
t
Iron
Propranolol
Thiostrepton induces oxidative stress, mitochondrial dysfunction and ferroptosis in HaCaT cells PMID 38969192
Ascomycin
Tridecane
PASMC
defects
Gap43 Mouse Pre
N
Navane
The ferroptosis inducing compounds RSL3 and ML162 are not direct inhibitors of GPX4 but of TXNRD1 PMID 37087975
Cdk14 Mouse Pre
Deoxynojirimycin tetrabenzyl ether
KMT2A Human Pre
AMX208
DCDS0780A
(R)
V1/S
YAP/TEAD
Plasma
CD4
FATP5 deficiency alleviates MASH via remodeling hepatic lipid composition to suppress ferroptosis PMID 40840619
rodin
HEB IL
5& 039;
current
Nampt
氟伐他汀
2’
Oxytocinergic input from the paraventricular nucleus to the nucleus accumbens core modulates methamphetamine
油红XO
D
(Rac)
RTC
Type VI and III secretion systems
4,10
Taltirelin
Cela2a Rat Pre
Timosaponin AIII promotes non
m
DEADbox
SRSF7 Human Pre
Nequinate
EAU model
RH
TAT
Map3k1 Rat Pre
PM2.5 exposure exacerbates seizure symptoms and cognitive dysfunction by disrupting iron metabolism and the Nrf2
Palmitoyl Tetrapeptide
NSC 8041
host DIS3L2
Rucaparib antagonize multidrug resistance in cervical cancer cells through blocking the function of ABC transporters PMID 32717310
E1
DL
NEDD4L affects KLF5 stability through ubiquitination to control ferroptosis and radiotherapy resistance in oesophageal squamous cell carcinoma PMID 39317954
DABS
STUB1 exacerbates calcium oxalate
Apoc3 Rat Pre
Ccs Rat Pre
Trim7 Mouse Pre
Isogomisin O (异戈米辛O)
5
富马酸卢帕他定
Gnetin D
N
Helenium amarum
IDN
Tirofiban 144494
Oasomycin B
异山梨醇
Modulatory role of radioprotective 105 in mitigating oxidative stress and ferroptosis via the HO
Cleavable
Moscatilin Induces Ferroptosis in Clear Cell Renal Cell Carcinoma via the JAK
Odanacatib
Rnpep Mouse Pre
Over
PLLA2000
SF3b
Exploring the molecular mechanisms through which overexpression of TET3 alleviates liver fibrosis in mice via ferroptosis in hepatic stellate cells PMID 40096933
5& 039;
Identification of Frataxin as a regulator of ferroptosis PMID 32169822
Cbl
pd
EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40
Col1a1 Rat Pre
Dermal papilla cells
suppository
Torulin
The positive feedback loop of the NAT10/Mybbp1a/p53 axis promotes cardiomyocyte ferroptosis to exacerbate cardiac I/R injury PMID 38583415
Naringenin relieves paclitaxel
Uridine
Atuzabrutinib (SAR 444727)
RB1 loss overrides PARP inhibitor sensitivity driven by RNASEH2B loss in prostate cancer PMID 35179959
Inhibition of neuronal ferroptosis in the acute phase of intracerebral hemorrhage shows long
FB1 causes barrier damage to vascular endothelial cells through ferroptosis by a PINK1/Parkin mediated mitophagy
VUF11211
A Streptococcus pneumoniae endolysin mutant protein ΔA146Ply elicits rapid broad
Neutrophil extracellular traps induce fibroblast ferroptosis via IRE1α/XBP1
PIAS3 promotes ferroptosis by regulating TXNIP via TGF
Magnaldehyde D (厚朴醛D)
Synthesis, biological evaluation, X
Targeted Manganese doped silica nano GSH
Structural Elucidation of Malonylcommunol and 6β
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