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PCSK9 promotes T helper 1 and T helper 17 cell differentiation by activating the nuclear factor
Isocitrate dehydrogenase, Microorganism (ICDH, Microorganism，异柠檬酸脱氢酶，微生物)
Blood
SCH 12223 free base 89109
Epothilone A (Standard)
Nicotinimidamide hydrochloride 7356
NC
Acetyl
ABL1 Q252H Recombinant Human Active Protein Kinase
LAG
PRKCG Human Pre
3
UHRF1(N
Tetrahydrobenzo[h]quinoline derivatives as a novel chemotype for dual antileishmanial
Retinyl acetate
Cytotoxic Hexacyclic Triterpene Acids from Euscaphis japonica PMID 20873721
R
2,5
Trenimon
Type II TRK inhibitor 1
Synthesis and biological evaluation of lovastatin
Oxypurinol
Synthesis and antiviral activities of quinazolinamine
LAG
Melatonin
GE1111
R
Suxibuzone (Standard) (琥布宗(Standard))
ABL1 Q252H Recombinant Human Active Protein Kinase
Deulorlatinib
In vitro and in vivo activities of a novel β
SPRINT a Cas13a
Peptide
cytochrome
ATG
Transcription factor networks drive perforin activity in the anti
Synthesis, antiviral activity and cytotoxicity evaluation of Schiff bases of some 2
SN
COMT 蛋白, Human (sf9, His)
LJ 570
Ercalcidiol
Discovery of novel VEGFR
EPA but not DHA appears to be responsible for the efficacy of omega
Magnesium sulfate heptahydrate, meets analytical specification of Ph. Eur. BP USP FCC
trans
Anti
Medium from human iPSC
ADG
6
Carboxyamidotriazole (Standard)
Orally delivered MK
cAC10
Epithelial Gasdermin D shapes the host
4
T338C Src
Reconstitution of the alternative pathway of the complement system enables rapid delineation of the mechanism of action of novel inhibitors PMID 38876307
Dienochlor (Decachlor，除螨灵)
MAP4K4 aggravates microvascular anomalies in diabetic retinopathy in a YTHDF2
DSM705 hydrochloride 2989908
The Role of Coagulation
程序性细胞死亡1（Pdcd1）基因
Gasdermin D is involved in switching from apoptosis to pyroptosis in TLR4
苯磺酸氨氯地平 d<sub>4</sub> (苯磺酸盐)
Polygonatum sibiricum polysaccharide ameliorates neurotoxicity in Alzheimer disease mice by inhibiting endoplasmic reticulum stress and lipid raft formation through AMPK/GSK3β/Nrf2 pathway PMID 40946159
EPZ
synthetic lethal lead
Asph Mouse Pre
Peroxisome Proliferator
C型凝集素受体
Hydroxylapatite ( 50 nm) (Hydroxyapatite ( 50 nm))
Colecalciferol
PACAP (1
Harnessing artificial intelligence to identify Bufalin as a molecular glue degrader of estrogen receptor alpha PMID 40846852
Ms
The translation inhibitor silvestrol exhibits direct anti
Epigallocatechin
Hmgn1 Mouse Pre
Wasf1 Mouse Pre
Listerin Alleviates Alzheimer's Disease through IRE1
Discovery of Lanraplenib (GS
Blonanserin C
Degrader
2,4
Brattleboro rats
Poloxamer 338 (F108) (PEG
Discovery of Spiro
(S)
SK3
hyperpigmentation disorders
XD 23
Adgrb1 Mouse Pre
反转录
Upacicalcet, a positive allosteric modulator of the calcium
CAB
双氢青蒿素
Discovery of (10R)
UK
P
缺口受体 1（NOTCH1）基因
盐酸三氟哩啶
WNT8B Human Pre
Balamapimod (MKI 833)
Potassium acetate
P60v
Ca channels
Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor PMID 36300829
Identification and functional activity of Nik related kinase (NRK) in benign hyperplastic prostate PMID 38459501
Hot shape transformation the role of PSar dehydration in stomatocyte morphogenesis PMID 39811685
1
LncRNA NBR2 inhibits tumorigenesis by regulating autophagy in hepatocellular carcinoma PMID 33378941
Cisd2 agonist 1
Nuclear receptor peroxisome proliferator
Notch Antagonists Potential Modulators of Cancer and Inflammatory Diseases PMID 27045975
Cyclic Hexapeptides from the Deep South China Sea
Valbenazine
IL
Transcriptional regulation of the human CYP3A4 gene by the constitutive androstane receptor PMID 12130689
pancreatic ductal adenocarcinomas
ML
BI
MCE
Phospholipase Ligand、基因
Survivin/BIRC5 抗体 (YA665)（Survivin/BIRC5 Antibody (YA665)）
Discovery of Clinical Development Candidate GDC
Ppif Rat Pre
ADIPOQ Human Pre
Toward establishing structure
Syntheses and biological activities of sulfoximine
Discovery of Natural Ursane
Extracellular matrix substrates differentially influence enteric glial cell homeostasis and immune reactivity PMID 39119341
FHL2 activates β
Pathways
High
Lenzilumab 1229575
Determination of bicuculline in rat plasma by liquid chromatography mass spectrometry and its application in a pharmacokinetic study PMID 24607696
Microcystin
8
CRA
Lansoprazole sulfone (AG
SLIGRL
Bioactive Triterpenoids from the Twigs of Chaenomeles sinensis PMID 28358502
Heat shock protein 90 (Hsp90)/Histone deacetylase (HDAC) dual inhibitors for the treatment of azoles
Development of Heat Shock Protein (Hsp90) Inhibitors To Combat Resistance to Tyrosine Kinase Inhibitors through Hsp90
ChEMBL22003
WCA
Small
Aldehyde oxidase 1 promotes gallbladder carcinogenesis through ROS
RG
Brompheniramine maleate (Standard)
PD
GSK376501A
LY3027788 hydrochloride
Ronidazole Is a Superior Prodrug to Metronidazole for Nitroreductase
Adcyap1r1
Metformin enhances endogenous neural stem cells proliferation, neuronal differentiation, and inhibits ferroptosis through activating AMPK pathway after spinal cord injury PMID 39103875
2,3
Porous Silicon Nanocarriers Boost the Immunomodulation of Mitochondria
EIU rabbit model
BF738735
RXR antagonist 2
细胞外信号调节激酶
Cinnamohydrazide
Biotin
Biological evaluation and structural insights for design of subtype
KW 5617
Diethylstilbestrol
Crotonic acid as a bioactive factor in carrot seeds (Daucus carota L.) PMID 15960983
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors PMID 22632936
Mechanism of CXCL8 regulation of methionine metabolism to promote angiogenesis in gliomas PMID 39488622
Carbocisteine attenuates TNF
Fcγ受体 IIa（FCGR2A）基因
11
PGK1抑制剂、基因
NSC 47462
Diaza
Trhde Mouse Pre
(2E)
EMB
层压空调（LMNA）基因
FAK
Isoharringtonine
Novel 5
age
Xylocydine
(2E,21Z,24Z,27Z,30Z,33Z)
URB937
Diarylheptanoid glycosides from Tacca plantaginea and their effects on NF
Tlr3 Mouse Pre
HY
动力精核苷
1,2
NF
PAK3 Exacerbates Cardiac Lipotoxicity via SREBP1c in Obesity Cardiomyopathy PMID 39137120
Pterostilbene inhibits melanogenesis, melanocyte dendricity and melanosome transport through cAMP/PKA/CREB pathway PMID 36038012
FITC
ATP1A3
Valericanhydride 2082
BMP1 inhibitor UK383367 improves MI
Synthesis and evaluation of novel polyaminocarboxylate
7
Salicylic acid 2
INCB16562 933768
ECS cell
TMU35435
rel
Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2 PMID 21275386
teratogenand
NND 502
Histone Deacetylase 3 Governs β
The combination of berberine and isoliquiritigenin synergistically improved adipose inflammation and obesity
Cholic acid exposure during late pregnancy causes placental dysfunction and fetal growth restriction by reactive oxygen species
SORT
Dehydrocholic acid sodium 145
VSV
FSH beta 蛋白, Human (HEK293, His)
Microglia depletion reduces human neuronal APOE4
Development of CINPA1 analogs as novel and potent inverse agonists of constitutive androstane receptor PMID 26717202
Modulatory Effect of Curcumin on Expression of Methyltransferase/Demethylase in Colon Cancer Cells Impact on wt p53, mutp53 and c
HDAC6
FNDC5/Irisin mitigates high glucose
Momelotinib sulfate (Standard)
1
A novel, dual pan
反式
Anthocyanins from purple corn activate free fatty acid
(Arg)9 acetate (Nona
CNP0296775
Endothelial cell
BDC2.5 mimotope 1040
L
Suclg2 Mouse Pre
Tetrapeptide Substrate
(2S)
P
Meteorin
格迪伏单抗
3
PSGL
EPH 受体 A1（EPHA1）基因
IL37 Human Pre
Characterization of the cellular and antitumor effects of MPI
AZD 2014
B
AQP4 蛋白, Mouse (Cell
erb
4
pancreatic B cell
Sodium cholate
Theophylline 58
PGC1 alpha 抗体 (YA5018)（PGC1 alpha Antibody (YA5018)）
Siglec1 Mouse Pre
MCE
MAPKs
Top Publications Citing MCE Products
5
Methyl L
MNAC13
RH1115
ICG PEG N3 (MW 2000)
B7
ADAM10 Human Pre
珠卡赛辛(Standard)
25
CDD 1147
Turofexorate isopropyl (Standard)
erythro
TGTX1101
PHOX2B Human Pre
DDR1 蛋白, Mouse (HEK293, Fc)
CCR5 蛋白, Human (HEK293, Flag, His, Strep)
Eosinophilic inflammation promotes CCL6
CCG
奈玛特韦
Improvement of physiochemical properties of the tetrahydroazepinoindole series of farnesoid X receptor (FXR) agonists beneficial modulation of lipids in primates PMID 20095622
2& 039;
LEE 011
LBG30300
Piezo2 Mouse Pre
L
(Rac)
Carasinol B
二氢青蒿素
(E)
Linamarin
磷酸氢二钠二水合物, meets analytical specification of Ph. Eur. BP
BMS
(R)
反式
3,4
轴心 2（AXIN2）基因
1,2
生物素化屋尘螨提取物, 来源粉尘螨
Fecal microbiota transplantation regulates the microbiota
processes
17α
MoDnm1 Dynamin Mediating Peroxisomal and Mitochondrial Fission in Complex with MoFis1 and MoMdv1 Is Important for Development of Functional Appressorium in Magnaporthe oryzae PMID 27556292
同位素标记一般有机物 (Other Isotope
E
topical
Pezulepistat
IgG1 蛋白, Human (Biotinylated, C103S, HEK293)
Pparδ agonist 2
Boc
SNAP29 Human Pre
Response to interferon
Acetylene Group, Friend or Foe in Medicinal Chemistry PMID 32031378
Halosulfuron
CD63 抗体 (YA5577)（CD63 Antibody (YA5577)）
6
Cyclosporin D (Standard) (环孢菌素D (Standard))
Pharmacological activation of SIRT6 triggers lethal autophagy in human cancer cells PMID 30250025
Pochonins A
Top Publications Citing MCE Products
17β
Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson's disease PMID 26124091
DPP
2
Ambroxol
inorganic compounds
Nitro and amino substitution in the D
PP102
Dipeptidyl peptidase 4 inhibition sensitizes radiotherapy by promoting T cell infiltration PMID 37849962
Wnt激动剂、基因
AF 594 azide triethylamine
Anti
Top Publications Citing MCE Products
(
Stearoyl chloride 112
LRRK2
Further exploration of an N
N,N
ALK 蛋白, Human (L1196M, Biotinylated, sf9, Avi)
PERK/eIF2α activator 1
Integrin调节剂、基因
Phospholipase Control、基因
Effect of oral and parenteral administration of metanil yellow on some hepatic and intestinal biochemical parameters PMID 9048233
β
TMEM41B Is an Interferon
Arachidyl myristate
Leptomycin B reduces primary and acquired resistance of gefitinib in lung cancer cells PMID 28942004
ELP
Dysregulated B7H4/JAK2/STAT3 Pathway Involves in Hypertriglyceridemia Acute Pancreatitis and Is Attenuated by Baicalin PMID 35781653
HFD
Lipase mediated new chemo
受体蛋白酪氨酸激酶
5
Anti
甲吡酮(Standard)
Kallikrein
6
YX968
adipose tissue
Antiviral Therapeutic Potential of Curcumin An Update PMID 34834089
盐酸地尔硫卓
Antitumor agent
CK1α degrader
Dehydro amlodipine fumarate (Standard)
food
1
3
Amelioration of Alzheimer's disease pathology by mitophagy inducers identified via machine learning and a cross
Emavusertib
Carbocisteine protects against emphysema induced by cigarette smoke extract in rats PMID 20847042
Unveiling a Potent Small Molecule Disruptor for RNA G
Ethybenztropine 524
Rational design, synthesis and biological evaluation of dual PARP
Bisabolene (mixture of isomers) (Bisabolene)
5
1,1& 039;
Integrin激活剂、基因
A selective, orally bioavailable 1,2,4
Nuclear Softness Promotes the Metastatic Potential of Large
Oprk1 Mouse Pre
Tab1 Mouse Pre
Ethics and cloning PMID 30203088
CALM1 Human Pre
4
PTH1R激动剂、基因
Gentisuric acid (Standard)
木防己苦毒素
Structure
Harmine produces antidepressant
Molecular cloning and characterization of the canine prostaglandin E receptor EP2 subtype PMID 10410384
ganoderma applanatum
Closantel (氯氰碘柳胺)
死亡受体
Clec12a Mouse Pre
An NR2F1
N
AcPHF
Abhd11 Mouse Pre
SART3 Human Pre
CDD 1128
Discovery of potent small molecule PROTACs targeting mutant EGFR PMID 32883633
Ac
A novel cell
Undecyl β
LRRK2
普鲁司特(Standard)
Eriodictyol 7
2
PHI
Pyrazolopyrimidines and pyrazolotriazines with potent activity against herpesviruses PMID 19700316
IL
Itgax Mouse Pre
Delta
The Emerging Role of the IL
3
5
Pyrrole[2,3
rel
Cancer preventive agents. Part 8 Chemopreventive effects of stevioside and related compounds PMID 19131254
AGEN
UCPH 102
20 4 Lyso PI
Phytogrowth
Discovery and Characterization of the First Nonpeptide Antagonists for the Relaxin
4
First
Synthesis, structure
GABA regulates the proliferation and apoptosis of head and neck squamous cell carcinoma cells by promoting the expression of CCND2 and BCL2L1 PMID 37866807
Isofezolac 50270
Prkca Rat Pre
building blocks
Calcium phosphate (GMP Like) (Secondary calcium (GMP Like))
胃膜素
4
memory
N
Lmna Rat Pre
碱性磷酸酶，胎盘（ALPP）基因
1
chronic rheumatoid arthritis
(E)
Discovery of RRx
ATP1B1 抗体 (YA2084)（ATP1B1 Antibody (YA2084)）
Cyclo(Tyr
4
CRAC intermediate2
Bradykinin acetate 6846
1
hiPSC
Ms
H
残杀威
Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors PMID 28792760
制菌磺
1
1
Synthesis and Antiviral Evaluation of Carbocyclic Nucleoside Analogs of Nucleoside Reverse Transcriptase Translocation Inhibitor MK
Kuwanon E (桑皮酮 E)
Antioxidant and antitumor activity of trolox, trolox succinate, and α
KRAS G12D ligand
皮质甾醇
Prexasertib (LY2606368)
西伯利亚远志呫吨酮A
Pcna
Auranofin 34031
Ms
NFh
IL
PDE
异丁司特(Standard)
BAY 73
B7
Mequindox (Standard)
Kainic acid, AMPA, and dihydrokainic acid effect on uptake and efflux of D
安曲南(Standard)
Etifoxine (Standard) (HOE 36
DSB
Inidascamine (RL
5
Apomorphine hydrochloride
DL
Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal
ZLC491
PCPr hydrochloride
FGF
Synthesis and biological evaluation of novel thienopyrimidine derivatives as diacylglycerol acyltransferase 1 (DGAT
Antiangiogenic agent 6
Design, synthesis, biological evaluation and docking studies of novel 2
Bcr
Dichlorobis(benzonitrile)palladium(II)
Prostaglandin D 3
D
红杉碱 A
CoREST/LSD1 degrader
Reverse two
STAT3 degrader
Evernic Acid A Low
partial
黄连素硫酸盐
13,14
WIN 62,577
Glipizide (Standard) (CP 28720 (Standard)，格列吡嗪(Standard))
Suzetrigine phenol
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