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Tributyrin
Design, synthesis, and in vitro antiproliferative activity of novel Dasatinib derivatives PMID 22217877
Indoxacarb effects on non
Tebotelimab
(E/Z)
Stearyldiethanolamine
EBOV抑制剂、基因
C6 NBD Galactosylceramide
特应性皮炎 (Atopic Dermatitis)
Cathelicidin
II 型糖尿病 (Type 2 Diabetes)
Hif1a Mouse Pre
Pgp
MIJ 821
EGFR
NKK105
MMs 02943764
Arc regulates brain damage and neuroinflammation via Sirt1 signaling following subarachnoid hemorrhage PMID 37820952
腺病毒类感染 (Adenovirus Infection)
肺腺癌 (Lung Adenocarcinoma)
α
Extractants
Collagen Type II (undenatured) (II型胶原蛋白 (非变性))
Estrone
An antagonistic role of clock genes and lima1 in kidney regeneration PMID 39789202
Kobusine derivative
iPLA2β regulates the dual effects of arachidonic acid in thyroid cancer PMID 39290130
5
t
t
哮喘 (Asthma)
Triad3A displays a critical role in suppression of cerebral ischemic/reperfusion (I/R) injury by regulating necroptosis PMID 32460187
OSU
IRF5
松香
Effect of TAT
Ginsenoside Rb1 41753
Glycyl
In vitro assessment of ferroptosis of cells exposed to cigarette smoke aerosol using a self
Desmethylrizatriptan
Eutopic macrophages facilitate endometriosis progression via ferroptosis
MYCN mediates TFRC
Animal
PBMCs
Tolbutamide
coral snake venom
盐酸地尔硫卓
Tumor
KP 1339
17α
Zap70 Rat Pre
MCE
UIC1005
Hesperidin Is a Promising Nutraceutical Compound in Counteracting the Progression of NAFLD In Vitro PMID 40649760
SCH 527123
Caryomitosis
METTL3
deoxy
Erianin induces GSDMD
3
Elevated levels of intracellular RNA lariats suppress the antiviral response PMID 39677789
S
Inhibition of SGK1 confers vulnerability to redox dysregulation in cervical cancer PMID 31136958
Sanggenon D 81422
Heparin
Cyantraniliprole (Standard) (HGW
4
AMBRA1 promotes dsRNA
花萼海绵体诱癌素A
Rimantadine hydrochloride 1501
PLA2G7 蛋白, Mouse (HEK293, His, Myc)
Myosin modulator Aficamten inhibits force in cardiac muscle by altering myosin's biochemical activity without changing thick filament structure PMID 40463178
过敏性鼻炎 (Allergic Rhinitis)
美罗培南
AP
bladder cancer
1
Targeting PAR2 Overcomes Gefitinib Resistance in Non
androgen
FKBP12 Ligand
Methuosis Inducer SGI
CCL4 蛋白, Human (His)
MDH2 regulates the sensitivity of clear cell renal cell carcinoma to ferroptosis through its interaction with FSP1 PMID 39138167
R5 peptide
Curzerene Induces Apoptosis in Colorectal Cancer Cells Through Inhibition of MEK/ERK Signaling Pathway PMID 40053192
MK 0366
Discovery of 2
AG6033 329706
Ginsenoside RK1 Promotes Hepatic Stellate Cell Glycolysis
Amlodipine aspartate (Standard)
9
Desalkylgidazepam (Bromonordiazepam)
Ryanodine
X
SUC2 蛋白, Saccharomyces cerevisiae (P.pastoris, His)
Methylhydroquinone (Standard)
AZD8154
Solenopsis invicta
FGFR2
5
Ethyl 4
Top Publications Citing MCE Products
DJ
Eupalinolide A induces autophagy via the ROS/ERK signaling pathway in hepatocellular carcinoma cells in vitro and in vivo PMID 36111510
MST4 kinase regulates immune thrombocytopenia by phosphorylating STAT1
Metallothioneins protect against isoconazole nitrate
缺血再灌注损伤 (Ischemia
Glia maturation factor
Indoxyl sulfate exacerbates alveolar bone loss in chronic kidney disease through ferroptosis PMID 38934473
Serine Biosynthesis Pathway Supports MYC
Sciadopitysin
Drug Metabolite
Yunnan baiyao exerts anti
VS 6063
Afoxolaner 1093861
Telaglenastat
Sulfo
激素受体阳性乳腺癌 (Luminal Breast Cancer)
Glycine Receptor (GlyR)
PFK
LMI
BKI
Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L
The role of B
Atrial Natriuretic Peptide
Nano
Nortriptyline (Standard)
Bombesin receptor
Proteasome inhibition induces apoptosis through simultaneous inactivation of MCL
Morusin induces paraptosis
Antennapedia Peptide TFA (Penetratin peptide TFA)
HPK1
LDN
PI3K mediates tumor necrosis factor induced
Tetrahexyldecyl Ascorbate
Calreticulin
Phospho
Dexpramipexole dihydrochloride (Standard) ((R)
5
Glucose Deprivation
AIM2
Hepatocyte necroptosis is associated with liver damage in dairy cows with ketosis PMID 40513868
Caspase
Calycosin Inhibit PANoptosis and Alleviate Brain Damage A Bioinformatics and Experimental Verification Approach PMID 40156525
KLX ameliorates liver cancer progression by mediating ZBP1 transcription and ubiquitination and increasing ZBP1
幽门螺杆菌感染 (Helicobacter Pylori Infection)
SHH 蛋白, Mouse
SNS‑032 combined with decitabine induces caspase‑3/gasdermin E‑dependent pyroptosis in breast cancer cells PMID 40070781
Famotidine (GMP) (MK
Melatonin protects against particulate matter
Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair PMID 39500322
Cancer cell
An investigation of reconstituted terlipressin infusion stability for use in hepatorenal syndrome PMID 33273555
The involvement of the Stat1/Nrf2 pathway in exacerbating Crizotinib
Zinc oxide nanoparticles disrupt the mammary epithelial barrier via Z
H
Mitochondrial Dysfunction by FADDosome Promotes Gastric Mucosal Injury in Portal Hypertensive Gastropathy PMID 38725851
Emerin 抗体 (YA6564)(Emerin Antibody (YA6564))
Evaluating the cytotoxicity mechanism of the cell
4
Ultrapotent chemogenetics for research and potential clinical applications PMID 30872534
Isoliquiritigenin induces HMOX1 and GPX4
mmu
Hydroxychloroquine Potentiates Apoptosis Induced by PPAR α Antagonist in 786
(S)
PGAM5 Regulates DRP1
Cerebrocrast (IOS
L48H37 343307
PT
Phosphoinositide specific phospholipase Cγ1 inhibition
ZM484
TRADD Mediates RIPK1
Deferoxamine Ameliorates Compressed Spinal Cord Injury by Promoting Neovascularization in Rats PMID 32383023
High
TRP
Ganciclovir mono
NR3C3
Enpp3 Rat Pre
PP
SAR
Somatic gene delivery faithfully recapitulates a molecular spectrum of high
c(phg
阿尔茨海默病 (Alzheimer's Disease)
Nelonicline (ABT
1
Macrophage ferroptosis promotes MMP2/9 overexpression induced by hemin in hemorrhagic plaque PMID 37696298
PPARs
Shikonin induces mitochondria
L
GM
BXPC
Magnolol targets CCND1 to suppress the proliferation of cholangiocarcinoma cells by inhibiting the Akt and STAT3 pathways PMID 41161542
Cy5
glucosamine
Isocarboxazid (异卡波肼)
Norethindrone
N
L
HQ
ICI 192605
Liquiritigenin, an Active Ingredient of Liquorice, Alleviates Acute Kidney Injury by VKORC1
Dabigatran etexilate
Growth inhibition activity of thioacetal artemisinin derivatives against human umbilical vein endothelial cells PMID 14552753
7
Famotidine
Sedaxane
In
Relative activity of some inhibitors of mono
Isocarboxazid (Standard) (异卡波肼 (Standard))
Glycerol
BRK/PTK6
RKO cells
Watermelon ketone (Standard) (7
JNJ61186372
Kuwanol A
帕金森病 (Parkinson's Disease)
Glycerol
Exposome
Matairesinol 580
A high
Pcsk9
Jasminin
LY 301875
lack of parathyroid hormone
Chromobox protein homolog 7 (CBX7) deficiency inhibits osteoblast ferroptosis by activating the Nrf2 function in type 2 diabetic osteoporosis PMID 40998236
Chaotropic agent
Ethylenediaminetetraacetic acid trisodium salt (Standard) (依地酸三钠盐 (Standard))
Ellagic acid mediated pyroptosis in hepatocellular carcinoma via the ESR1/G6PD pathway PMID 40680865
FMAU
Top Publications Citing MCE Products
转移性乳腺癌 (Metastatic Breast Cancer)
FTY720 induces neutrophil extracellular traps via a NADPH oxidase
HDAC6 promotes cell proliferation and confers resistance to temozolomide in glioblastoma PMID 27267806
Anti
Famotidine
Inhibition of ferroptosis protects intrahepatic bile duct cells against ischemia
Oxidative stress
HPV16
Isoprenaline
IFNG
Lactate
Identifying Potent Compounds Using Pairwise Consensus Methods PMID 40366258
Cell
5,6
Molecular hybridization
Butein
肺大细胞癌 (Large Cell Lung Carcinoma)
TRAM39
Hyperphosphorylation of EGFR/ERK signaling facilitates long
Phospho
MCE
Construction of pH
(Rac)
Roles of gut microbiome
Copper sulfate pentahydrate, for cell culture, 98%
Amlodipine maleate (Standard)
Peceleganan (PL
TRAM39
FMAU
Amlodipine maleate (Standard)
Budesonide
Glycerol
S516
(Rac)
IFN
Isoprenaline
Copper sulfate pentahydrate, for cell culture, 98%
Butein
稻提取物 (Oryza sativa Linn.)
Budesonide
Ubiquitin
S516
Andrographolide sensitizes human renal carcinoma cells to TRAIL‑induced apoptosis through upregulation of death receptor 4 PMID 33000263
TRKA
Crucial Roles of the RIP Homotypic Interaction Motifs of RIPK3 in RIPK1
Detailed functional characterization of four nanobodies as positive allosteric modulators of the human calcium
Glycerol
N
Gut stem cell necroptosis by genome instability triggers bowel inflammation PMID 32296174
Jasmoside
TRKA
Andrographolide Enhances TRAIL
Glycyrrhizic acid ameliorates LPS
Role of heparan sulfate in the Zika virus entry, replication, and cell death PMID 30684694
6
BNP 32
A Novel Naphthyridine Derivative, 3u, Induces Necroptosis at Low Concentrations and Apoptosis at High Concentrations in Human Melanoma A375 Cells PMID 30274263
BNP 32
6
RH12
Rgs2 Rat Pre
TRADD mediates the tumor necrosis factor
FGL2 蛋白, Mouse (HEK293, His
cell growth
Ecological toxicity reduction of dinotefuran to honeybee New perspective from an enantiomeric level PMID 31200156
cell growth
LCKLSL 533902
三阴性乳腺癌 (Triple
Propargyl
Ficolin 3 promotes ferroptosis in HCC by downregulating IR/SREBP axis
Inhibitory effects of lodoxamide on eosinophil activation PMID 9652307
HucMSC
NCGC00138783 TFA
Noncanonical feedback loop between RIP3
Tiliroside induces ferroptosis and suppresses tumor growth by synergistically targeting AKR1B1 and modulating iron metabolism in ovarian cancer cells PMID 40187595
CAL 101
METTL1
Imexon (BM 06002,亚美克松)
The RIP3 activator C8 regulates the autophagy flux mediated by p62 and promotes the immunogenic form of cell death in human gastric cancer cells PMID 39520785
Salmonella pSLT
CAMK2/CaMKII activates MLKL in short
GSK
Spatiotemporally Engineered Protein Delivery via Integrated Covalent Coupling and Pathological Triggers for Precision Microenvironment Reprogramming in Tissue Injury Repair PMID 40981608
Amlodipine benzenesulfonate (Standard)
LY3009120 1454682
Toosendanin
adjuvant reagent
DHA attenuates Aβ
R50547
肥胖症 (Obesity)
CDKs
Coupling Between Interleukin
Pevonedistat 905579
CA IX/GPX4
Tetramethylammonium silicate solution
Lycopene inhibits zearalenone
CXC chemokine receptors
Dextran
鸟苷 (Guanosine)
(R)
BAF170 抗体 (YA6479)(BAF170 Antibody (YA6479))
高血压 (Hypertension)
Methylhydroquinone 95
Remimazolam impurity 4 (Standard)
tocolytic agent
CB1/2
trans
Methyl dihydrojasmonate (Standard) (二氢茉莉酮酸甲酯 (Standard))
Anti
CCT2 蛋白, Human (His
2
Chloridazon
CP 945598
TG6
Sodium phosphate monobasic, for cell culture
4
小细胞肺癌 (Small Cell Lung Cancer)
肺鳞状细胞癌 (Lung Squamous Cell Carcinoma)
allergic
pfi
Glycerol
(2R)
Bromopride hydrochloride
Nocistatin(human) TFA
Tubulin inhibitor 8
Novel pharmacological activity of loperamide and CP
MAO
EGF promotes PKM2 O
OATD02
Receptor
RIPK
RIP kinase
Indoleamine 2,3
GSK3326595 is a promising drug to prevent SARS
Anthocyanins Prevent Mastitis Exacerbation by Inhibiting PANoptosis Activation PMID 40552401
Photoactive metal
MLKL triggers NLRP3 activation in sodium arsenite
Tat
Faecalibacterium prausnitzii
Teludipine
MCE
Glycidol induces necroptosis and inflammation through autophagy
Single
Inhibition of RIP1
RIP3 knockdown inhibits necroptosis of human intestinal epithelial cells via TLR4/MyD88/NF
D
AT
A Novel Identified Circular RNA, mmu_mmu_circRNA_0000309, Involves in Germacrone
NMUR1拮抗剂、基因
Emodin induced necroptosis in the glioma cell line U251 via the TNF
Metipranolol 22664
Osthole induces necroptosis via ROS overproduction in glioma cells PMID 33350608
Cysteine Deprivation Targets Ovarian Clear Cell Carcinoma Via Oxidative Stress and Iron
Elobixibat
renal allograft
Free heme induces neuroinflammation and cognitive impairment by microglial activation via the TLR4/MyD88/NF
A phenazine analogue of actinomycin D PMID 573799
Activation of mGlu2/3 receptors in the striatum alleviates L
AD model
Tsugalactone (铁杉内酯)
(8Z,11Z,14Z,17Z)
Pseudopelletierine
非酒精性脂肪性肝炎 (Nonalcoholic Steatohepatitis)
Endoplasmic reticulum stress
cis
Heme Oxygenase
Heme Oxygenase (HO)
α
MCE
The inhibitory potency and selectivity of arginine substrate site nitric
Azedarachol
Smad2
Exosomal miRNA
Non
115D8
Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer PMID 34221865
Evaluation of the Liver Toxicity of Pterocephalus hookeri Extract via Triggering Necrosis PMID 30832306
PFM
7 I, a structurally modified sinomenine, exerts dual anti
PLD
4
Cell death induced by nicotine in human neuroblastoma SH
卢立康唑
Mycobacterium tuberculosis suppresses host DNA repair to boost its intracellular survival PMID 37848028
Resveratrol analog1
UBE2T
Inhibition of immune checkpoints PD
SP
Corosolic acid inhibits EMT in lung cancer cells by promoting YAP
Optimization of 8
eNOS pT495 decoy peptide
Pyridinoline
SBI
Nuclear factor
Nuclear factor
NF
AEEA
fragmented
GSK1820795A 2650253
Sciadopitysin 521
Cationic biaryl 1,2,3
Fmoc
Sphinganine (d18 0)
Benzyltriethylammonium chloride 56
苯溴马龙
Nitric oxide synthases
Fmoc
NG 95
3
Keap1
ZLC491 3053716
Pyridoxal 66
c
Phase Ia Study of Anti
Application of Bone Marrow Mesenchymal Stem Cells Effectively Eliminates Endotoxemia to Protect Rat from Acute Liver Failure Induced by Thioacetamide PMID 35122584
GSK 2315698
Interleukin Related
1
Acacetin
Heptadecanoic acid 506
AM 404
GM
4
PTP1B promotes the malignancy of ovarian cancer cells in a JNK
METAP1D/Methionine aminopeptidase 1D 蛋白, Human (His)
VEGF
MCE
F16 36098
全球办事处
SMD
DSPE
骨髓细胞瘤癌基因(Myc)基因
Carbohydrate
BI
TA
H
CDK8
Imipramine
Comparison of the induction of hepatic peroxisome proliferation by the herbicide oxadiazon in vivo in rats, mice, and dogs and in vitro in rat and human hepatocytes PMID 8917673
G
macrophage immune checkpoint
Effect of quercetin 7
Design and synthesis of novel pyrimidine derivatives as potent antitubercular agents PMID 30508666
(Rac)
Glycine Receptor (GlyR)拮抗剂、基因
Diabetes model
FGIN 1
U87
O
Tumor protein D52 (isoform 3) induces NF
Quizalofop
Fmoc
NR
PLLA1000
Dioctyl phthalate
AlgMA (MW 300000)
Pepinh
Macrolide抑制剂、基因
1,2
Lentinellic acid
8
AR
2
Vitamin D Receptor/VDR 蛋白, Mouse (sf9, His)
PROTAC CDK4/6/9 degrader 1
Regenerating Chemotherapeutics through Copper
Tetraethylammonium tetrafluoroborate 429
MCE
PKB
MCE
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