最近收录_第573页_生物活性分子
生物活性分子最近更新
角蛋白 24（KRT24）基因
An Immunomodulating Regenerating Hydrogel That Rescues the Oxidative Microenvironment and Reverses Cell Senescence for Osteoporotic Bone Defects PMID 40754989
细胞色素 c 氧化酶铜伴侣 COX17（COX17）基因
二酰甘油激酶 zeta（DGKZ）基因
转化生长因子β受体 1（TGFBR1）基因
renal cell carcinoma
驱动蛋白家族成员 23（KIF23）基因
带电多泡体蛋白 2A（CHMP2A）基因
Brazilin (巴西苏木素)
Batatasin I (山药素I)
Amobam 3566
TGF
PHD 指蛋白 21A（PHF21A）基因
DR1 相关蛋白 1（DRAP1）基因
含三方基序 32（TRIM32）基因
SB251023 208842
bladder
PI3Kα
SALL4/ABCB6 Axis Suppresses Ferroptosis in Colon Cancer by Mediating Mitophagy PMID 40052371
SB
Phenotypic heterogeneity and plasticity in colorectal cancer metastasis PMID 40393458
Disrupting Complement
ionophore
过渡蛋白 1（TNP1）基因
TRIM34
hematologic
MCE
PF
核孔蛋白 93（NUP93）基因
NRG1
115950
NF2 Human Pre
RAS 相关 2（RRAS2）基因
PLEKHG4
网格蛋白重链（CLTC）基因
钙蛋白酶小亚基 2（CAPNS2）基因
Inhibition of γδ T Cells Alleviates Blood
Nicotinamide riboside activates SIRT3 to prevent paclitaxel
CXCL9(74
Boc
Targeting Dio3 to enhance mitophagy and ameliorate skeletal muscle wasting in sepsis PMID 40628122
含 BEN 域 5（BEND5）基因
Cideb Mouse Pre
跨膜蛋白 258（TMEM258）基因
PC9/gef
131616
RTN4 Human Pre
MCE
MCE
ME
含膜相关鸟苷酸激酶，WW 和 PDZ 结构域 1（MAGI1）基因
D
Germline variant GFI1
Tin(II) oxalate 814
Buddlejasaponin IV
OB
凝血因子 VII（F7）基因
CCR4
ADP 核糖基化因子 6（ARF6）基因
1
Anti
DB02307 101222
TNF 受体相关因子 6（TRAF6）基因
蛋白磷酸酶 2 催化亚基 β（PPP2CB）基因
MCE
ERBB2, 1 换能器（TOB1）基因
含 RALBP1 关联的 Eps 域 2（REPS2）基因
Dabigatran impurity 14 hydrochloride 1422435
RALY RNA 结合蛋白样（RALYL）基因
液泡蛋白分选 4 同系物 A（VPS4A）基因
动力蛋白轴丝轻链 4（DNAL4）基因
Nf2 Mouse Pre
1
self
含 SH3 结构域的无名指 2（SH3RF2）基因
CX4338
输出 1（XPO1）基因
N
核糖体蛋白 S25（RPS25）基因
RAB3A 相互作用蛋白 1（RAB3IL1）基因
MCE
氯离子通道附件 2（CLCA2）基因
X
含钾通道四聚结构域 9（KCTD9）基因
GPAT3 is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma PMID 38948063
PACAP (6
高度分化的同源框（HDX）基因
F
N3
ATPase H+ 转运 V0 亚基 a1（ATP6V0A1）基因
Sp1 转录因子（SP1）基因
Bend5 Mouse Pre
ELL 相关因素 1（EAF1）基因
BCX 1470
CYTH3 Human Pre
MCE
m
katanin 调节亚基 B1（KATNB1）基因
ERB 041
Ginsenoside (20)S
FGFR3 K650M Recombinant Human Active Protein Kinase
MCE
MCE
Sotalol hydrochloride (MJ 1999，盐酸索他洛尔)
MCE
MCE
Self
Desmethyl lacosamide
FLT3/HDAC
Tubulin/HDAC
MCE
MCE
MCE
Melinamide 14417
CB1 inverse agonist 2
CISD1 Human Pre
SULT1A3 蛋白, Human (N
AQP9 Human Pre
Clu
癌蛋白诱导转录物 3（OIT3）基因
晚期内体/溶酶体衔接子、MAPK 和 MTOR 激活因子 4（LAMTOR4）基因
Cedarwood terpenes 68608
Cinoctramide 28598
Col1a1
(R)
MCE
DAB2 Human Pre
LM
VT
(R)
DEAH 盒解旋酶 38（DHX38）基因
丝氨酸羟甲基转移酶 2（SHMT2）基因
MCE
Hexadecylpyridinium bromide 140
PCID2 Human Pre
1,4
CEF7, Influenza Virus NP (380
Thiazesim hydrochloride 3122
跨膜蛋白 95（TMEM95）基因
hCAI/II
核糖体蛋白 S6 激酶 A6（RPS6KA6）基因
Aldehyde Dehydrogenase (ALDH)
84330
含锌指和 BTB 结构域 7A（ZBTB7A）基因
Fhl5 Mouse Pre
Cyclohexanecarboxylic acid
PRMT1 抗体 (YA686)（PRMT1 Antibody (YA686)）
4
MCE
AQP5 Human Pre
Aqp9 Mouse Pre
DAB2IP Human Pre
MCE
端粒重复结合因子 2（TERF2）基因
21
1102
1
Propane sultone 1120
异质核核糖核蛋白 C 样 1（HNRNPCL1）基因
适配器相关蛋白复合物 2 亚基 mu 1（AP2M1）基因
1
147525
CD68 分子（CD68）基因
ST8 α
REST 核心阻遏物 3（RCOR3）基因
Dab2 Rat Pre
3
3,4,5
CB
DZIP3 Human Pre
MAPK1/ERK2 蛋白, Human (sf9, His)
1
ADAM 金属肽酶结构域 22（ADAM22）基因
3,5
Protein kinase inhibitor 13
Hexadecanedioic acid 505
HbpA from Glaesserella parasuis induces an inflammatory response in 3D4/21 cells by activating the MAPK and NF
OV329
Forsythoside A mitigates osteoarthritis and inhibits chondrocyte senescence by promoting mitophagy and suppressing NLRP3 inflammasome via the Nrf2 pathway PMID 39383631
Maltodextrin, dextrose equivalent 16.5
H
DO264
CD117/c
Kaempferol inhibits atherosclerotic plaque development via dual
BLOC1S5
3H
TNK1 is a ubiquitin
CAPNS2 Human Pre
CAPS 1135
TREK inhibitor3
Elevated CD40 ligand silences α interferon production in an HIV
RAB25 Human Pre
PPM1B Human Pre
Glimepiride overcomes acquired resistance to EGFR TKIs in lung cancer via the AMPK/ERK/MMP7 signaling pathway PMID 40659128
MCE
Jinlida granules alleviate podocyte apoptosis and mitochondrial dysfunction via the AMPK/PGC‑1α pathway in diabetic nephropathy PMID 39670303
Thromboxane A2 receptors in prostate carcinoma expression and its role in regulating cell motility via small GTPase Rho PMID 18172303
SHP504
Exploring the therapeutic potential of HAPC in COVID
tendency
RNF180 suppressed aggressiveness by degrading NOTCH1, TRIM24 and FOXC1, and chemoresistance by degrading ACC1 and ACLY in colorectal cancer PMID 40915184
The CXCL8/MAPK/hnRNP
A CD4+ T lymphocyte
The adaptor protein AP
YT117R
Peptide inhibition of myointimal proliferation by angiopeptin, a somatostatin analogue PMID 1673136
Rice extracellular vesicles send defense proteins into fungus Rhizoctonia solani to reduce disease PMID 39755117
Glycolysis inhibition induces anti
Synthesis and anti
GIP, rat TFA
Pyroptotic
Quercetin Protects against Silicon dioxide Particles
SULT1A3 蛋白, Human (His, solution)
S
微管蛋白α4a（TUBA4A）基因
MCE
Radiation Induces Pericyte
Metformin sensitizes triple
Sex hormone receptors, calcium
83900
Kuntai Capsules Improve Premature Ovarian Failure by Regulating AMPK
The Triple Combination of Recombinant Methioninase, Rapamycin, and Chloroquine Synergistically Eradicates HCT116 Colon Cancer Cells PMID 40578963
Transglutaminase 2 promotes breast cancer cell autophagy by targeting p53/ mTOR axis PMID 40216264
Differential impacts of ribosomal protein haploinsufficiency on mitochondrial function PMID 39786340
PDP
Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization PMID 40472086
N
4
Quinacrine induces autophagy via the Dlg5/AKT pathway to inhibit osteosarcoma cell proliferation and suppresses migration and invasion through the Dlg5/Girdin pathway PMID 40541124
生长停滞特异性 8（GAS8）基因
81629
lymphocytes
Rbms3 Mouse Pre
转录激活抑制因子家族成员 2（TASOR2）基因
leukaemia
MCE
含 BAR/IMD 结构域的衔接蛋白 2（BAIAP2）基因
肌钙蛋白 I2，快速骨骼型（TNNI2）基因
亚当斯样 5（ADAMTSL5）基因
磷脂酶 C β 1（PLCB1）基因
保护端粒 1（POT1）基因
清道夫受体 F 类成员 1（SCARF1）基因
Benzoctamine (Ba
3
GSPT2 degrader
含三方基序 46（TRIM46）基因
NXN
Biotinylated isoxazole
113829
CDK1
Animal
Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer PMID 38262412
Targeting mesenchymal monocyte
Bhimanone
Macrophage autophagy deficiency
D
HO
MCE
蛋白磷酸酶 2 调节亚基 B''beta（PPP2R3B）基因
Poloppin
CDK9
Hyperglycemia
81851
Ppm1b Rat Pre
JBPOS
Lathyrol 34420
ATL 1102 sodium (ISIS
嘌呤能受体 P2X 7（P2RX7）基因
pan
溶质载体家族 30 成员 8（SLC30A8）基因
Composite hydrogel
MCE
smoke
MA 0211
Carisbamate (RWJ
Anhydro abiraterone 154229
MCE
hepatic fat accumulation
TP
headaches
Quinamine 464
deacetylase
Biotin
mTORC1
Ksr1 Rat Pre
immunosuppressant
nuclear
YT 146
2576
蛋白酶体 26S 亚基泛素受体，非 ATPase 2（PSMD2）基因
CCR4
PARL
MCE
MCE
2’
2
Capn2 Mouse Pre
E2F 转录因子 1（E2F1）基因
鸟氨酸脱羧酶抗酶 3（OAZ3）基因
含锌指和 BTB 域 12（ZBTB12）基因
AMS
Neuroprotective agent 10
Ppp1r12a
调节因子 X6（RFX6）基因
核受体共激活因子 6（NCOA6）基因
MCE
Lck 交互跨膜适配器 1（LIME1）基因
MCE
SRX3177 2241237
Ptpn11 Rat Pre
RAD50 交互器 1（RINT1）基因
MYC 结合蛋白 2（MYCBP2）基因
组蛋白脱乙酰酶 7（HDAC7）基因
220929
NAD (P) HX 脱水酶（NAXD）基因
Tank
AG
Dihydroorotate Dehydrogenase
Elizabethin 78361
DHODH
SEW2871 (Standard)
MCE
缝隙连接蛋白β6（GJB6）基因
CDC25
MCE
JPS035
H
N3
pH
MCE
MC2625
MCE
MCE
MCE
HM12
Tripelargonin 126
MCE
MCE
N
Nanocage encapsulation improves antiepileptic efficiency of phenytoin PMID 32087458
ADAP1 Human Pre
MCE
ZYG11B potentiates the antiviral innate immune response by enhancing cGAS
TGF
含无菌 alpha 基序结构域 4B（SAMD4B）基因
Bone marrow microenvironment drives AML cell OXPHOS addiction and AMPK inhibition to resist chemotherapy PMID 34927743
Low
Neocopiamycin B 113189
HMGB1 Promotes the Release of Sonic Hedgehog From Astrocytes PMID 33868221
RANK promotes colorectal cancer migration and invasion by activating the Ca2+
Pseudoaspidin 478
Caricotamide (EP
Metformin enhances epithelial cell growth inhibition via the protein kinase
MPPG 169209
HDAC2
Spatiotemporally selective astrocytic ATP dynamics encode injury information sensed by microglia following brain injury in mice PMID 38862791
含卷曲螺旋结构域 102B（CCDC102B）基因
MCE
ULK1
TSC 复杂亚基 2（TSC2）基因
memory
Cl− Channels
OV329 hydrochloride
Carbonic anhydrase inhibitor 31
共济失调素 10（ATXN10）基因
DNA 交联修复 1B（DCLRE1B）基因
核受体相互作用蛋白 2（NRIP2）基因
84616
MCE
Valrocemide (TV1901，丙戊塞胺)
ETS1/EWSR2 蛋白, Human (His)
PF
PCK1 regulates neuroendocrine differentiation in a positive feedback loop of LIF/ZBTB46 signalling in castration
PTPN11 Human Pre
RWJ
NUP37
HPO
MCE
Genotoxic stress
Animal
W
Piroctone olamine (Standard) (Piroctone ethanolamine (Standard)，吡罗克酮乙醇胺盐 (Standard))
ALK5
DET1 和 DDB1 关联 1（DDA1）基因
Antiviral agent 24 23661
Phospho
PD
Cisd1 Rat Pre
Aqp9 Rat Pre
MCE
Pharmacokinetics and relative bioavailability of heptabarbital and heptabarbital sodium after oral administration to man PMID 9299
MCE
Fluopicolide 239110
159119
ZBTB42
Protein disulfide isomerase 37318
Ppm1b Mouse Pre
MCE
ACHE
MCE
152815
Aloracetam
Cd3e
NME/NM23 核苷二磷酸激酶 4（NME4）基因
BRISC 和 BRCA1 复合成员 2（BABAM2）基因
FCGR2A Human Pre
MCE
含菱形域 1（RHBDD1）基因
CDK7
POM121 跨膜核孔蛋白（POM121）基因
细胞膜穴样内陷相关蛋白 3（CAVIN3）基因
超极化激活环核苷酸门控钾通道 4（HCN4）基因
VSMC
The immunomodulatory effect of Poria cocos polysaccharides is mediated by the Ca2+/PKC/p38/NF
SB 239063
ARHB
Carisbamate
reductase
Snail/HDAC
DNA Base Pairing
Ndufa5
E2f1 Mouse Pre
牙源性，成釉细胞相关（ODAM）基因
含锌指 CCHC 型 14（ZCCHC14）基因
SEH1 样核孔蛋白（SEH1L）基因
TIA1 细胞毒性颗粒相关 RNA 结合蛋白样 1（TIAL1）基因
Plcb1 Mouse Pre
11
排序 nexin 3（SNX3）基因
中心体蛋白 19（CEP19）基因
N
OMDM
Stk3 Rat Pre
MCE
DMT
ADRB2 抗体（ADRB2 Antibody）
Dab2 Mouse Pre
L 152804 6508
Fequesetide
MCE
ATP 合成酶线粒体 F1 复合装配因子 1（ATPAF1）基因
STK3 Human Pre
氨甲酰磷酸合成酶 2、天冬氨酸转氨甲酰酶和二氢乳清酶（CAD）基因
端锚聚合酶 2（TNKS2）基因
Animal
c
磷脂酰肌醇 3
XIAP 相关因子 1（XAF1）基因
Columbianadin ameliorates rheumatoid arthritis by attenuating synoviocyte hyperplasia through targeted vimentin to inhibit the VAV2/Rac
CIDEB Human Pre
LU 2443
Rae1
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis PMID 34847376
PSB
MCE
MCE
跨膜蛋白 9（TMEM9）基因
(S)
Comparative pharmacokinetic analysis of latamoxef and CPW 86
HSPA6 Human Pre
2
RF03176
MCE
BG47
Downregulation of TrkB Expression and Signaling by Valproic Acid and Other Histone Deacetylase Inhibitors PMID 31308194
lin
外泌体组分 3（EXOSC3）基因
MCE
Early Mechanisms of Chemoresistance in Retinoblastoma PMID 36230889
A cholecystokinin agonist/antagonist according to dose and time of action effect on food intake PMID 2093151
A Novel Combination Approach Targeting an Enhanced Protein Synthesis Pathway in MYC
Docosyl docosanoate 17671
4
MCE
Ets1 Rat Pre
Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer PMID 39591412
11
MCE
(p
Antifungal agent 11
peptide segment
STK24 Human Pre
(
G2/M phase
pocket
Supervillin promotes epithelial
DPP8/9
NSC 104999
泛素结合酶 E2 J1（UBE2J1）基因
表皮生长因子受体通路底物 15 like 1（EPS15L1）基因
TAT (47
SLIT
BLM RecQ 样解旋酶（BLM）基因
核孔蛋白 85（NUP85）基因
染色体解旋酶 DNA 结合蛋白 3（CHD3）基因
血清/糖皮质激素调节激酶 1（SGK1）基因
440563
丝裂原活化蛋白激酶 11（MAPK11）基因
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