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生物活性分子最近更新
HAoSMCs
(3aR,9aR)
BAY 73
Antitumorigenic
Win 45164 83880
The correlation between cellular O
Recombinant Methioninase Lowers the Effective Dose of Regorafenib Against Colon
Tetradecyltrimethylammonium bromide 1119
Monoacylglycerol lipase inhibitor JJKK048 ameliorates ABCG2 transporter
Toluidine blue (ZnCl2) 6586
Triggering of Suicidal Erythrocyte Death by Regorafenib PMID 26765545
Ensemble
MCE
Smad6 Mouse Pre
凝血因子 II (凝血酶) 受体样 2（F2rl2）基因
MCE
N
zona
PSAP/Prosaposin 蛋白, Rat (HEK293, His)
Sodium
SGLT
PSAP Human Pre
Atp2b1 Rat Pre
Xanthine Oxidase
Pyruvate Kinase
Amylose 9005
Activation of AML1
Hydroxycarboxylic Acid Receptor (HCAR)
Parkinson
小核核糖核蛋白 D1 多肽（SNRPD1）基因
Mdn1 Rat Pre
Methoxatin disodium salt (Standard)
BTTES
2
bipolar disorder
CB65 913534
Angiotensin
DMTr
L
Petromurin C
K
Paeciloquinone A
Ptpn1
芳烃受体相互作用蛋白（AIP）基因
NUMB 样内吞衔接蛋白（NUMBL）基因
A
MCE
MI
Sulfanegen
成纤维细胞生长因子 2（FGF2）基因
FGR 原癌基因，Src 家族酪氨酸激酶（FGR）基因
DMTr
热休克蛋白家族 A (Hsp70) 成员 4（HSPA4）基因
丝裂原活化蛋白激酶激酶激酶 12（MAP3K12）基因
MCE
粘蛋白 1，细胞表面相关（MUC1）基因
核受体亚家族 3 C 组成员 1（NR3C1）基因
Chn1 Rat Pre
MCE
CRTAM/CD355 蛋白, Cynomolgus (HEK293, Fc)
(2R,4S)
Technical Support
UK
Technical Support
m
MCE
Technical Support
CHMP1B Human Pre
DMTr
Demethylvestitol 65332
Technical Support
MCE
Technical Support
PGE2
Technical Support
Boc
Technical Support
L
Organoid modeling identifies USP3
Technical Support
Endometrial stromal Menin supports endometrial receptivity by maintaining homeostasis of WNT signaling pathway through H3K4me3 during WOI PMID 40610728
Reverse abasic phosphoramidite
MCE
MCE
MCE
MCE
Technical Support
MCE
MCE
含核苷酸结合寡聚化结构域 1（Nod1）基因
含缬酪肽蛋白（Vcp）基因
1,2
pre
Methyl4,6
CHN1 蛋白, Human (sf9, His
Tirilazad 110101
MCE
Fgf18 Rat Pre
MCE
Serratiopeptidase (Brasan，沙雷菌蛋白酶)
CDK8
CDK7
ABI3BP Human Pre
MCE
Selective Covalent Targeting of Mutated EGFR(T790M) with Chlorofluoroacetamide
KRN951, a highly potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, has antitumor activities and affects functional vascular properties PMID 16982756
MHY1485 ameliorates UV
Phospho
Carbomer 676 (卡波姆676)
MCE
MCE
MCE
MCE
PARP1
N6
BAY 43
MCE
ABCB1 蛋白, Human (HEK293, Flag)
MCE
Aprt
1H
4,4'
Gas6
锌指 DHHC 型棕榈酰转移酶 3（ZDHHC3）基因
极光激酶 A（AURKA）基因
20
Calpain
Boc
MCE
Y
DMTr
DMTr
12
Olr1 Rat Pre
L
5,6,7,8
ZK
3
Boc
9
DMTr
MCE
MCE
NXT629
CDK6
MCE
2’
MCE
XO
XMD8
(±)11
Wee1
Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon PMID 17471315
5
Molecular insights into the α6β4 nicotinic acetylcholine receptor function and ligand recognition PMID 40175361
Transport and inhibition mechanisms of the human noradrenaline transporter PMID 39085602
4
Org 21465
MCE
Closed
MCE
Role of Mitochondrial Reactive Oxygen Species in Chemically
MCE
Dilaurylglycerosulfate sodium 99388
The IRF2/CENP
Ligand Phase Separation
MCE
DMTr
PARP1
含 KH RNA 结合域，信号转导相关 3（KHDRBS3）基因
MCE
Sp2 Transcription Factor Alleviates Chondrocyte Loss in Osteoarthritis by Repressing the DVL1
AAV
Identifying cross
An acidic residue within the OCT4 dimerization interface of SOX17 is necessary and sufficient to overcome its pluripotency
A direct interaction between the Chd1 CHCT domain and Rtf1 controls Chd1 distribution and nucleosome positioning on active genes PMID 39677735
Rapid conversion of porcine pluripotent stem cells into macrophages with chemically defined conditions PMID 38097188
BCL2 is a major regulator of haploidy maintenance in murine embryonic stem cells PMID 37144356
(S,S)
CHIR99021
Protocol for capturing trophectoderm stem cells reflecting the blastocyst stage PMID 36930647
P21
MCE
Spacer C12 phosphoramidite
MCE
MCE
MK2 promotes Tfcp2l1 degradation via β
MCE
MCE
H
Gadd45g initiates embryonic stem cell differentiation and inhibits breast cell carcinogenesis PMID 34601500
Velvet antler polypeptide
SHP2 promotes proliferation of breast cancer cells through regulating Cyclin D1 stability via the PI3K/AKT/GSK3β signaling pathway PMID 32944401
DMTr
AR ligand
阿拉丁 WD 重复核孔蛋白（AAAS）基因
FSCCL
MCE
The PPARs from orphan receptors to drug discovery PMID 10691680
肌球蛋白重链 7（MYH7）基因
Spacer phosphoramidite 9 (Spacer
DMTr
MCE
DMTr
MCE
MCE
Synthetic approaches for novel fused pyrimidine derivatives Design, structural characterization, antiviral, antitumor, and molecular docking evaluation PMID 39720060
Glucosyringic acid 33228
4
PKR Inhibitor, negative control
DHFR
vascular permeability
Naproxen glucuronide 41945
4
peripheral benzodiazepine receptor
Cernuine 6880
MCE
(Z)
D
RABGGTA Human Pre
3,4
MCE
HLA
MCE
苯丙氨酰
M2698 (Standard)
N,N,N
MCE
Tspan7
TAK1 抗体 (YA6190)（TAK1 Antibody (YA6190)）
TAK1 抗体 (YA663)（TAK1 Antibody (YA663)）
TAB1(N
Phospho
AMOZ
FGF18 Human Pre
精子发生和卵子发生特异性基本螺旋
MyoD 家族抑制因子（MDFI）基因
Systemic immune activity occurs during human immune system maturation PMID 41161316
Family with sequence similarity 114 member A1 orchestrates immune evasion in triple
Pathogen
Body
Glucose starvation mimetic aldometanib removes immune barriers permitting mice with hepatocellular carcinoma to live to normal ages PMID 41286115
MAPK
Inhibitors supercharge kinase turnover through native proteolytic circuits PMID 41299171
Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2 PMID 41308123
Pulsed electromagnetic fields inhibit atherosclerosis by regulating pyroptosis through membrane tension
MUCIN 1 confers inflammatory memory of tyrosine kinase inhibitor resistance in non
ExoSloNano multimodal nanogold labels for identification of macromolecules in live cells and cryo
Innate immune and metabolic signals induce mitochondria
Interaction between CDC6 and Tmod3 accelerates resistance to paclitaxel through focal adhesion assembly PMID 41339304
Bioprinting of live platelet
Food
Genetically engineered MSCs overexpressing hepatocyte growth factor for the treatment of human refractory wounds PMID 41381331
Hyaluronan regulates the assembly structure and biofunction of polycationic silk fibroin to boost microfracture PMID 41403565
Designed bone
MCE
MCE
One
DMTr
Delta
MCE
MCE
Psph Rat Pre
Pyridine
L
par
Vitamin C as an antioxidant evaluation of its role in disease prevention PMID 12569111
MCE
DMTr
Antibacterial agent 237
1
MYOG Human Pre
HDAC6
MCE
MCE
Terrein 582
Lys01
MCE
11(R)
Ggta1 Mouse Pre
N
MCE
MCE
AKOS B018304 6308
Apelin agonist 2
DMTr
MCE
MCE
MDN1 Human Pre
MCE
MCE
MCE
伪君子受体 1（HCRTR1）基因
Ethane
Deoxynojirimycin tetrabenzyl ether 69567
6
Fmoc
Dicloralurea 116
MCE
MCE
7
MCE
MCE
MCE
GNB1L Human Pre
dopamine
LRRK2
airway inflammation
cAMP 反应元件结合蛋白 1（CREB1）基因
NIK links inflammation to hepatic steatosis by suppressing PPARα in alcoholic liver disease PMID 32206109
Activation of the MEK1
ABI3 Human Pre
MCE
Advancing fatty liver research in dairy cows Development of a bovine liver organoid model PMID 40675485
MCE
Suberic acid 505
Modeling diabetic cardiomyopathy using human cardiac organoids Effects of high glucose and lipid conditions PMID 39984109
CGREF1 modulates osteosarcoma proliferation by regulating the cell cycle through the Wnt/β
Toll
MCE
Nerindocianine 748120
Heparin disaccharide IV
Characterisation of extraembryonic endoderm
MCE
Pristimerin suppresses colorectal cancer through inhibiting inflammatory responses and Wnt/β
MCE
Aryl hydrocarbon receptor mediates the cardiac developmental toxicity of EOM from PM2.5 in P19 embryonic carcinoma cells PMID 30384306
MCE
Crosstalk between AhR and wnt/β
MCE
Selective glycogen synthase kinase 3 inhibitors potentiate insulin activation of glucose transport and utilization in vitro and in vivo PMID 12606497
MERTK Human Pre
MCE
Myog Rat Pre
Tenellin 53823
SK
超氧化物歧化酶铜伴侣（CCS）基因
YM 53403 851331
MCE
MCE
Myogenin 抗体（Myogenin Antibody）
MCE
MCE
4
MCE
细胞色素 b5 还原酶 1（CYB5R1）基因
Methyl acetylacetate
MCE
N4
MCE
8
AdemA
hydroxycarboxylic acid receptor 1
glutamate
MCE
MCE
Braxlosiran
MK
Pep2m, myristoylated (Myr
Tris(2,4
Rhododendron collettianum Aitch. & Hemsl.提取物 (Rhododendron collettianum Aitch. & Hemsl.)
Chloroquine
MCE
MCE
SEM1 26S 蛋白酶体亚基（SEM1）基因
Trebenzomine 23915
Enhanced conversion of T cells into CAR T cells by modulation of the MAPK/ERK pathway PMID 39938523
Ala
Effects of BIM26226, a potent and specific bombesin receptor antagonist, on amylase release and binding of bombesin
Evidence that CA3 is Underling the Comorbidity Between Pain and Depression and the Co
Design, synthesis, and biological evaluation of piperazine derivatives as pan
S
DMTr
6
Fmoc
New glycosidases inhibitors, panosialins D and wD produced by Streptomyces sp. OH
Click chemistry, a powerful tool for pharmaceutical sciences PMID 18509602
RG6652
RGS14
NK
LB
AVI 4206
BMS
DC371739
Duvakitug 2750005
MCE
L
A1155905
MCE
DMTr
ZD
ZLY 28
Mesuol
DMTr
D
Pruvonertinib
RO
Cerebrocrast
Evonimine
2& 039;
Bromotetrandrine
甘油单酯脂肪酶（MGLL）基因
Tufm lactylation regulates neuronal apoptosis by modulating mitophagy in traumatic brain injury PMID 39496783
CaMKII and Kalirin, a Rac1
Pharmacophore Recombination Design, Synthesis, and Bioactivity of Ester
SLC
Benzo[b]fluoranthene
Licochalcone D inhibits osteoclast differentiation and postmenopausal osteoporosis by inactivating the NF
Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells PMID 22460505
H2S inhibits LiCl/pilocarpine
Role of Nox4 in High Calcium
Activation of TAS2R4 signaling attenuates podocyte injury induced by high glucose PMID 38942091
L
111In
3
Anticancer effect of SN
TREX1
L
BTX
DMTr
PARP/VEGFR3
Nrf2 activator
10
Py2T
Amcipatricin L
连环蛋白α1（CTNNA1）基因
(Rac)
Succinamic acid
DMTr
MCE
Lum Mouse Pre
MCE
MCE
5
SP
Modimelanotide (ABT
Bis
Desmethyl Naproxen
Neutrophil Extracellular Traps Induce Abdominal Aortic Aneurysm Formation by Promoting the Synthetic and Proinflammatory Smooth Muscle Cell Phenotype via Hippo
Targeting YES1 Disrupts Mitotic Fidelity and Potentiates the Response to Taxanes in Triple
A novel GLP
MCE
absorbable
Suberic acid
DMTr
MCE
6'
MCE
UNC5293
Substance P(1
Small
Targeting ALK2 An Open Science Approach to Developing Therapeutics for the Treatment of Diffuse Intrinsic Pontine Glioma PMID 32369358
Adenosine A2A receptor antagonists new 8
Paeonoside
Indisulam 165668
Design and synthesis of a highly selective EP2
Licofelone 156897
Novel antidotes for target specific oral anticoagulants PMID 26380149
BIBX 1382 dihydrochloride
The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae PMID 8649379
Trypanocidal activity of aziridinyl nitrobenzamide prodrugs PMID 20679506
Discovery of Clinical Candidate BMS
Daucosterol induces autophagic
N
4
Pimecrolimus hydrate 1000802
Myristyl stearate 17661
DMTr
PSAP/Prosaposin 蛋白, Mouse (HEK293, His)
Solvent blue 12 128
STI
5
Salvianolic Acid B Attenuates Liver Fibrosis via Suppression of Glycolysis
Identification of novel off targets of baricitinib and tofacitinib by machine learning with a focus on thrombosis and viral infection PMID 35551258
Iodofenphos 18181
MCE
MCE
MCE
MCE
Methyl 2,5
盐皮质激素
MCE
MCE
酰基辅酶 A 脱氢酶家族成员 11（ACAD11）基因
MeOSuc
Darodipine (PY 108
Microbial neutral proteinase 9068
Desmethyl Ranolazine
Chn1 Mouse Pre
MCE
ATM 丝氨酸/苏氨酸激酶（Atm）基因
与锌指结构域 1B 相邻的溴结构域（BAZ1B）基因
BMS
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019
Novel Pyridazin
AMB639752
cytokines
细胞色素 b5 还原酶 3（CYB5R3）基因
MCE
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