最近收录_第586页_生物活性分子
生物活性分子最近更新
尿嘧啶 DNA 糖基化酶（UNG）基因
In vitro activity of OPT
MCE
m6A modification negatively regulates translation by switching mRNA from polysome to P
BCL2 相互作用蛋白 2（BNIP2）基因
Advances in the discovery of exosome inhibitors in cancer PMID 32543905
Boscialin 129277
Novel inhibitors targeting the PGK1 metabolic enzyme in glycolysis exhibit effective antitumor activity against kidney renal clear cell carcinoma in vitro and in vivo PMID 38354523
A
Targeting PSMD14 combined with arachidonic acid induces synthetic lethality via FADS1 m6A modification in triple
Oxypeucedanin 737
Oroxylin A promotes PTEN
Hexadecanedioic acid
Combination of trehalose and inulin efficacy as lyoprotectant for the preservation of human monocytic cell line PMID 40795611
Lung cancer cell
LY137150 86315
Hcrtr1 Rat Pre
FNDC5 inhibits malignant growth of human cervical cancer cells via restraining PI3K/AKT pathway PMID 38558303
3′
MCE
PSORI
Dihydrospinosyn A aglycone
MCE
Tranylcypromine Based Lysine
MCE
MCE
The Akt/mTOR cascade mediates high glucose
Angiotensin II receptor type 1 blocker candesartan improves morphine tolerance by reducing morphine‑induced inflammatory response and cellular activation of BV2 cells via the PPARγ/AMPK signaling pathway PMID 36004465
MCE
肾上腺素能受体 2（ADRB2）基因
Discovery of Bi
C9 Human Pre
Nav1.7
Acetic acid
HDAC6
Naringenin Protected Against Blood Brain Barrier Breakdown after Ischemic Stroke through GSK
MCE
MCE
b
LYT100
Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells PMID 23951092
MCE
Drug repurposing An antidiabetic drug Ipragliflozin as Mycobacterium tuberculosis sirtuin
Terazosin 63590
Procoxacin bidirectionally inhibits osteoblastic and osteoclastic activity in bone and suppresses bone metastasis of prostate cancer PMID 36759880
Pavinetant 941690
Nepetoidin B, a Natural Product, Inhibits LPS
Ex vivo imaging of fatty acid amide hydrolase activity and its inhibition in the mouse brain PMID 16278311
Bepotastine besilate 190786
Urinary PGE
BAY598
Immune enhancement of nitroreductase
Boc
Isolation and Structure Elucidation of Neokadsuranic Acid A, the First Triterpenoid with the 14 (13
NSD2 modulates Drp1
AR
Droloxifene 82413
Re
cultures
4
Chemical Identity and Mechanism of Action and Formation of a Cell Growth Inhibitory Compound from Polycarbonate Flasks PMID 29516721
DMU212
Farnesyltransferase inhibitor (L
Autophagy up
LRRC8A promotes Glaesserella parasuis cytolethal distending toxin
Effects of vitamin D status on cutaneous wound healing through modulation of EMT and ECM PMID 39127309
Esculin protects human blood cells from bioallethrin
Distinct FGF
P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases PMID 24514864
Design and Synthesis of 3
Herbicide safener
Wee1/HDAC
SSR411298 666860
Clinprost 88931
TASIN
Lupiwighteone 104691
GW0742
IMM20059
Inhibition of biofilm formation by D
Development of prodrug 4
Synthesis and cytotoxic evaluation of halogenated α
MCE
ARS1620
OP
MCE
Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum PMID 26905523
Diacetolol
VS
DUB profiling
FGFR
JM
CK
depths
(E)
MCE
FGFR
Olafertinib 1660963
MCE
无名指结构域 1 细胞生长调节因子（CGRRF1）基因
S
MCE
Myostatin
MCE
FGFR
JNJ
MCE
In vivo anti
Icariin improves learning and memory function by enhancing HRD1
Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor PMID 38744281
MK4541
Burapitant
BAY
Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan
Rifapentine
PLX 4545
蛋白酶体 26S 亚基，非 ATPase 3（PSMD3）基因
Human CCL21 mRNA
Cxcl16 Rat Pre
RUVBL1/2 ATPase
6β
SM
Two widely used RSK inhibitors, BI
NRMA
Tm4sf1
Design and synthesis of highly sensitive and selective fluorescein
AG
Nociceptive
CNX774
MIV 247
B7
Galanin (1
RB
HL 435
BI 187004 1303515
NK622
circulating malignant cell
K00135
Fmoc
Quercetin inhibits the progression of endometrial HEC
12
Lavendustin B 125697
TGF
Specific antagonist of retinoid toxicity in mice PMID 8658506
Boc
The ATP
Fmoc
Anti
Volrustomig 2407760
MCE
MCE
MCE
KT
tryptophan synthase
GSK620 2088410
KRP 199
m
DMU 212
NSC 77053
XL 652
CPL 207280
E 235
MCE
MCE
GW406108X
IND 1316 1888473
MCE
JTE607
FITC
MCE
Cefovecin
MCE
MCE
PTPN1 Human Pre
Human CCL1 mRNA
ZP3 蛋白, Human (HEK293, His
MCE
MCE
MCE
Shikonin attenuates cerebral ischemia/reperfusion injury via inhibiting NOD2/RIP2/NF
MCE
Fotemustine 92118
MCE
MCE
MCE
MCE
MCE
MCE
PBI
HI 253
MCE
(2S,4R)
AGN192024
3
MCE
Corey lactone benzoate impurity 1 1215192
L
implantation
G 9791
A987306
Nonhypoglycemic drug reactions of agents used to treat diabetes PMID 11149163
TRPMPZQ
REDD1
MCE
Anti
Tubulin polymerization
Anti
GSK
MCE
2
SSR 240600
C9 Mouse Pre
heterotrimeric
Chm Rat Pre
AN
MCE
Identification of Potent, Selective, and Peripherally Restricted Serotonin Receptor 2B Antagonists from a High
Galactokinase (BiGalK) (半乳糖激酶（BiGalK）)
EphA5
H1.2 接头组蛋白，簇成员（H1
Role of autophagy in resistance to ivermectin in Haemonchus contortus PMID 39616807
MCE
MCE
Myh7 Mouse Pre
Thiol
MCE
Protease
Oral once
Remetinostat (SHP
PHC2 Human Pre
Some major mycotoxins and their mycotoxicoses
OK101
miR
Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply PMID 34265474
Biotransformation of Acetamide to Acetohydroxamic Acid at Bench Scale Using Acyl Transferase Activity of Amidase of Geobacillus pallidus BTP
ATX inhibitor 21
MCE
Tes
MCE
RS 42358
MCE
MCE
Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model PMID 22850627
rac
BHV7000
MCE
thermophilic
MCE
2,3,4,6
inflammation regulation
Spatiotemporal roles of AMPK in PARP
MCE
Coiled
Reversing anticoagulant effects of novel oral anticoagulants role of ciraparantag, andexanet alfa, and idarucizumab PMID 26937198
DC
MCE
Quercetin attenuates the symptoms of osteoarthritis in vitro and in vivo by suppressing ferroptosis via activation of AMPK/Nrf2/Gpx4 signaling PMID 39717946
XLH
IL
Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for inhibiting amyloid beta formation in silico and in vitro study PMID 27511370
Synthesis, biological evaluation and mechanistic studies of totarol amino alcohol derivatives as potential antimalarial agents PMID 22196513
Cyanine5 carboxylic acid bromide 666829
MCE
抗原 (Antigens)
MCE
AREG Human Pre
MCE
MCE
Calcein Blue AM
MCE
GAS6 蛋白, Human (HEK293, Fc)
Aurachin SS
MicroRNA‑148a inhibition protects against ovariectomy‑induced osteoporosis through PI3K/AKT signaling by estrogen receptor α PMID 29620276
MCE
C9orf78 Human Pre
D
MCE
Cbl Rat Pre
H
MCE
SS
MCE
Liarozole markedly increases all trans
Nucleotide
MC4379
The third
MCE
Fmoc
Phenethyl Benzoate
MCE
Axin2
MCE
Nybomycin
Crabp2 Mouse Pre
MCE
Npm1
argonaute RISC 催化组分 2（AGO2）基因
(20R)
PARD6A Human Pre
MCE
MCE
PF
ADP 核糖基化因子样 GTPase 2（ARL2）基因
Cxcl16 Mouse Pre
Tridecanoic acid
MCE
MCE
MCE
Ethyl stearate
MCE
Soft tissue sarcoma cells are highly sensitive to AKT blockade a role for p53
Hydroxydehydro Nifedipine Carboxylate 34783
MCE
KL373
(1S,3R)
GTx
12R,13S
2
Fos 原癌基因，AP
MCE
BCMA/TNFRSF17 蛋白, Cynomolgus (HEK293, His)
MCE
MCE
Kaitocephalin (PF1191)
6bK TFA
ACAD11 Human Pre
CHM Human Pre
Thiol
Bisnorcymserine (N1,N8
N6
MCE
JPS004
Darbufelone mesylate (Standard)
MCE
MCE
Nav1.7
URAT1 inhibitor 7
MCE
iso
MCE
MCE
2
Trans
MCE
Tetrabenazine impurity 1 99672
5α
Effects on gonadotropin secretion of 5
diABZI
Dihydro
Lipid and small
trans
Upamostat hydrogen sulfate (WX
CBA1205
Etalocib sodium (LY293111 sodium)
MCE
TCO
GX
MCE
MCE
MCE
(2S,3R)
6'
Z
L
Tpm1
Antigens
MCE
Ecallantide
SWATH
EMT inhibitor
MCE
Synthesis of licochalcone analogues with increased anti
Dose
DUBs
Identification of Small
MCE
HDAC
Nemonoxacin malate 951163
Daucosterol disturbs redox homeostasis and elicits oxidative
Neurotensin type 1 receptor
MCE
TI17
RTA
Use of the proton pump inhibitor pantoprazole to modify the distribution and activity of doxorubicin a potential strategy to improve the therapy of solid tumors PMID 24141627
MCE
Differential contribution of APP metabolites to early cognitive deficits in a TgCRND8 mouse model of Alzheimer's disease PMID 28275722
MK793
Arylpyrrolizines as inhibitors of microsomal prostaglandin E2 synthase
Targeting HER2 Exon 20 Insertion
Biotin
Hexapeptide
propargyl
Effects of a 20
4,6
Role of ABCC1 in export of sphingosine
Bisoctrizole
Atuveciclib Racemate 1414943
MCE
Lufenuron suppresses the resistance of Formosan subterranean termites (Isoptera Rhinotermitidae) to entomopathogenic bacteria PMID 24020297
Absence of an active metabolite for the triazole antifungal pramiconazole PMID 17225011
MCE
MCE
LFFAADHLV(Val
MCE
Benanomicin A 116249
SB683699
NK3201
V617F
Fluorescein
adrenergic
CDB
HKI
Involvement of CaMKII in regulating the release of diplotene
Sulfamonomethoxine
4
LAH4 184776
thrombotic disorders
RORγt
MCE
MCE
Src
MCE
Ficerafusp alfa
TAK 079
Pax3 Mouse Pre
BrTet
HDAC6
Coumarin
leukemic cell line
MCE
Tspan7
Creb1 Mouse Pre
COX2 抗体 (YA6270)（COX2 Antibody (YA6270)）
MCE
C9orf72 Mouse Pre
Ziapin
MCE
ETS 转录因子 ELK4（ELK4）基因
MCE
UVB absorber
Trimethyl chitosan
ICG acid
SKLB 325
DHFR
U 66858
Vps34
MDI 2268
HS
[D
AUDA (Standard)
KMT9
AK 102
Vicenin2
LUF5981
palm11
HDAC6
BW
Acid Red 18
L 750667
LSN 3106729
RX 518
A
Cyclic flow reductions
VU0359516
RO 0711401
CCK
Heptanedioic acid
CB 300945
Cabotegravir
Marasmic acid
Solvent blue12
Sensitive and specific LC
migraine
13
STING ligand
CB 1954
DNA crosslinker2
ONC 392
CH
The Caveolin
5
RO0270608
A 274
Z
TNFα
MU
Carboxypyridostatin 1417638
Inhibitor 1 of Protein Phosphatase 1 Regulates Ca2+/Calmodulin
Mebendazole
MCB
BVT 2733
MCE
IR 700DX 916821
USP7 protects TFEB from proteasome
Ajoene, a garlic
Albicidin 1622253
PTX80
PR
KUNB31
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