最近收录_第23页_生物活性分子
生物活性分子最近更新
Ficolin
IRDye700Dx (Maleimide)
Bioactive Constituents of Glycyrrhiza uralensis (Licorice) Discovery of the Effective Components of a Traditional Herbal Medicine PMID 26841168
Tanshinol ameliorates imiquimod
Parthenolide suppresses non
GOT2 Silencing Promotes Reprogramming of Glutamine Metabolism and Sensitizes Hepatocellular Carcinoma to Glutaminase Inhibitors PMID 35895805
Cytoplasmic binding partners of the Integrator endonuclease INTS11 and its paralog CPSF73 are required for their nuclear function PMID 39032490
Exploring the specificity of the PI3K family inhibitor LY294002 PMID 17302559
Human umbilical cord mesenchymal stem cell
Exosomes derived from baicalin
Lens epithelium cell ferroptosis mediated by m6A
Abietane
Glycogen stores mediated by the p53
Grape seed proanthocyanidins protect PC12 cells from hydrogen peroxide
CRIP1 suppresses BBOX1
Oxalate stimulates macrophage secretion of prostaglandin E2 to promote renal tubular epithelial cell osteogenesis PMID 39986650
Design and synthesis of novel oxazole containing 1,3
A novel CSN5/CRT O
FBN2 promotes the proliferation, mineralization, and differentiation of osteoblasts to accelerate fracture healing PMID 39924543
Autophagy assuages myocardial infarction through Nrf2 signaling activation
YTHDF1 promotes hepatocellular carcinoma progression via activating PI3K/AKT/mTOR signaling pathway and inducing epithelial
Activity of TP
14
Synthesis, in vitro and in vivo biological evaluation, and comprehensive understanding of structure
Antiproliferative and apoptotic effects of compounds from the flower of Mammea siamensis (Miq.) T. Anders. on human cancer cell lines PMID 23206866
Inhibition of long
A specific inhibitor of TGF
Discovery of a novel ferroptosis inducer
重组蛋白
Embryonic Stem Cells Modulate the Cancer
Synthesis of a terphenyl substituted 4
Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer PMID 34508104
Lipopolysaccharide
Splicing factor arginine/serine
Medium
E3 ligase MAEA
Bupivacaine (丁吡卡因)
Quantitative prediction of CYP2B6 induction by estradiol during pregnancy potential explanation for increased methadone clearance during pregnancy PMID 22815312
Synergism of Feeding and Digestion Regulated by the Neuropeptide F System in Ostrinia furnacalis Larvae PMID 36611986
UFMylation of HRD1 regulates endoplasmic reticulum homeostasis PMID 37795761
The oncometabolite 2
Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation
Glabridin exhibits potent inhibitory effects against Toxoplasma gondii in vitro and in vivo PMID 39695816
Methionine
ATP7B gene therapy of autologous reprogrammed hepatocytes alleviates copper accumulation in a mouse model of Wilson's disease PMID 35340061
The Main Protease of Middle East Respiratory Syndrome Coronavirus Induces Cleavage of Mitochondrial Antiviral Signaling Protein to Antagonize the Innate Immune Response PMID 38400032
Pathogenicity analysis of three SCA14
Fluid shear stress enhances natural killer cell's cytotoxicity toward circulating tumor cells through NKG2D
Licarin B ((
Bovine Endothelial cell growth supplement,suitable for cell culture (ECGS,Bovine，牛内皮细胞生长补充剂,suitable for cell culture)
Ponicidin triggered ferroptosis in esophageal squamous cell carcinoma by suppressing the SLC7A11/Glutathione/GPX4 signalling axis PMID 40456202
HA/Hemagglutinin 蛋白, Influenza B (AFP83206, HEK293, His)
Etoposide 33419
Dual Inhibition of BRAF
Metformin attenuates colitis via blocking STAT3 acetylation by reducing acetyl
Podophyllotoxin and nocodazole counter the effect of IKP104 on tubulin decay PMID 9853681
PAK1抑制剂、激活剂、基因
Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties PMID 36449385
Efficacy of ronidazole for treatment of feline Tritrichomonas foetus infection PMID 16734086
NA/Neuraminidase 蛋白, H1N1 (ABR28848, HEK293, His)
E2F2 directly regulates the STAT1 and PI3K/AKT/NF
BCL
Amsacrine hydrochloride 54301
BRAFV600E
Synthesis and Antitumor Activity of C
Lactylation of HMGB1 at K177 Drives Nuclear Export of TIAR to Promote Hypoxia
MK 733 (Standard)
Porcine Circovirus Type 2 Hijacks Host IPO5 to Sustain the Intracytoplasmic Stability of Its Capsid Protein PMID 36409110
Molecular design, chemical synthesis, and biological evaluation of '4
Compensatory reactions of B cells in response to chronic HIV
Pharmacological inhibition of SREBP1 suppresses pancreatic cancer growth via inducing GPX4
Corticotropin
Effect of doramectin on programmed cell death pathway in glioma cells PMID 37084153
4
Enhanced ferroptosis sensitivity promotes the formation of highly myopic cataract via the DDR2
Current status of carbazole hybrids as anticancer agents PMID 34838335
Design, synthesis and molecular docking studies of novel N
Cefotaxime
Inhibition of cannabinoid receptor type 1 sensitizes triple
MOF negatively regulates estrogen receptor α signaling via CUL4B
Discovery and structure
Peptidase inhibitor 16 promotes inflammatory arthritis by suppressing Foxp3 expression via regulating K48
The Prostaglandin E2 Receptor EP4 Promotes Vascular Neointimal Hyperplasia through Translational Control of Tenascin C via the cAPM/PKA/mTORC1/rpS6 Pathway PMID 36078128
Application of the newer corticosteroids to augment diuresis in congestive heart failure PMID 13520608
Gadolinium deposition in the liver and brain in a rat model with liver fibrosis after intravenous administration of gadoxetate disodium PMID 38545226
Using Metal
Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis PMID 22895560
An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator
New antitumor substances, FR901463, FR901464 and FR901465. I. Taxonomy, fermentation, isolation, physico
细胞器研究
Imazamox (Standard) (CL29926 (Standard)，甲氧咪草烟 (标准品))
Construction of anti
Effects of Artemisia annua L. Essential Oil on Osteoclast Differentiation and Function Induced by RANKL PMID 35432559
Dichotomine B
Discovery and Rational Design of Pteridin
Loss of CDKN2A Enhances the Efficacy of Immunotherapy in EGFR
Phenylimino
Initial testing (stage 1) of BAL101553, a novel tubulin binding agent, by the pediatric preclinical testing program PMID 25407467
Mechanism of miR
STAM2
Synthesis and antitumor activities of novel α
Uric acid (Standard) (尿酸 (Standard))
DC
PI3K/AKT/p53 pathway inhibits infectious spleen and kidney necrosis virus infection by regulating autophagy and immune responses PMID 34968710
A novel epigenetic drug conjugating flavonoid and HDAC inhibitor confer suppression of acute myeloid leukemogenesis PMID 34282832
Reduced iron bioavailability drives acute high‑altitude lung injury through HIF1α activation and mitophagy PMID 40444479
Puerarin pretreatment provides protection against myocardial ischemia/reperfusion injury via inhibiting excessive autophagy and apoptosis by modulation of HES1 PMID 39755744
KLF4 down
3
Benzothienoquinazolinones as new multi
The new mitochondrial uncoupler BAM15 induces ROS production for treatment of acute myeloid leukemia PMID 35192847
Skeletal muscle HSF1 prevents insulin resistance by improving glucose utilization PMID 36421020
Triptolide Improves Cognitive Dysfunction in Rats with Vascular Dementia by Activating the SIRT1/PGC
SP1
PARK7 deficiency inhibits fatty acid β
Macrophage fusion event as one prerequisite for inorganic nanoparticle
MSCs promote the efferocytosis of large peritoneal macrophages to eliminate ferroptotic monocytes/macrophages in the injured endometria PMID 38693589
Morin ameliorates coronary artery relaxation by activating TRPV4
Chaperone
Progranulin Promotes the Formation and Development of Capsules Caused by Silicone in Sprague
Synthesis and biological evaluation of paclitaxel and vorinostat co
Annulation of substituted anthracene
Iloprost Concentration
Resveratrol protects against deoxynivalenol
Microglial BDNF modulates arketamine's antidepressant
Antifungal Activity of the Lipophilic Antioxidant Ferrostatin
Targeting ABCD1
Premature termination codon readthrough in Drosophila varies in a developmental and tissue
RNA m6A methylation modulates airway inflammation in allergic asthma via PTX3
Dihydroartemisinin Sensitizes Lung Cancer Cells to Cisplatin Treatment by Upregulating ZIP14 Expression and Inducing Ferroptosis PMID 39394878
Exploring Derivatives of Quinazoline Alkaloid l
Saxagliptin alleviates erectile dysfunction through increasing stromal cell
Cyclo(RGDyC) TFA
A 18β
Heparin sodium salt (Sodium heparin，肝素钠)
Neuroprotection of N
Trace amine
Targeting prominin
Benztropine (Benzatropine)
Distinct types of intramitochondrial protein aggregates protect mitochondria against proteotoxic stress PMID 38551959
Long Non
Effects of the pan
Kindlin
A Recombinant Parathyroid Hormone
Human PAX2 mRNA
Human GATA4 mRNA
Isoorientin Attenuates Cisplatin
P
Mitochondrial dysfunction
Angiotensin
Chelating 琼脂糖 (IDA) 6FF (Chelating Agarose (IDA) 6FF)
Addressing Clinical Limitations of Glutaminase Inhibitors Novel Strategies for Osimertinib
Design, synthesis and evaluation of novel hybrids between 4
miR
Depatuxizumab MMAE
Zebrafish phd3 Negatively Regulates Antiviral Responses via Suppression of Irf7 Transactivity Independent of Its Prolyl Hydroxylase Activity PMID 32669312
Ginsenoside Rg3 promotes regression from hepatic fibrosis through reducing inflammation
Jolkinolide B sensitizes bladder cancer to mTOR inhibitors via dual inhibition of Akt signaling and autophagy PMID 34798195
N
PT 2399
MiR
Gastrin I, human
Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis PMID 36064453
DNA
Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys PMID 39143064
Benzoylaconitine A promising ACE2
Inhibition of Mitochondrial Succinate Dehydrogenase with Dimethyl Malonate Promotes M2 Macrophage Polarization by Enhancing STAT6 Activation PMID 39806091
7
Quercetin Confers Protection against Sepsis
Comparative in
Duck House Inhalable Particulate Matter Induces Lung Injury by Activating Ferroptosis PMID 40403547
Juvenile hormone and BMP signaling modulate fat body cell fate during the transition of previtellogenic development to vitellogenesis PMID 40437481
Lipocalin
Tropolones as lead
Establishment of an acquired lorlatinib
N6
Irisin protects against vascular calcification by activating autophagy and inhibiting NLRP3
Deactylation by SIRT1 enables liquid
Quercetin Alleviates Acrylamide
From Gene to Intervention NLRC4 and WIPI1 Regulate Septic Acute Lung Injury Through Autophagy PMID 40093959
ZBTB7C m6A modification incurred by METTL3 aberration promotes osteosarcoma progression PMID 37121538
RAB39B Deficiency Impairs Learning and Memory Partially Through Compromising Autophagy PMID 33364235
Development of novel ferulic acid derivatives as potent histone deacetylase inhibitors PMID 24095016
Insulin/IGF signaling and TORC1 promote vitellogenesis via inducing juvenile hormone biosynthesis in the American cockroach PMID 33097549
Blueberry anthocyanin extracts protect against Helicobacter pylori
Brompheniramine maleate (Standard) ((±)
Integrating metagenomics with metabolomics for gut microbiota and metabolites profiling in acute pancreatitis PMID 39277616
High concentration of estrogen resulted by COH may affect the secretion of pro
Phosphorylation of LZTS2 by PLK1 activates the Wnt pathway PMID 38740232
Synthesis and biological evaluation of moxifloxacin
Targeting ST8SIA6
The deubiquitinating enzyme USP19 facilitates hepatocellular carcinoma progression through stabilizing YAP PMID 37832781
CCL26 is upregulated by nab
PI3K/mTOR inhibitors promote G6PD autophagic degradation and exacerbate oxidative stress damage to radiosensitize small cell lung cancer PMID 37802999
USP16 counteracts mono
TGF
Dynamic altruistic cooperation within breast tumors PMID 38093346
鞘内注射
HA/Hemagglutinin 蛋白, H3N2 (ACN50256, sf9)
Discovery and investigation of antiproliferative and apoptosis
David vs. Goliath The Structure, Function, and Clinical Prospects of Antibody Fragments PMID 31544834
Pien
CC 基序趋化因子受体 8（CCR8）基因
Iron deficiency
MG
THEM6 modulates carboplatin sensitivity by regulating ferroptosis through FDFT1 in triple
Diuretic effect of nitrendipine contributes to its antihypertensive efficacy a review PMID 2468846
A fast and efficient method for isolating Schwann cells from sciatic nerves of neonatal mice PMID 34752812
Puerarin Alleviates Cerebral Ischemia
MCI
Certepetide 2580154
Neferine Protects against Hypoxic
JOSD1 inhibits mitochondrial apoptotic signalling to drive acquired chemoresistance in gynaecological cancer by stabilizing MCL1 PMID 31043700
Self
Ano5 deficiency disturbed bone formation by inducing osteoclast apoptosis in Gnathodiaphyseal dysplasia PMID 40049314
Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer's disease model PMID 34116709
A randomised trial of a pre
Synthesis and in vitro antimalarial testing of neocryptolepines SAR study for improved activity by introduction and modifications of side chains at C2 and C11 on indolo[2,3
Grass carp Il
Elevated SLC3A2 Expression Promotes the Progression of Gliomas and Enhances Ferroptosis Resistance through the AKT/NRF2/GPX4 Axis PMID 40083086
Valproic acid sodium (Sodium Valproate，丙戊酸钠)
Interplay between autophagy and Sindbis virus in cells derived from key arbovirus vectors, Aedes albopictus and Aedes aegypti mosquitoes PMID 34826589
BET
Adiponectin Alleviates Diet
Polyoxypregnane steroids from the stems of Marsdenia tenacissima PMID 25215856
Baicalein ameliorates cognitive impairment of vascular dementia rats via suppressing neuroinflammation and regulating intestinal microbiota PMID 38295883
2
CDKL5 deficiency in adult glutamatergic neurons alters synaptic activity and causes spontaneous seizures via TrkB signaling PMID 37777961
UCHL1 contributes to insensitivity to endocrine therapy in triple
A targetable antioxidant defense mechanism to EZH2 inhibitors enhances tumor cell vulnerability to ferroptosis PMID 40229247
DSPE
Novel Function of lncRNA ADAMTS9
Arimistane Degradation product or metabolite of 7
Epigenetically silenced KAT2B suppresses de novo lipogenesis through destroying HDAC5/LSD1 complex assembly in renal cell carcinoma PMID 40784518
Mercury dibromofluorescein disodium
ATTO 488 carboxylic acid
JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation PMID 33442397
Scabertopin Derived from Elephantopus scaber L. Mediates Necroptosis by Inducing Reactive Oxygen Species Production in Bladder Cancer In Vitro PMID 36497458
A role of STING signaling in obesity
The cumulative antitumor effects of regorafenib and radiotherapy in hepatocellular carcinoma PMID 38837427
Investigation of thiazolyl
Correction The Nedd8
Epigenetically upregulating TROP2 and SLFN11 enhances therapeutic efficacy of TROP2 antibody drug conjugate sacitizumab govitecan PMID 37567892
Mastoparan M promotes functional recovery in stroke mice by activating autophagy and inhibiting ferroptosis PMID 38583338
Colorectal cancer inhibition by BET inhibitor JQ1 is MYC
Asiaticoside attenuates bleomycin
Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco
Protective Effects of Oroxylin A against Doxorubicin
Characterization of the Inducible and Slow
Caffeic acid phenethyl ester protects renal tubular epithelial cells against ferroptosis in diabetic kidney disease via restoring PINK1
Pitavastatin Calcium Confers Fungicidal Properties to Fluconazole by Inhibiting Ubiquinone Biosynthesis and Generating Reactive Oxygen Species PMID 38929106
Cisplatin and temozolomide combinatorial treatment triggers hypermutability and immune surveillance in experimental cancer models PMID 40513578
Thiostrepton induces ferroptosis in pancreatic cancer cells through STAT3/GPX4 signalling PMID 35859150
Pentagastrin gastroprotection against acid is related to H2 receptor activation but not acid secretion PMID 9863477
Mutation
Guanylate cyclase
Cholesterol inhibits autophagy in RANKL
GMP Glypican
Excess KLHL24 impairs skin wound healing by degradation of vimentin PMID 36716923
Candesartan Cilexetil
KK
2
N
Lactobacillus fermentum Postbiotic
Upregulation of CYR61 by TGF
Cellular RNA
Polymerase Acidic Protein
Speedy A governs non
SARS
SAMβA TFA
Benzyladenine (Standard)
COX
N
Renal and femoral venous blood flows are regulated by different mechanisms dependent on α
The NP protein of Newcastle disease virus dictates its oncolytic activity by regulating viral mRNA translation efficiency PMID 38377149
Tumor necrosis factor α
Cardamonin, a Novel Antagonist of hTRPA1 Cation Channel, Reveals Therapeutic Mechanism of Pathological Pain PMID 27589700
Exogenous carbon monoxide promotes GPX4
KDM6B regulates M2 polarization of macrophages by modulating the stability of nuclear β
Oxidized
Gold nanoparticles
O
Regulation of cancer cell ferroptosis by PTRF/Cavin
C
FITC
Genistein 7
NSC 357754
An actin bracket
Endothelial senescence induced by PAI
Embryonic 6 2 FTOH exposure causes reproductive toxicity by disrupting the formation of the blood
细胞粘附分子 5 (CEACAM
Toxic effects of hexaflumuron on the development of Coccinella septempunctata PMID 23917742
ETV7 regulates breast cancer stem
2
Circadian rhythm
AMG
Molecular and cellular effects of azilsartan a new generation angiotensin II receptor blocker PMID 21986624
Filricianine sodium
Exercise promotes skeletal muscle growth in adolescents via modulating Mettl3
Ubiquitination of ALOX15 regulates endoplasmic reticulum stress in Schwann cells and experimental autoimmune neuritis (EAN) models PMID 40222426
Orphan nuclear receptor NUR77 relieves insulin resistance in HTR
Phenotypic rescue via mTOR inhibition in neuron
Unraveling the crucial role of SDF
Design, synthesis and biological evaluation of 1,3
XE991 dihydrochloride
Exploring the target scope of KEAP1 E3 ligase
Dobutamine increases alveolar liquid clearance in ventilated rats by beta
Epimedin B protects against bone loss and inflammation in diabetic osteoporosis rats by regulating OPG/RANKL pathway PMID 40264188
METTL3 and IGF2BP2 coordinately regulate FOSL1 mRNA via m6A modification, suppressing trophoblast invasion and contributing to fetal growth restriction PMID 39565355
Oxidative stress promotes lipid
Chemical constituents of Brazilian propolis and their cytotoxic activities PMID 9677271
Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents PMID 31972391
Single
PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C PMID 37682709
Nuclear to Cytoplasmic Transport Is a Druggable Dependency in HDAC7
Bacillus siamensis Targeted Screening from Highly Colitis
1
SAR refinement of antileishmanial N(2),N(4)
The prognostic gene CRABP2 affects drug sensitivity by regulating docetaxel
Hemorrhagic shock and reperfusion induced cognitive impairment through HIF3α/SIRT1 PMID 40819662
Asymmetric synthesis and anti
Inhibitions and Down
Inhibition of aortic CX3CR1+ macrophages mitigates thoracic aortic aneurysm progression in Marfan syndrome in mice PMID 39817456
The Proteasome Inhibitor Marizomib Evokes Endoplasmic Reticulum Stress and Promotes Apoptosis in Human Glioblastoma Cells PMID 39204194
SLC31A1 promotes chemoresistance through inducing CPT1A
Olive Pomace Extract Acts as a New Potent Ferroptosis Inhibitor in Human Cells PMID 40807270
Design, synthesis, and biological evaluation of β
The discovery of novel antitrypanosomal 4
MiR
Accelerated Wound Healing and Keratinocyte Proliferation through PI3K/Akt/pS6 and VEGFR2 Signaling by Topical Use of Pleural Fluid PMID 35269438
Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma PMID 32699265
High‑throughput screening identification of a small‑molecule compound that induces ferroptosis and attenuates the invasion and migration of hepatocellular carcinoma cells by targeting the STAT3/GPX4 axis PMID 36825585
A Selective Small
The role of peripheral serotonin and norepinephrine in the gastroprotective effect against stress of duloxetine PMID 36627097
Antimalarial Oxoprotoberberine Alkaloids from the Leaves of Miliusa cuneata PMID 26928423
Metformin promotes microglial cells to facilitate myelin debris clearance and accelerate nerve repairment after spinal cord injury PMID 34480113
Evaluation of In Vitro Distribution and Plasma Protein Binding of Selected Antiviral Drugs (Favipiravir, Molnupiravir and Imatinib) against SARS
Monochromatic Light Pollution Exacerbates High
FABP4
LINC00470 Coordinates the Epigenetic Regulation of ELFN2 to Distract GBM Cell Autophagy PMID 30037656
Boningmycin induces AMPK
Simulation of multiple ion channel block provides improved early prediction of compounds' clinical torsadogenic risk PMID 21300721
RAPTOR promotes colorectal cancer proliferation by inducing mTORC1 and upregulating ribosome assembly factor URB1 PMID 31886628
酶联免疫吸附测定
Pharmacological properties of droxicam, a new non
SHMT2 regulates CD8+ T cell senescence via the reactive oxygen species axis in HIV
AdipoRon Alleviates Free Fatty Acid
Effects of pentolinium on blood sugar and serum potassium concentrations during anaesthesia and surgery PMID 1218171
The anticancer drug ellipticine activated with cytochrome P450 mediates DNA damage determining its pharmacological efficiencies studies with rats, Hepatic Cytochrome P450 Reductase Null (HRN™) mice and pure enzymes PMID 25547492
Heat shock protein A1L restricts influenza A virus by ubiquitination of NA PMID 40788012
RORγt agonist LYC
Delta
A Broad Anti
SS47 TFA
SUMO1 Modification Facilitates Avibirnavirus Replication by Stabilizing Polymerase VP1 PMID 30842328
Discovery of a novel highly potent and low
Pharmaceutical inhibition of BCL6 ameliorates resistance to imatinib in chronic myeloid leukemia PMID 39258188
JNK3 inhibitor
P7C3 Inhibits LPS
Autophagy mediates free fatty acid effects on MDA
Induction of cell cycle arrest at G1 and S phases and cAMP
Detailed mechanistic analysis of gevokizumab, an allosteric anti
(
A novel cryopreservation solution for adipose tissue based on metformin PMID 39849625
Identification of Thieno[3,2
MIR937 amplification potentiates ovarian cancer progression by attenuating FBXO16 inhibition on ULK1
Polyphyllin I Inhibits the Metastasis of Cervical Cancer Through the Regulation of the β
Sex differences in the metabolic activation of and platelet response to vicagrel in mice Androgen as a key player PMID 39366431
A Combined Model of Human iPSC
Scopolamine
Centipeda minima extracts and the active sesquiterpene lactones have therapeutic efficacy in non
Research for a Common Thread Insights into the Mechanisms of Six Potential Anticancer Agents PMID 40076255
Trastuzumab duocarmazine ((vic)
A potent GPX4 degrader to induce ferroptosis in HT1080 cells PMID 38194774
UBE2C promotes LUAD progression by ubiquitin
Alisol B blocks the development of HFD
Fluo
Tumor
Design, synthesis, and biological evaluation of novel histone deacetylase 1 inhibitors through click chemistry PMID 23601706
SET8, a novel regulator to ameliorate vascular calcification via activating PI3K/Akt mediated anti
Antitumor Efficacy of Focused Ultrasound
Telmisartan anti
Targeting to Intensify M2 Macrophage Polarization Ameliorate Podocyte Lipid Accumulation and Damage by Tea Polyphenols via Activating SIRT1 in the Aged Model Rats With DKD PMID 40801050
Bactericidal and anti
Discovery of small
Dopamine receptor D2 regulates GLUA1
Tamoxifen inhibits cell proliferation by impaired glucose metabolism in gallbladder cancer PMID 31782270
Dexmedetomidine postconditioning attenuates myocardial ischemia/reperfusion injury by activating the Nrf2/Sirt3/SOD2 signaling pathway in the rats PMID 36738240
Design, synthesis and antitumor evaluation of new 1,8
FTO is required for myogenesis by positively regulating mTOR
1
Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer PMID 38195593
Realistic Nanoplastics Induced Pulmonary Damage via the Crosstalk of Ferritinophagy and Mitochondrial Dysfunction PMID 38869479
A genome
The discovery and development of belimumab the anti
SETD2 epidermal deficiency promotes cutaneous wound healing via activation of AKT/mTOR Signalling PMID 33949020
GSTP1 蛋白, Human (His)
Piperine induces autophagy of colon cancer cells Dual modulation of AKT/mTOR signaling pathway and ROS production PMID 38968770
Pyrazomycin B isolation and characterization of an
co
Novel polyamine
LIPUS
(
Repurposing Oxiconazole against Colorectal Cancer via PRDX2
Intermittent heat stress facilitates the autophagy and apoptosis of the vascular endothelium in spontaneously hypertensive rats via the AMPK/mTOR/ULK1 pathway PMID 40784609
Repurposing cabozantinib to GISTs Overcoming multiple imatinib
CLK抑制剂、基因
Asiatic acid inhibits osteosarcoma cell migration and invasion via the AKT/Sp1/MMP1 axis PMID 38567545
Isorhamnetin suppresses the epithelial
Dehydroepiandrosterone attenuates LPS
Mechanism of action and cardiotonic activity of a new phosphodiesterase inhibitor, the benzimidazole derivative adibendan (BM 14.478), in guinea
Osthole pretreatment alleviates TNBS
Vinblastine sulfate 143
Single cell RNA sequencing reveals the role of local renin
SARS
Hdac3
Role of DEP domain
45 kcal% High Fat Diet
4
Machine Learning
Hypericin impedes M2 macrophage polarization and protects against Hepatocellular carcinoma PMID 40153953
Ferritinophagy
Inhibition of NF
Metabolic Profiling Reveals an Abnormal Pattern of Serum Fatty Acids in MRL/lpr Mice Under Treatment With Prednisone PMID 32158392
(S)
Methylprednisolone aceponate (Standard) (ZK 91588 (Standard))
Novel indoline
(±)
Apstatin TFA
Huc
ML385 increases ferroptosis via inhibiting Nrf2/HO
Kaempferol attenuates doxorubicin
FLI1 Induces Plaque Psoriasis and Its Inhibition Attenuates Disease Progression PMID 40129872
Optimizing drug sensitivity assays in patient
Refined high
FGFR2
Riociguat
The neem limonoids azadirachtin and nimbolide induce cell cycle arrest and mitochondria
BMSCs
ZNF480 Accelerates Chemotherapy Resistance in Breast Cancer by Competing With TRIM28 and Stabilizing LSD1 to Upregulate the AKT
6
Adrenomedullin (16
Ferroptosis inhibition attenuates inflammatory response in mice with acute hypertriglyceridemic pancreatitis PMID 37124891
SOCS2 inhibits the tumorigenesis of GISTs and increases the sensitivity of GISTs to imatinib by suppression of KIT activation PMID 39922931
Plm IV inhibitor
An HMGA2
Effects of adrenomedullin and its fragment 22
Combined inhibition of the EGFR/AKT pathways by a novel conjugate of quinazoline with isothiocyanate PMID 27135370
Activation of anti
基于电泳迁移率的实验方法
Diallyl Disulfide Induces Apoptosis and Autophagy in Human Osteosarcoma MG
KSHV RTA antagonizes SMC5/6 complex
HIV protease
Taurine Alleviates Ferroptosis
Human NFKB1 mRNA
The protective effects of memantine against inflammation and impairment of endothelial tube formation induced by oxygen
IL
Cryptotanshinone alleviates chemotherapy
A convenient synthesis of lubeluzole and its enantiomer evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells PMID 23886686
Comparability of Raman Spectroscopic Configurations A Large Scale Cross
Biotin
Poly
USP48 蛋白, Human (sf9, FLAG)
Forskolin carbamates binding and activation studies with type I adenylyl cyclase PMID 8709105
Potential detoxification effect of active ingredients in liquorice by upregulating efflux transporter PMID 30668338
ASPM Promotes the Progression of Anaplastic Thyroid Carcinomas by Regulating the Wnt/ β
(±)
Cytotoxic lanostanes from fruits of Garcinia wallichii Choisy (Guttiferae) PMID 27793565
Superoxide Dismutase
Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine PMID 19606902
Inorganic arsenic induces pyroptosis and pancreatic β cells dysfunction through stimulating the IRE1α/TNF
New active drugs against liver stages of Plasmodium predicted by molecular topology PMID 18212104
P
Promoting AMPK/SR
Engineered model of heart tissue repair for exploring fibrotic processes and therapeutic interventions PMID 39266508
Matairesinol ameliorates experimental autoimmune uveitis by suppression of IRBP
RHOA Loss of Function Impairs the IFNγ Response and Promotes CD19 Antigen Escape to Drive CAR
Two novel cytotoxic benzofuran derivatives from Brazilian propolis PMID 11000036
Absorption and transport mechanism of colloidal nanoparticles (CNPs) in lamb soup based on Caco
Minocycline attenuates ischemia
m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells PMID 31983283
anti
Ferrostatin
反向 Ras 招募系统
Bemoradan 112018
FOXP4
An immunostimulatory liponanogel reveals immune activation
AMPK activator 6
Silencing Tautomerization to Isolate Unstable Physalins from Physalis minima PMID 35608269
Design, synthesis and biological evaluation of N
LATS
Small molecules promote CRISPR
Verbena Attenuates Adriamycin
Inhibition of LDHB triggers DNA damage and increases cisplatin sensitivity in pleural mesothelioma PMID 40790017
Glycyrol alleviates osteoporosis through dual modulation on osteoclastogenesis and osteogenesis by targeting Syk signaling pathway PMID 39939034
Exogenous H2S targeting PI3K/AKT/mTOR pathway alleviates chronic intermittent hypoxia
Anhydroicaritin improves diet
O
CD30/TNFRSF8 蛋白, Human (HEK293, His)
Inhibition of RKIP aggravates thioacetamide
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