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MCE
Idasanutlin
Discovery of 4
Garetosmab 2097125
4
FBXO31 is upregulated by METTL3 to promote pancreatic cancer progression via regulating SIRT2 ubiquitination and degradation PMID 38216561
ZY2
Atrial natriuretic factor (1
Ethamsylate (Standard) (Etamsylate (Standard)，酚磺乙胺 (标准品))
Inhibition of THP
A novel GARP humanized mouse model for efficacy assessment of GARP
Fmoc
1,3
SETDB1
Co
Q8
3
Development and structure
BI2536
异罗汉松脂苷
NRG1
RNA enzyme
4
1
RNA
Ansuvimab First Approval PMID 33751449
聚
Desmedipham (Standard) (甜菜安 (Standard))
1
4β,12
JNJ
D
CHMFL
CD45
(S,R,S)
sGC activator 2
Mesulfenfos
GW
15 0 Lyso PE
Ketoconazole
Soretolide 130403
YK11
ALN
IL
PD146176 (NSC168807)
10
Integrative cardiovascular actions of a novel catecholamine, GP
Monomethyl Dolastatin 10
Ethyl phenylglyoxylate (Ethyl benzoylformate)
腺苷 3′
对羟基苯甲醛 <sup>13</sup>C
Natural Products Discovered in a High
Cadralazine (Standard)
4
Antitumor agent181
(2S,3S)
GANT 58 64048
H
MRGPRX1 Human Pre
北美黄连次碱盐酸盐
4& 039;
Thonningianin A
Yadanzioside C 95258
Fluvoxamine
PF
PGRMC1 抗体 (YA3488)（PGRMC1 Antibody (YA3488)）
盐酸肼苯哒嗪
The modification of ferroptosis and abnormal lipometabolism through overexpression and knockdown of potential prognostic biomarker perilipin2 in gastric carcinoma PMID 31520166
Exploring host epigenetic enzymes as targeted therapies for visceral leishmaniasis in silico design and in vitro efficacy of KDM6B and ASH1L inhibitors PMID 38522046
receptor for advanced glycation end products
XNW 4107
GLYAT Human Pre
recycling
Athrombine
IIIM
(S,S)
DMT
SB
Cycloartenol (Standard) (环阿屯醇 (Standard))
Diclofenac metabolite
Nor neostigmine
CD84/SLAMF5 蛋白, Mouse (HEK293, His)
Cxcl14
Abiraterone acetate (Standard)
Aspartame 22839
HNSCC
Escin Ia suppresses the metastasis of triple
Benzyltrimethylammonium tetrachloroiodate
The immunomodulatory drugs lenalidomide and pomalidomide enhance the potency of AMG 701 in multiple myeloma preclinical models PMID 32898244
KGF
FGFR
Anthraquinone
DUSP5 promotes osteogenic differentiation through SCP1/2
DA 4626
Sulphadimethoxine
TC 14012
BMS
Upregulation of secreted phosphoprotein 1 affects malignant progression, prognosis, and resistance to cetuximab via the KRAS/MEK pathway in head and neck cancer PMID 32805066
Conglobatin B1
EPZ033294
GABARAP 抗体 (YA423)（GABARAP Antibody (YA423)）
2,6
SL agonist1
SNS
Luminacin F
正庚醇
3
3
Valproic acid
2
邻乙氧基苯甲酰胺(Standard)
Antimalarial agent3
CIBA
Pentane
Myricetin 3
HPLC
4
IBS008738
Casirivimab
1
YM
Seph
四螨嗪 (Standard)
Anticancer agent
Arginase
Destomycin A
8
Spebrutinib
orthosteric and allosteric ligands
Cap B (Acetonitrile/N
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1 PMID 19161278
BNT411
Loratadine and analogues discovery and preliminary structure
Isradipine 75695
FLT3 蛋白, Human (HEK293, hFc, solution)
Codrug Approach for the Potential Treatment of EML4
LX4211 increases serum glucagon
Poly(ethylene glycol) dibenzoate (MW 410) 9004
Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine PMID 28389275
TrkC 蛋白, Mouse (HEK293, His)
New organoselenides (NSAIDs
IEIK 13
Discovery of 4
Synthesis and biological evaluation of imidazo[1,2
Favipiravir and Ribavirin protect immunocompetent mice from lethal CCHFV infection PMID 37611878
Design, synthesis, biological evaluation and molecular docking study of novel thieno[3,2
Technical Support
Structure based drug design of crizotinib (PF
Tns4 Mouse Pre
Guanylyltransferase (鸟苷酸转移酶)
G6P
6
Tris(pentafluorophenyl)phosphine (三(五氟苯基)膦)
Molecular docking studies and in vitro screening of new dihydropyridine derivatives as human MRP1 inhibitors PMID 21530277
Azido
2
Epicillin
Design, synthesis and antiproliferative activity evaluation of a series of pyrrolo[2,1
ARP
lamprey
MBD3 抗体 (YA1695)（MBD3 Antibody (YA1695)）
LULAYUGMBFYYEX
PD
Analogue based drug design, synthesis, molecular docking and anticancer evaluation of novel chromene sulfonamide hybrids as aromatase inhibitors and apoptosis enhancers PMID 27770735
RL
3
NSC308848
rac
MKN1 cell
依贝沙坦
MDR1
CMPD167
DMABA NHS ester
Mvt
CysOx2
LAIR
CD19 蛋白, Human (CHO, His)
Leucomycin A6
Plasnwdium falciparum
Phenylethanolamine A
Inosine
EIDD 2801
FAK
Azido
杧果提取物 (Mangifera indica Linn.)
NSC 369397
Higenamine
MK
4& 039;
INO80 Human Pre
Panosialin D
FK 1052
NH2
Tetrahydroisoquinolines
OICR12694 (JNJ
8β
Discovery of indazole ethers as novel, potent, non
苯叉酞酐
OPC 3689
FTO
Discovery of PH
SDF
Cefaclor monohydrate (Standard)
Discovery of fruquintinib, a potent and highly selective small molecule inhibitor of VEGFR 1, 2, 3 tyrosine kinases for cancer therapy PMID 25482937
Development of NAFLD
Pan02 tumor
Pyridoxylamine (Standard)
cardiovascular disorder
HLA
BMY
1,5
Tyrosol and hydroxytyrosol derivatives as antitrypanosomal and antileishmanial agents PMID 27155468
prodrug
Sulfo Cy5.5
COX
cationic charged quencher
BMS
ARRY
Synthesis and structure
DUR928
CaMKII delta/CAMK2D 蛋白, Human (sf9, GST)
脂多糖
Acibenzolar
Neomycin B
The selective PPARgamma antagonist GW9662 reverses the protection of LPS in a model of renal ischemia
Evidence that the domesticated fungus Leucoagaricus gongylophorus recycles its cytoplasmic contents as nutritional rewards to feed its leafcutter ant farmers PMID 37715276
aPKC
BDNF
Candesartan
DSPE
TGFBR2/TGF
燕麦提取物 (Avena sativa Linn.)
Astragaloside IV potentiates cisplatin sensitivity in triple
M
3
Discovery of targeting USP10
Ethyl erucate
1,7
Avenciguat (BI
PF 4878691
(S)
TNF RII/TNFRSF1B 蛋白, Human (Biotinylated, HEK293, Fc
Energy competition remodels the metabolic glucose landscape of psoriatic epidermal cells PMID 38855186
玉米烯酮
PF
Zanthoxylum bungeanum
MCE
MCE
N
Bad
DChemsPC 1155878
InhA inihibitor
Caramiphen, iodocaramiphen and nitrocaramiphen are potent, competitive, muscarinic M1 receptor
Riodipine
Synthesis and biological activities of (R)
Capillarisin exerts antiasthmatic activity in neonatal rats via modulating the matrix remodeling PMID 33612476
Acid
1
Shegansu B
d
Inhibitory Effect of 1
ATTO 550 cadaverin
Serpin A10 蛋白, Human (HEK293, His)
Icosyl tetradecanoate
CXCL15/Lungkine has suppressive activity on proliferation and expansion of multi
Murine primary neurons
M 2060
mTOR inhibition reprograms cellular lipid homeostasis by inducing alternative lipid uptake and promoting cholesterol transport PMID 40972529
Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat PMID 15978575
Cardioprotection with forsythoside B in rat myocardial ischemia
Kurchessine
(25S)
YHO13351
Design and Optimization of Selectivity
HNRNPC modulates PKM alternative splicing via m6A methylation, upregulating PKM2 expression to promote aerobic glycolysis in papillary thyroid carcinoma and drive malignant progression PMID 39380010
Rubia podantha
Antibacterial agent 188
Pde4b
Calcium green
A practical synthesis of chiral tricyclic cyclopenta[b]benzofuran, a key intermediate of Beraprost PMID 27461927
Citrus limonia
Cichorium intybus
Clopipazan
Pyridindolol K 2
10α
Application of the 6
Ace
Bilastine and the central nervous system PMID 22185045
Synthesis of novel 4'
Selenoethionine 2578
Secretion of miRNA
Oligopeptide 41
opioid antagonist
Site
The use of ferret trachea organ cultures for therapeutic studies of anti
CLEC2B 蛋白, Human (HEK293, Fc)
Type I Collagen, T Cell Grade, from Chick
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine β
Tristin 139101
A fluorogenic histone deacetylase assay well suited for high
RAB11A，成员 RAS 致癌基因家族（RAB11A）基因
ubiquitin
Delivery of 5
PTK 787
Mode of action of the antimicrobial compound 5
LAE 102
MCE
Gardenia
SHP2 its association and roles in systemic lupus erythematosus PMID 37351631
Hydrogenated Diglucose Detergents for Membrane
Indole derivatives sustain embryonic stem cell self
NNC 63
呋霜灵 (Standard)
Tamarixetin 603
Identification and Validation of Carbonic Anhydrase II as the First Target of the Anti
P60v
ODM
NRAS Status Determines Sensitivity to SHP2 Inhibitor Combination Therapies Targeting the RAS
Lanopylin B1
Lithospermic acid (Standard)
Pathway
sarcomeric tropomyosin
LEE011 (Standard)
WR 228258
Methyl cinnamate (Standard)
咪鲜胺
Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD
Pharmacodynamic response and inhibition of growth of human tumor xenografts by the novel histone deacetylase inhibitor PXD101 PMID 12939461
2,3
Antibiotic TS 885
In Vitro Antiviral Activity and Resistance Profile of the Next
salicylate hydroxylase
BTS40542
Myofibroblast matrix metalloproteinases activate the neutrophil chemoattractant CXCL7 from intestinal epithelial cells PMID 16401476
In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid PMID 23609606
Human alpha2,3
Ras Pathway Activation and MEKi Resistance Scores Predict the Efficiency of MEKi and SRCi Combination to Induce Apoptosis in Colorectal Cancer PMID 35326598
cholinergic system
HIV
JAK
DUSP2 affects bladder cancer prognosis by down
Novel fungal phenylpyruvate reductase belongs to d
D
LTGO
(1R,2R)
Chlorovaltrate K
Triterpenoid saponins from Xanthoceras sorbifolia Bunge and their inhibitory activity on human cancer cell lines PMID 22801644
Dectin
Uredofos 52406
NETs induce persistent lung tissue damage via thromboinflammation without altering virus resolution in a mouse coronavirus model PMID 37748582
BAY 41
A retro
exo
Fatostatin delayed lip sensory recovery after inferior alveolar nerve transection by inhibiting sterol regulatory element
Antitumor agent 180
Exploiting mixtures of H2, CO2, and O2 for improved production of methacrylate precursor 2
Synthesis, structure
Insights into an NEk2 inhibitory profile of nitidine chloride by molecular docking and biological evaluation PMID 36210464
From PROTAC to inhibitor Structure
Discovery of substituted 4
HI 236
Electrophysiological study with oxonol VI of passive NO3
α
Design, synthesis and biological evaluation of 2
Avenaciolide a specific inhibitor of glutamate transport in rat liver mitochondria PMID 5435480
New steroidal saponins from the bulbs of Lilium brownii var. viridulum PMID 22960210
Structural biology of the cell adhesion protein CD2 alternatively folded states and structure
1,5
Mapping inhibitor binding modes on an active cysteine protease via nuclear magnetic resonance spectroscopy PMID 23181936
Improved Methods for Assessing Therapeutic Potential of Antifungal Agents against Dermatophytes and Their Application in the Development of NP213, a Novel Onychomycosis Therapy Candidate PMID 30858219
Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor
Inhibition of the insulin
Anti
Discriminative stimulus properties of CL218872 and chlordiazepoxide in the rat PMID 2576141
Activation of a GST
Anthracycline chemicals with anthracyclinone structure exert antitumor effects by inhibiting angiogenesis and lymphangiogenesis in a xenografted gastric tumor model PMID 37344705
ZBTB9 蛋白, Human (His)
Design, synthesis and biological evaluation of 4
Enterolactone A novel radiosensitizer for human breast cancer cell lines through impaired DNA repair and increased apoptosis PMID 27984132
Neobavaisoflavone inhibits antitumor immunosuppression via myeloid
Bis
natural phytochemica
Effects of 3
Disalicylic acid
L
盐酸阿托西汀 d<sub>5</sub> (盐酸盐)
Phomopsis obscurans
A1AT modulator 2 2555004
RSAD2 suppresses viral replication by interacting with the Senecavirus A 2 C protein PMID 39334325
Polycaprolactone diol (MW 2000)
oral， CB1
CCT129397
RXR antagonist 1
Semaphorin
The enzymatic interconversion between midecamycin A1 and A3 PMID 541276
Development of Polymeric Micelles of Oleanolic Acid and Evaluation of Their Clinical Efficacy PMID 32572634
Quinaldine red 117
Cap
Hepatoprotective effect of ganoderma triterpenoids against oxidative damage induced by tert
Isobutyl
Biotin
BChE
GS 4331
Verrucarin A 3148
A novel arginine methyltransferase inhibitor with cellular activity PMID 17570663
N
Caroverine
Kuwanon B (桑皮酮B)
Genotoxic stress and viral infection induce transient expression of APOBEC3A and pro
New acetamide
Sulfadiazine 100 µg/mL in methanol
Protective effects of curcumin against amiodarone
Inhibitors of farnesyl and geranylgeranyl methyltransferases prevent beta 2 integrin
3
glycerol
RO4956371
(S)
A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy PMID 25326666
Ethyl chrysanthemate
IGFBP
Dietary Dihydromethysticin Increases Glucuronidation of 4
Unpaired guanine residues
Comparison of Tumor Non
Bovine Factor IXa Beta
Use of Freund's Complete Adjuvant (FCA) in inflammatory pain models consequences on the metabolism and pharmacokinetics of the non
Dehydroepiandrosterone/DHEA 抗体（Dehydroepiandrosterone/DHEA Antibody）
Diethyl 5,5'
cephalosporin ester
Hederacoside D
KBP
A novel pan
TRPV1 antagonist 7
HCA 2969
Interaction of Lotus
Quinonoid dihydropteridine reductase
GSI
Chromolaenide
N4
GNE
Wofapyrin 8066
Conformational changes of human beta 1 thyroid hormone receptor induced by binding of 3,3',5
Nicotine interacts with DNA lesions induced by alpha radiation which may contribute to erroneous repair in human lung epithelial cells PMID 39244876
ANGPTL8/Angiopoietin
Citiolone 1195
VPAC2 Receptor Signaling Promotes Growth and Immunosuppression in Pancreatic Cancer PMID 38809694
The synthesis of 1,2,3
Animal
Stearyl behenate 24271
Dysfunctional Decidual CD4+T Cells Induce Recurrent Pregnancy Loss via Palmitoylation
Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans PMID 30793315
The MFGE8/integrin β3 axis mitigates experimental neutrophilic asthma by suppressing NLRP3
VP
Tyrphostin B50
Microbiological Characterization of VNRX
Direct targeting of S100A9 with Icariin counteracted acetaminophen‑induced hepatotoxicity PMID 38810310
盐皮质激素受体
AF 568 NHS ester
uric acid
CD84/SLAMF5 蛋白, Rhesus Macaque (HEK293, His)
cancer stem cell
Identification of Plasmodium falciparum spermidine synthase active site binders through structure
Wnt/β
Hedycoronen A
Cap
UK
Antiproliferative agent
deaminase
DJ
西苯唑啉琥珀酸盐
PSMA inhibitor precursor
Novel alkylphospholipid
IONIS 1063734
human hepatocellular carcinoma
Synthesis and structure
Siponimod hemifumarate 1234627
HSD17B13
Naloxegol a review of its use in patients with opioid
sulfur
AZD4547 targets the FGFR/Akt/SOX2 axis to overcome paclitaxel resistance in head and neck cancer PMID 34837170
Phomalactone from a Phytopathogenic Fungus Infecting ZINNIA elegans (ASTERACEAE) Leaves PMID 26133676
B7
Developing new targeting strategy for androgen receptor variants in castration resistant prostate cancer PMID 28722220
Antibacterial agent 27
VUFB 15754
Effect of premedications in a murine model of asparaginase hypersensitivity PMID 25573198
tribbles pseudokinase 1 (TRIB1)
Inhibition of Ribonucleotide Reductase Subunit M2 Enhances the Radiosensitivity of Metastatic Pancreatic Neuroendocrine Tumor PMID 38801884
Nmd3
Design and synthesis of novel nitrogen mustard
14
antibody
Dicamba 1
Novel aminopeptidase N (APN/CD13) inhibitors derived from chloramphenicol amine PMID 21802307
Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum PMID 10530954
Sarasinoside B1 114066
Early Treatment for Covid
PRO
Small
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