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Zaragozic acid C (L
Bis(4
PROTAC 靶向蛋白降解
Molarity Calculator
STAT5抑制剂、激活剂、降解剂、基因
Angiotensin Receptor
HuR
MAPKAPK2 (MK2)
Ras
HSP
RET
Rituximab (Anti
Sirtuin
Fc
PD
Pregnane X Receptor (PXR)
Amyloid
细胞分析
MLKL
SF
ROCK
PI3K
COMT
PI3K抑制剂、 Control、 Ligand、激动剂、激活剂、调节剂、诱导剂、降解剂、基因
FITC
Siglec
氧感应化合物库
Siglec
JNK Inhibitors
支原体检测
C
Nuclear factor
p120γ抑制剂、基因
CXCR
生物活性化合物库
PI3Kβ抑制剂、降解剂、基因
NOS
COX Inhibitors
中药特征成分标准品 (Characteristic components in TCM Standards)
Mefruside
neuroprotective effects
Polo
Tetracycline抑制剂、基因
Ack1
Histone Methyltransferase
甘露聚糖结合凝集素关联丝氨酸蛋白酶 2 (MASP
lysosome
神经保护化合物库
FAAH
Endonuclease
TL4
Methionine Adenosyltransferase (MAT)
Fc
endotoxin
EAAT
登录
Inotuzumab ozogamicin (CMC
Adenylate Cyclase
激酶抑制剂库
其他类化合物 (Others)
甘露聚糖结合凝集素关联丝氨酸蛋白酶 1 (MASP
线粒体靶向化合物库
HDAC
VD/VDR
P
FKBP
Ocrelizumab (2H7，奥美珠单抗)
Gut microbiota dysbiosis orchestrates vitiligo
Amino Acid Derivatives
AZD6738 Attenuates LPS
Inhibitory effect of norharmane on Serratia marcescens NJ01 quorum sensing
Potential mechanisms of aortic medial degeneration promoted by co
Tectorigenin alleviates irinotecan
The injectable hydrogel loading cannabidiol to regulate macrophage polarization in vitro for the treatment of chronic enteritis PMID 39385453
Functional Characterization of Ao4g24 An Uncharacterized Gene Involved in Conidiation, Trap Formation, Stress Response, and Secondary Metabolism in Arthrobotrys oligospora PMID 39203374
HA1/Hemagglutinin 蛋白, H5N1 (ACO07033, HEK293, His)
Disruption of the Na+/K+
MHC
HA1/Hemagglutinin 蛋白, H5N1 (ACI06185, HEK293, His)
HA1/Hemagglutinin 蛋白, H5N1 (ACT15357, HEK293, His)
Squaramides as Bioisosteres in Contemporary Drug Design PMID 32930577
The neurotrophic activities of brain
肿瘤诱导化合物库
CCR1 enhances SUMOylation of DGCR8 by up
Europium
Apigenin suppresses influenza A virus
S100A9 inhibition ameliorates HFpEF by modulating mitochondrial fission and oxidative stress PMID 40714466
Bioengineered hybrid dual
HA1/Hemagglutinin 蛋白, H3N8 (ACE81938, sf9, His)
DNA聚合酶
Human monoamine oxidase enzyme inhibition by coffee and beta
ACAA2 Protects Against Cardiac Dysfunction and Lipid Peroxidation in Renal Insufficiency with the Treatment of S
吲哚类化合物 (Indole Alkaloids)
Enhancing MyD88 oligomerization is one important mechanism by which IBDV VP2 induces inflammatory response PMID 40067802
Anti
NA/Neuraminidase 蛋白, Influenza B (AAA43749, HEK293, His)
Neuroblast Differentiation
Polymeric Immunoglobulin Receptor
Carbohydrates
Methylprednisolone 83
VX
蛋白样本制备
Analytical approaches for the detection of emerging therapeutics and non
β
PUM1 enhances PAK6 mRNA stability and contributes to growth and ferroptosis resistance in lung adenocarcinoma cells PMID 40694989
Short
Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals PMID 30136594
Aladorian 865433
Stress granules attenuate protein nanoparticle induced osmotic imbalance via membrane potential restoration PMID 40750804
Bacterial
Topoisomerase
GDF11 promotes osteogenic/odontogenic differentiation of dental pulp stem cells to accelerate dentin restoration via modulating SIRT3/FOXO3
HA/Hemagglutinin 蛋白, H1N1 (ACP41935, sf9, His)
Azosemide is more potent than bumetanide and various other loop diuretics to inhibit the sodium
Minocycline inhibits growth of epithelial ovarian cancer PMID 22252097
NDUFA4 promotes the progression of head and neck paraganglioma by inhibiting ferroptosis PMID 37602474
Anti
Targeted Macrophage CRISPR
Screening of the active fractions from the Coreopsis tinctoria Nutt. Flower on diabetic endothelial protection and determination of the underlying mechanism PMID 32045684
中药单体化合物库
蛋白酶抑制剂 Cocktail( Protease Inhibitor Cocktail )
抗感染化合物
50K 类药多样库
CD22 ligand
B 细胞 CD 蛋白 (B Cell CD Proteins)
类器官研究
Encorafenib (LGX818)
CD38
丙型肝炎病毒蛋白 (Hepatitis C Virus Proteins)
巨噬细胞 CD 蛋白 (Macrophage CD Proteins)
Carbon monoxide ameliorates LPS
抗生素化合物库
Carbonic Anhydrase
受体蛋白 (Receptor Proteins)
耗材
MCE 乘风开学季
Nucleoprotein/NP 蛋白, Influenza A virus H1N1 (His
ABCB1
Acetylcholine chloride (ACh chloride，氯化乙酰胆碱)
Calcium Channel
HBV
SMURF1 Regulates Periodontal Stem Cell Injury and Osteogenic Differentiation by Regulating TRAF4 PMID 40259637
Belimumab (LymphoStat B，贝利尤单抗)
autophagy
2
人类免疫缺陷病毒 (HIV Proteins)
连接酶 (Ligases (EC 6))
SARS
一站式药物筛选平台
Chlorsulfuron (氯磺隆)
Carbonic
Nitric oxide synthases
Chlorsulfuron (Standard) (氯磺隆 (Standard))
高选择性抑制剂库
NOD
BTN3A3
All Products
Raf降解剂、基因
食物来源，可透过中枢神经系统，口服活性化合物库
Oligomycin B (寡霉素 B)
Triggering receptors expressed on myeloid cells
Manidipine
其他 (Others)
小激活RNA (saRNAs)
表面活性剂 (Surfactants)
亚磷酰胺单体 (Nucleoside Phosphoramidites)
platinum(II)
ribosome function
PROTAC
reperfusion injury
mAChR2抑制剂、激动剂、拮抗剂、调节剂、基因
Thrombin
antineoplastic
蛋白酪氨酸激酶化合物库
帽类似物 (Cap Analogs)
FosB抑制剂、基因
TNF Receptor Inhibitors
反义寡核苷酸 (Antisense Oligonucleotides)
pH 调节剂 (pH Modifiers)
ischemia
PKC Inhibitors
Tau
_2
E3 Ligase Ligand
Conivaptan hydrochloride (YM 087，盐酸考尼伐坦)
崩解剂 (Disintegrants)
黏合剂 (Binders)
Cholinesterase (ChE) Inhibitors
mAChR3抑制剂、激动剂、拮抗剂、调节剂、基因
ROS Kinase
螯合剂 (Chelating Agents)
isolate
微小RNA (MicroRNAs)
CDK Inhibitors
reactive oxygen species
Sodium carboxymethyl cellulose (Viscosity 800
PRN 1008
4
CLK抑制剂、基因
Indapamide
TNFRSF12A/TWEAK抑制剂、激活剂、基因
substrate
CAL
arthropod
巨噬细胞相关化合物库
Chloride
OR 1259
collagen
M 2951
Monocarboxylate Transporter
Synthesis and biological activity of 6
IL4I1 enhances PD
干细胞培养细胞因子
Advancing Predictions of Oral Drug Absorption, CYP3A4 Induction, and Transporter
Berberine Protects Against Dihydrotestosterone
Acalabrutinib (ACP
Repurposing old drugs as antiviral agents for coronaviruses PMID 32563698
Mitochondrial, metabolic and bioenergetic adaptations drive plasticity of colorectal cancer cells and shape their chemosensitivity PMID 40185729
iNOS 抗体 (YA5772)（iNOS Antibody (YA5772)）
CCG
PDE5 inhibitors An original access to novel potent arylated analogues of tadalafil PMID 17107795
Apolipoprotein E/APOE3 蛋白, Human (HEK293, His)
Glycoprotein 130 (gp130)
Hydrolysis of 2D Nanosheets Reverses Rheumatoid Arthritis Through Anti
A Mitochondrial Nanoguard Modulates Redox Homeostasis and Bioenergy Metabolism in Diabetic Peripheral Neuropathy PMID 37782570
药物浓度检测 (Therapeutic Drug Monitoring TDM)
Sundaicumones A and B, polyprenylated acylphloroglucinol derivatives from Calophyllumsundaicum with weak activity against the glucocorticoid receptor PMID 16643060
Akt
Integrative residue
Lignans with anti
Stimulation of TRPV1+ peripheral somatosensory nerves suppress inflammation via the somato
Methotrexate loaded extracellular vesicles attenuate periodontitis by suppressing ACSL1 and promoting anti
Macrophage
Bisphenol S promotes clear cell renal cell carcinoma progression by modulating the WNT5A
PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only Role of hepatic cholesterol PMID 35985474
Isolation, structural elucidation, and insights into the anti
Mori fructus
Oral direct thrombin inhibitor AZD0837 for the prevention of stroke and systemic embolism in patients with non
Inhibitory Effects of Alkaloids on OATP1B1 In Vitro and In Vivo Prediction for Food/Herb
Cholesterol
Cationic lipid
Quercetin inhibits herpes simplex virus 1 replication in corneal epithelium and suppresses keratitis progression PMID 40675379
Exploring the mechanism of α
Comparison of the effects of nifedipine and nisoldipine on coronary vasoconstriction in the Langendorff
Multi
VO
Gut microbiota derived butyrate enhances ferroptosis sensitivity in endometriosis through FFAR2/PPAR
Clusterin mediates hydroquinone
抗体偶联药物毒素分子库
Cinobufotalin 1108
ORIC
Immunosuppressive Nor
Asprosin
Structural design, synthesis and substituent effect of hydrazone
Tadalafil for the treatment of pulmonary arterial hypertension PMID 22356534
Mechanistic differences in eukaryotic initiation factor requirements for eIF4GI
Dimethyl sulfoxide (DMSO) as intravesical therapy for interstitial cystitis/bladder pain syndrome A review PMID 28220525
Design, synthesis and biological activity of N5
Iguratimod, a promising therapeutic agent for COVID
Berberine Inhibits Acne
The role of RUNX1/NF
Central nervous system blockade by peripheral administration of AT1 receptor blockers PMID 12658061
Tetramisole 5036
Structure
Radiosynthesis of a Bruton's tyrosine kinase inhibitor, [11 C]Tolebrutinib, via palladium
Molecular mechanism of a triazole
Lactic Acid
Doxorubicin synergizes bortezomib
CRISPRa
ACSS2 drives senescence
N,N
Structure
Cinnamaldehyde alleviates pulmonary hypertension by affecting vascular remodeling through the TLR4/NF
Injectable drug depot engineered to release multiple ophthalmic therapeutic agents with precise time profiles for postoperative treatment following ocular surgery PMID 29684622
Tumor Targeting with Novel Pyridyl 6
Developmental expression of carbonic anhydrase
Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines PMID 19133137
The gut microbiota regulates autism
Devazepide 103420
Piezo1 regulates colon stem cells to maintain epithelial homeostasis through SCD1
Nitazoxanide inhibits acetylated KLF5
Imatinib and methazolamide ameliorate COVID
cardiovascular hormone
Unveiling the Mechanism of Compound Ku
Restraining the flexibility of the central linker in terameprocol results in constrained analogs with improved growth inhibitory activity PMID 24080463
Characterization of a deazaflavin analog as a potent inhibitor of multidrug resistance
Nanosilver
Discovery of DS
Biotin
GSK
The effect of vitamin B6 on dexamethasone
Reduced Malignancy of Super Methotrexate
Small molecule targeting topoisomerase 3β for cancer therapy PMID 34740818
In
Bisbenzylisoquinoline alkaloids inhibit influenza virus replication by disrupting endosomal acidification PMID 40468427
Chronic PDE
Targeting the cholesterol
Nisoldipine Inhibits Influenza A Virus Infection by Interfering with Virus Internalization Process PMID 36560742
AF6 regulates intestinal IgA via crosstalk between intestinal epithelial cells and immune cells in inflammatory bowel disease PMID 40687779
Design, synthesis and biological activities of tetrandrine and fangchinoline derivatives as antitumer agents PMID 28057423
Disulfiram Alleviates MTX
Role of Aspirin and Dexamethasone against Experimentally Induced Depression in Rats PMID 26645736
Carrier
Crebanine mitigates glucocorticoid
Kaempferide 491
Atorvastatin
Plasma Membrane
An Integrated Strategy for the Detection, Dereplication, and Identification of DNA
Scutellarin inhibition of the rosuvastatin uptake in rat hepatocytes and the competition for organic anion transporting polypeptide 1B1 in HEK293T cells PMID 31992796
Psoralidin inhibits osteosarcoma growth and metastasis by downregulating ITGB1 expression via the FAK and PI3K/Akt signaling pathways PMID 37004120
Activation of Rev
Triangulating variation in the population to define mechanisms for precision management of genetic disease PMID 35714602
Indapamide lowers blood pressure by increasing production of epoxyeicosatrienoic acids in the kidney PMID 23729436
Hit
Phenanthriplatin 1416900
Nuclear receptor Rev
A clinically compatible drug
Shuangdan Jiedu Decoction improved LPS
Generation of Highly Selective, Potent, and Covalent G Protein
House dust mite induced mucosal barrier dysfunction and type 2 inflammatory responses via the MAPK/AP
Fluorinated Ribonucleocarbohydrate Nanoparticles Allow Ultraefficient mRNA Delivery and Protein Expression in Tumor
Atorvastatin inhibits inflammatory hypernociception PMID 16865092
Cholesterol depletion sensitizes gallbladder cancer to cisplatin by impairing DNA damage response PMID 31599189
Synthesis and evaluation of pyrazolo[3,4
From Centralized to Ad
Effects of finasteride on size of the prostate gland and semen quality in dogs with benign prostatic hypertrophy PMID 11330612
Afoxolaner (Standard)
Ultrasmall Bi@Au Schottky Heterojunction with a High Potential Barrier for Amplifying Radioimmunotherapy PMID 40113590
Enalaprilat 76420
Effect of long
Efficacy of Lenvatinib, a multitargeted tyrosine kinase inhibitor, on laser
Substituted 4
Gut microbiota of miR
Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway PMID 35749236
Structural basis of human monocarboxylate transporter 1 inhibition by anti
Effects of balanced vasodilator, flosequinan, on aortic impedance in failing heart PMID 9733361
β
OTULIN confers cisplatin resistance in osteosarcoma by mediating GPX4 protein homeostasis to evade the mitochondrial apoptotic pathway PMID 39721999
CKN reduces TLR4
Diarylheptanoids with NO production inhibitory activity from Amomum kravanh PMID 32070636
Ibrutinib Displays Atrial
AR
Triiodothyronine (T3) promotes browning of white adipose through inhibition of the PI3K/AKT signalling pathway PMID 39223267
Recent advancements in the development of heterocyclic anti
Superior Pyrimidine Derivatives as Selective ABCG2 Inhibitors and Broad
Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS
Berberine chloride hydrate impairs Streptococcus mutans biofilm formation via inhibiting sortase A activity PMID 40595693
The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144 PMID 19863083
Antinociception induced by amitriptyline and imipramine is mediated by alpha2A
Comprehensive study on potent and selective carbonic anhydrase inhibitors Synthesis, bioactivities and molecular modelling studies of 4
Synthesis and biological evaluation of 2
Glycolysis and Reactive Oxygen Species Production Participate in T
Inhibitors of dihydrofolate reductase as antitumor agents design, synthesis and biological evaluation of a series of novel nonclassical 6
Effects of manidipine hydrochloride on the renal microcirculation in spontaneously hypertensive rats PMID 1282591
The Effects and Mechanism of ATM Kinase Inhibitors in Toxoplasma gondii PMID 39000057
Sulodexide inhibits retinal neovascularization in a mouse model of oxygen
MiR
Histone Deacetylase Inhibitor (SAHA) Reduces Mortality in an Endotoxemia Mouse Model by Suppressing Glycolysis PMID 37569823
Disrupting pro
Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8 PMID 38040762
TRPM2
Kaempferide (Standard)
ErbB3/HER3抑制剂、拮抗剂、降解剂、基因
Further observations on flumethiazide. A new oral diuretic agent PMID 13801925
Network pharmacological mechanism of Cinobufotalin against glioma PMID 34560920
A novel mouse model of familial combined hyperlipidemia and atherosclerosis PMID 38459255
抗阿尔茨海默病化合物库
A32390A 61241
Finasteride acetate 222989
Tolebrutinib 1971920
Trimethaphan bromide 21035
Reactive oxygen species
Exposure to diisononyl phthalate induced an increase in blood pressure through activation of the ACE/ AT1R axis and inhibition of NO production PMID 30940551
Isosaxalin 55481
Fostemsavir sodium 864953
Solidagolactone II 24399
靶向治疗药物库
Manidipine 89226
Ligustilide covalently binds to Cys129 of HMGCS1 to ameliorate dyslipidemia PMID 37579692
Ethonafide 160554
Essential oil extracted from Quzhou Aurantii Fructus prevents acute liver failure through inhibiting lipopolysaccharide
Higenamine 5843
Pirtobrutinib (LOXO
Acalabrutinib 1420477
助溶剂 (Co
(±)
dopamine β
Iproplatin 62928
Pharmacotranscriptomic profiling of resistant triple
Acebutolol 37517
布鲁顿酪氨酸激酶 (Brutons Tyrosine Kinase (BTK))
Tetramisole is a new IK1 channel agonist and exerts IK1
vitamin K
高血压模型 (Hypertension Models)
Gestational cadmium exposure impairs placental angiogenesis via activating GC/GR signaling PMID 34411824
β1 adrenergic receptor
Evobrutinib 1415823
In vitro and in vivo anti
Asnuciclib 1421693
Clevidipine 167221
Comparison of the efficacies of five different statins on inhibition of human saphenous vein smooth muscle cell proliferation and invasion PMID 18049315
Icariin attenuates oxidative stress via SIRT1/PGC
Tumor
Atecegatran metoxil
Roxatidine 78273
Locostatin (UIC
Non
expansion of blood vessels
Scutellarin Alleviates Ovalbumin
Rutin promotes white adipose tissue browning and brown adipose tissue activation partially through the calmodulin
Identification of novel CDK 9 inhibitors based on virtual screening, molecular dynamics simulation, and biological evaluation PMID 32781071
α2 adrenoceptors
Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα PMID 22766217
Nebivolol hydrochloride 152520
Lactate limits CNS autoimmunity by stabilizing HIF
Effect of flutonidine on ouabain
PPI抑制剂库
Autophagy activation ameliorates the fibrosis of trabecular meshwork cells induced by TGFβ2 through the promotion of fibrotic proteins degradation PMID 39436499
Breast cancer insights in disease and influence of drug methotrexate PMID 33479665
4
Superior oblique myokymia
Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity PMID 19549602
Iminolactones from Schizophyllum commune PMID 25951057
GnRH
Berberine promotes primordial follicle activation and increases ovulated oocyte quantity in aged mice PMID 39707173
Dancing of the second aromatic residue around the 6,8
Pan
A novel L
AZD3965 1448671
Mutant KRAS
Discovery of novel 3
Double Methotrexate
A stop
anti
蛋白酶抑制剂化合物库
scRNA
Single
Novel BTK inhibitor acalabrutinib (ACP
Atorvastatin induces autophagy in MDA
AChE/hCA I
Hippocampal mitophagy contributes to spatial memory via maintaining neurogenesis during the development of mice PMID 38887162
Gut microbiota
EHNA hydrochloride 58337
Bimatoprost (Standard)
Discovery of the Potent and Highly Selective PARP7 Inhibitor as a Novel Immunotherapeutic Agent for Tumors PMID 36576395
γ
Piboserod 152811
Clopamide 636
Revisit ligand
Lead (II) iodide 10101
immune diseases
Bamethan hemisulfate 5716
Metformin Promotes Beclin1
Synthesis and structure
Withaferin A induces cell death and differentiation in multiple myeloma cancer stem cells PMID 30108696
Cardiac structural remodelling after treatment of spontaneously hypertensive rats with nifedipine or nisoldipine PMID 8252599
Mulberroside A mitigates intervertebral disc degeneration by inhibiting MAPK and modulating Ppar
Identification of FBLL1 as a neuron
Conivaptan 210101
α1 adrenoceptors
Myelin Basic Protein 126768
Hemodynamics of dexamethasone
Balantidium coli.
Jiao
CDK9 inhibitor CDKI
碳酸酐酶 11（CA11）基因
Farnesyl Transferase
抗癌上市药物库
蓝色琼脂糖凝胶 6FF (Blue Agarose 6FF)
ApoE 抗体 (YA1516)（ApoE Antibody (YA1516)）
磷酸酶抑制剂 Cocktail I (Phosphatase Inhibitor Cocktail I)
10
蛋白酶抑制剂 Cocktail (Protease Inhibitor Cocktail)
Vasoconstriction Inhibition
NSC 77037
outflow facility
Guanylate Cyclase
hypotensive
SF3B1抑制剂、基因
Blood Pressure Lowering
Pladienolide B
neutrophils
CDK7抑制剂、降解剂、基因
Novel 6
Structurally Diverse Labdane Diterpenoids from Leonurus japonicus and Their Anti
曲安西龙
Effect of 0.04% AR
Dexamethasone
Berberine
ErbB4/HER4抑制剂、基因
Nisoldipine
定制合成服务
high lipophilic character
SH
BAY 10
Donafenib activates the p53 signaling pathway in hepatocellular carcinoma, induces ferroptosis, and enhances cell apoptosis PMID 39753901
Acalabrutinib
Serotonin Transporter
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