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Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single
Mechanistic insights into 5
Transactivation domain of Krüppel
Nucleolar Localization of the RNA Helicase DDX21 Predicts Survival Outcomes in Gynecological Cancers PMID 38767454
Lipid Droplets Are Beneficial for Rabies Virus Replication by Facilitating Viral Budding PMID 34757839
Two phenylpropanoid glycosides from Leonurus glaucescens PMID 1367886
D
Esamisulpride 71675
CD63
Sacubitril/Valsartan partially alleviates myocardial infarction injury by activating the FGF21 signaling pathway via PPARs PMID 39987117
E3 ubiquitin ligase TRIM21 targets TIF1γ to regulate β
Genipin 6902
Modeling drug
Hypoxia
3
Fallaxsaponin A 1287702
Amoxicillin 26787
Keratinocyte growth factor
含氧花生酸受体 1（OXER1）基因
H
Photo
The anti
Monitoring of polycyclic aromatic hydrocarbons and probabilistic health risk assessment in yogurt and butter in Iran PMID 33841828
Erysipelas a common potentially dangerous infection PMID 17994173
Zymostenol 566
Serum miR
TNP
Thieno[2,3
Glutathione transferase Omega 1
Ibuprofen
Strontium ranelate a dual mode of action rebalancing bone turnover in favour of bone formation PMID 16735840
Asparagusic acid 2224
ABCG2 is an itaconate exporter that limits antibacterial innate immunity by alleviating TFEB
The anti
Single
DL
Antinociceptive properties of neurosteroids II. Experiments with Saffan and its components alphaxalone and alphadolone to reveal separation of anaesthetic and antinociceptive effects and the involvement of spinal cord GABA(A) receptors PMID 11098097
Metabolic determinants of germinal center B cell formation and responses PMID 39060389
SynB1 1207092
ROR2 蛋白, Human (Biotinylated, HEK293, His
Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer PMID 28871105
Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis PMID 22040680
Homeostasis of branched
Indinavir sulfate 157810
mal，T 细胞分化蛋白样（MALL）基因
Propargyl
Repurposing AZD5438 and Dabrafenib for Cisplatin
Viloxazine 46817
Treatment with melagatran alone or in combination with thrombolytic therapy reduced ischemic brain injury PMID 18598697
Structure of neprilysin in complex with the active metabolite of sacubitril PMID 27302413
The dipeptide Arg
FER
CD150/SLAMF1 蛋白, Human (Biotinylated, HEK293, His
Nucleoside Inhibitors of Zika Virus PMID 27234417
Inhibition of inosinic acid dehydrogenase by 8
Resinacein L 2259327
GUCY2C Human Pre
CDK1 mediates the metabolic regulation of DNA double
hsa
Anti
Fenchyl alcohol 1632
Anti
Effects of piclozotan (SUN N4057), a partial serotonin 1A receptor agonist, on motor complications induced by repeated administration of levodopa in parkinsonian rats PMID 20858480
Synergistic PIM kinase and proteasome inhibition as a therapeutic strategy for MYC
Design, synthesis, and pharmacological characterization of N
白细胞介素 17C（IL17C）基因
RET
Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice PMID 29920354
Doublecortin 抗体 (YA3541)（Doublecortin Antibody (YA3541)）
Boc
Synthesis and evaluation of 17α
Squalamine lactate 320725
Withanolides derived from Physalis peruviana (Poha) with potential anti
ZAKα Induces Pyroptosis of Colonic Epithelium Via the Caspase
HCoV229E
Photoregulin1
Remodeling of metabolism and inflammation by exercise ameliorates tumor
Downregulation of RUNX1
Bilberry extract (Antho 50) selectively induces redox
T
α
Nuclear ubiquitination permits Hippo
Corchoionoside C 185414
Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria PMID 30032754
A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias PMID 23010360
Famciclovir 104227
IL
Identification of another actin
Overlapping functions between Lamp2a and Lamp2b in cardiac autophagy PMID 40202173
Integrative analysis of genes provides insights into the molecular and immune characteristics of mitochondria
PD
TNF
The basis for IL
Demethoxyencecalinol 71822
In vitro and in vivo evaluation of select kahalalide F analogs with antitumor and antifungal activities PMID 21839640
(S)
Selenium
Mitochondria
损伤相关分子模式
A simple automated solid
ASP1126 1228580
Gomisin J attenuates cerebral ischemia/reperfusion injury by inducing anti
Neuroprotective Effect of the LRRK2 Kinase Inhibitor PF
Restricting Glutamine Uptake Enhances NSCLC Sensitivity to Third
C646 degrades Exportin
Nanokit coupled electrospray ionization mass spectrometry for analysis of angiotensin converting enzyme 2 activity in single living cell PMID 35602918
Upregulation of PDGF Mediates Robust Liver Regeneration after Nanosecond Pulsed Electric Field Ablation by Promoting the HGF/c
Macrocyclic Azapeptide Nitriles Structure
Simultaneous determination of elbasvir and grazoprevir in fixed
NVP
AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF
Chalcone tetramers, lophirachalcone and alatachalcone, from Lophira alata as possible anti
Anti
Optimization of diarylazines as anti
Self
PKR activator 1 2283420
4'
Fraxin inhibits ovariectomized
Microbial transformation of trichostatin A to 2,3
Assessment of Metacaspase Activity in Phytoplankton PMID 33654845
Inhibition of protein, RNA and DNA synthesis in Escherichia coli by p
Extended structure
n
Salmonella Typhimurium persistently infects host via its effector SseJ
H2ax
Lanabecestat camsylate 1522418
Ertapenem (MK
Y
Geniposide inhibits SphK1 membrane targeting to restore macrophage polarization balance in collagen
Transport of the areca nut alkaloid arecaidine by the human proton
Dynamic heterogeneity towards drug resistance in AML cells is primarily driven by epigenomic mechanism unveiled by multi
DMT
Non
In Vitro Cytotoxic Effects of Celecoxib, Mefenamic Acid, Aspirin and Indometacin on Several Cells Lines PMID 27602398
USP22 promotes the proliferation and Sorafenib resistance of hepatocellular carcinoma cells via its deubiquitinase activity PMID 40341781
IFN
Fenoverine inhibition of calcium channel currents in single smooth muscle cells from rat portal vein and myometrium PMID 1786520
Taraxasterol from Taraxacum prevents concanavalin A
Phosphatidylserine
Antineoplastic agents. 534. isolation and structure of sansevistatins 1 and 2 from the African Sansevieria ehrenbergii PMID 15921418
Inhibition of bromodomain and extra
Mitophagy
Role of the Glycogen Synthase Kinase 3
Ranbezolid (RBx7644 free base)
Nocathiacin II 256230
ATG7
Cd70
Genomic insights and phenotypic characterization of three multidrug resistant Cupriavidus strains from the cystic fibrosis lung PMID 40246707
Amisulpride 71675
Promecarb
Asymptomatic Hyperuricemia Is Associated with Achilles Tendon Rupture through Disrupting the Normal Functions of Tendon Stem/Progenitor Cells PMID 36504525
FFP
Therapeutically reprogrammed nutrient signalling enhances nanoparticulate albumin bound drug uptake and efficacy in KRAS
10,11
Gingerenone A 128700
HPV18
Lavendustin C 125697
In vivo and in vitro studies of antisense oligonucleotides
Integrated Computational and Functional Screening Identify G9a Inhibitors for SETD2
缺氧诱导因子 1 亚基 α（HIF1A）基因
β
LY2510924
Amino acid derivatives as bitter taste receptor (T2R) blockers PMID 25059668
Erythromycin Estolate Inhibits Zika Virus Infection by Blocking Viral Entry as a Viral Inactivator PMID 31731598
Host CARD11 Inhibits Newcastle Disease Virus Replication by Suppressing Viral Polymerase Activity in Neurons PMID 31554683
LncRNA HEPFAL accelerates ferroptosis in hepatocellular carcinoma by regulating SLC7A11 ubiquitination PMID 36008384
LW106
Copper(II) diethyldithiocarbamate (Diethyldithiocarbamic acid copper salt)
FAP
Structure Optimization of Aloperine Derivatives as HIV
Deoxyribose analogues of N6
FR
UNC4976 TFA
Biological evaluation of tetracationic compounds based on two 1,4
Tomatidine Ameliorates Diabetes
HPA aptamer functionalized paclitaxel
Triethylmethylammonium chloride 10052
Gypenosides counteract hepatic steatosis and intestinal barrier injury in rats with metabolic associated fatty liver disease by modulating the adenosine monophosphate activated protein kinase and Toll
Decreased glycation and structural protection properties of γ
Structure
Androgen is responsible for enhanced susceptibility of melatonin against traumatic brain injury in females PMID 33766734
Dinotefuran 165252
氨基酰化酶 3（ACY3）基因
ZXX2
3
Epithelial sphingolipid sorting allows for extensive variation of the fatty acyl chain and the sphingosine backbone PMID 1590779
B vitamins induce an antinociceptive effect in the acetic acid and formaldehyde models of nociception in mice PMID 11516431
SIRT1 activation attenuates cardiac fibrosis by endothelial
Allosteric activation of the metabolic enzyme GPD1 inhibits bladder cancer growth via the lysoPC
Aprutumab 1634620
Inhibition of P2X7R by hypericin improves diabetic cardiac autonomic neuropathy through the proteasome
Diclofenac
Doxycycline inhibits the cancer stem cell phenotype and epithelial
Bacopaside X 94443
Nanopore RNA direct sequencing identifies that m6A modification is essential for sorbitol
Tofacitinib prevents depressive
Psoralen Derivatives as Inhibitors of Mycobacterium tuberculosis Proteasome PMID 32178473
Bradykinin (1
Norcantharidin promotes M1 macrophage polarization and suppresses colorectal cancer growth PMID 40394236
IOX5
Bromochlorophenol blue 2553
Secologanate 22864
ZSTK474 475110
Inhibiting von Hippel‒Lindau protein
Quinapril 85441
Dual
Novel ATR/PARP1 Dual Inhibitors Demonstrate Synergistic Antitumor Efficacy in Triple
Elimination profile of methylthiouracil in cows after oral administration PMID 10435313
Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness PMID 31816622
Oxide
The SIRT5
Tetraniliprole
The Usnic Acid Analogue 4
Structural basis for GLP
Pioglitazone hydrochloride 112529
Inhibition of equine mononuclear cell proliferation and leukotriene B4 synthesis by a specific 5
Multifactorial interaction and influence of culture conditions on yellow fluorescent protein production in Phaeodactylum tricornutum PMID 40044057
RhoA
Ovalbumin (154
Antagonism of stimulus properties of nicotine by dihydro
1
Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury PMID 40365742
Golidocitinib 2091134
The involvement of NLRP3 inflammasome in CUMS
Idrabiotaparinux 774531
Knockdown of GBP1 inhibits BCG
GPC3 targeting peptide 1 3066113
Protective effect of hydroxysafflor yellow A on cyclosporin A
A68930 hydrochloride 130465
干扰素α4（IFNA4）基因
In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosis PMID 28204548
Re 80
MCE
HY
Identification of potential diagnostic biomarkers of atherosclerosis based on bioinformatics strategy PMID 37173673
Inhibition of miR
Methazolamide 554
Fosmidomycin 66508
Trimethylammonium chloride 593
Neoflavonoids and related constituents from Nepalese propolis and their nitric oxide production inhibitory activity PMID 15974608
Olsalazine inhibits cell proliferation and DNA methylation in canine lymphoid tumor cell lines PMID 35179837
2
Anti
Effects of Chemical Speciation on Chronic Thyroid Toxicity of Representative Perfluoroalkyl Acids PMID 40053324
Antispasmodic activity of xanthoxyline derivatives structure
白介素 3 受体亚基 α（IL3RA）基因
L
Cremophor EL
MELK
8
Tentoxin 28540
Synthesis, cytotoxic evaluation, and DNA binding of novel thiazolo[5,4
Creatine kinase in cell cycle regulation and cancer PMID 27020776
Intracellular metabolite β
CJ033466 519148
LP
Asperindoles A⁻D and a p
Rupatadine, a new potent, orally active dual antagonist of histamine and platelet
YAP
CD40L
Isovitexin
Additive Effects of Levodopa and a Neurorestorative Diet in a Mouse Model of Parkinson's Disease PMID 30127735
Brassinolide 72962
Synthesis and biological activity of sulphostin analogues, novel dipeptidyl peptidase IV inhibitors PMID 15653346
3
Activity
PRMT3 promotes tumorigenesis by methylating and stabilizing HIF1α in colorectal cancer PMID 34753906
Saralasin
Reproduction strategy of nocturnal marine molluscs running for love PMID 36609825
Inhibition of FGF Receptor
A potent and orally active antagonist (SM
ADAM 金属肽酶域 9（ADAM9）基因
Chondroitinase AC II (软骨素AC外切酶)
Anserine
Gemtuzumab ozogamicin PMID 11511025
Minimal contribution of desmethyl
Paclitaxel metabolites in human plasma and urine identification of 6 alpha
Tartaric acid disodium dihydrate
Design and synthesis of Lapatinib derivatives containing a branched side chain as HER1/HER2 targeting antitumor drug candidates PMID 25305330
Chemistry and biology of deoxynyboquinone, a potent inducer of cancer cell death PMID 20345134
ACAT1 Human Pre
Sodium tanshinone IIA sulfonate inhibits hypoxia
Dexamethasone and sodium carboxymethyl cellulose prevent postoperative intraperitoneal adhesions in rats PMID 25714889
Dehydroandrographolide 134418
Discovery of 1
Vicenin
BCMA/TNFRSF17 蛋白, Rhesus Macaque (Biotinylated, HEK293, Fc
(2,6
Unraveling the Role of METTL3 in Helicobacter pylori
diMal
AMPK activator 17
Argon Alleviates Bone Cancer Pain by Mitigating Neuronal Ferroptosis via the TLR2
Norfenfluramine hydrochloride 673
Tricaprilin
Variable cyanobacterial death modes caused by ciprofloxacin in the aquatic environment Prioritizing antibiotic
ZM 306416 (CB 676475)
Decyl methyl ether 7289
Paralogs of the Calcium
INT
Bay 65
Bioaffinity Ultrafiltration Combined with HPLC
Lepidiline A Improves the Balance of Endogenous Sex Hormones and Increases Fecundity by Targeting HSD17B1 PMID 32239630
Pharmacokinetics of florfenicol and its metabolite, florfenicol amine, in the Korean catfish (Silurus asotus) PMID 16420300
Agitoxin2
AZD2906
Unveiling a Novel Mechanism of Enhanced Secretion, Cargo Loading, and Accelerated Dynamics of Bacterial Extracellular Vesicles Following Antibiotic Exposure PMID 40704571
The X
Ogerin 1309198
Differential subcellular distribution of mitoxantrone in relation to chemosensitization in two human breast cancer cell lines PMID 17296624
Fluvirucin A1 137019
(S)
AP20187 (B/B Homodimerizer)
Glysperin C 78213
TRAIL receptors promote constitutive and inducible IL
Cytotoxicity of PEGylated liposomes co
CD117/c
Pomalidomide
Development of an advanced separation and characterization platform for mRNA and lipid nanoparticles using multi
Ifosfamide 3778
Orlistat
Fasnall, a Selective FASN Inhibitor, Shows Potent Anti
Solution
Rapid genotyping of single nucleotide polymorphisms using novel minor groove binding DNA oligonucleotides (MGB probes) PMID 11968088
Fmoc
Comparative pharmacology of human beta
Pharmacokinetic modulation of irinotecan metabolites by sulphobromophthalein in rats PMID 15231047
The 3
Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors PMID 33186520
JNJ
A new antibiotic traps lipopolysaccharide in its intermembrane transporter PMID 38172635
Antileishmanial assessment of isoxazole derivatives against L. donovani PMID 33479698
CEBPA
Vitamin D3/VDR inhibits inflammation through NF
Furanodienone induces apoptosis via regulating the PRDX1/MAPKs/p53/caspases signaling axis through NOX4
4
(20S)
Lobetyol 136171
Ccnb2 Mouse Pre
Amide
hippocampus
Metformin Promotes Proliferation of Mouse Female Germline Stem Cells by Histone Acetylation Modification of Traf2 PMID 37354386
ALK5
Pirlindole
Antiparasitic hybrids of Cinchona alkaloids and bile acids PMID 23816880
Protective effect of hepatocyte
4'
α
Proteomics
BMS
J
Eif5a
Selective inhibition of interleukin
Pyroporphyrin dimethyl ester 10589
Low
Cyclo(Phe
(R)
GelMA, 30% methacrylation 2280018
6′
Empagliflozin 864070
Mirk/Dyrk1B Kinase Inhibitors in Targeted Cancer Therapy PMID 38675189
ACVR1/ALK2
Enpp
Dasatinib N
Renal ischemia/reperfusion injury in rats is probably due to the activation of the 5
Daunorubicin and its hydroxy metabolite in cardiomyocytes insights into cellular kinetics, toxicity, DNA damage, and dexrazoxane
Structure
Comparison of fidaxomicin, thuricin CD, vancomycin and nisin highlights the narrow spectrum nature of thuricin CD PMID 38722061
AM
Immunotherapy for Alzheimer's disease targeting β
Studies on the mechanism by which cyanine dyes measure membrane potential in red blood cells and phosphatidylcholine vesicles PMID 4842277
Identification of novel benzothiopyranone compounds against Mycobacterium tuberculosis through scaffold morphing from benzothiazinones PMID 30336450
CD44 蛋白, Human (HEK293, Fc)
D
MCE
New, highly potent and non
(S,R,S)
Heterogenous Origins of Calcium Homeostasis Disorders Arising from Five Heterozygous Calcium
EGFR/HER2
Molecular glues that inhibit specific Zn2+
HS 80
细胞毒性 T 淋巴细胞相关蛋白 4（CTLA4）基因
Aminopterin N
The role of estrogen receptors (ERs)
Type
Channel catfish virus entry into host cells via clathrin
Structure
DSPE
NAT10 acetylates BCL
SPiDER
mTORC1
The GRK2/AP
Structure
Guadecitabine increases response to combined anti
MicroRNA let
Lithospermic acid alleviates oxidative stress and inflammation in DSS
Autophagosome
BODIPY
基质金属肽酶 2（Mmp2）基因
DAyne 1866495
L
Inhibitory Effects of Cytosolic Ca(2+) Concentration by Ginsenoside Ro Are Dependent on Phosphorylation of IP3RI and Dephosphorylation of ERK in Human Platelets PMID 26355658
含羞草提取物 (Mimosa pudica Linn.)
Inhibition of histone methyltransferase G9a aggravates phenotypic severity of hepatic lipotoxicity in non
Camk2n1 deficiency reduces the NaCl cotransporter activity through the CUL3/KLHL3/WNK4 complex in the kidney PMID 39798916
Field trials of an oral calcium propionate paste as an aid to prevent milk fever in periparturient dairy cows PMID 8708097
Padoprazanum fumarate 2938973
The PPAR alpha agonist gemfibrozil is an ineffective treatment for spinal cord injured mice PMID 21963672
Discovery of Clinical Candidate BMS
Dynamic investigation of hypoxia
Ald
Trop2 and its overexpression in cancers regulation and clinical/therapeutic implications PMID 26000093
ADP 核糖基化因子样 GTPase 13B（ARL13B）基因
Surzebiclimab 2342597
Meropenem 96036
Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo drug treatment with clorsulon PMID 14714178
3,4
S100A8 Promotes Inflammation via Toll
Novel management strategies for idiopathic pulmonary fibrosis PMID 30136607
In vitro antimalarial activity of limonoids from Khaya grandifoliola C.D.C. (Meliaceae) PMID 10661881
Gasdermin D restricts anti
Effects of tea polyphenols on UVA
A calicheamicin conjugate with a fully humanized anti
IGF2BP2 regulates inflammation in ulcerative colitis through N6
The small
TYK2 ligand 2 2924460
Seizures in PPT1 Knock
Animal
Lox
Protein
Protective effects of verbenalin and (+)
Purinergic Antagonist Suramin Aggravates Myocarditis and Increases Mortality by Enhancing Parasitism, Inflammation, and Reactive Tissue Damage in Trypanosoma cruzi
Extracellular Hsp90 of Candida albicans contributes to the virulence of the pathogen by activating the NF
A profiling study of a newly developed HCVcc strain PR63cc's sensitivity to direct
Synergistic effects of laminin
Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA
Pramipexole
Apigenin attenuates ischemia
Urease of Aspergillus fumigatus Is Required for Survival in Macrophages and Virulence PMID 36916906
Pomalidomide
Syk
MiR
CXC 基序趋化因子配体 8（CXCL8）基因
Carboxylesterase
Subcutaneous Administration of Angiotensin
Lead optimization of 8
Gomisin S 119239
Digoxin Ameliorates Glymphatic Transport and Cognitive Impairment in a Mouse Model of Chronic Cerebral Hypoperfusion PMID 34704235
Discovery of danoprevir (ITMN
Metal
Ethacridine lactate
Design, synthesis and biological evaluation of 6
Safety, Efficacy, and Pharmacokinetics of Almonertinib (HS
Disposition of timiperone, 4'
Protection of mitochondrial functions against oxidative stresses by isoflavans from Glycyrrhiza glabra PMID 10714953
Nuclear protein HMGN2 attenuates pyocyanin
Alfuzosin
Antitumor activity of Z
Effect of chelerythrine against endotoxic shock in mice and its modulation of inflammatory mediators in peritoneal macrophages through the modulation of mitogen
11
Pyronaridine tetraphosphate is an efficacious antiviral and anti
ZMF
Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity PMID 38649304
Synthesis and anti
Glutamate utilization fuels rapid production of mitochondrial ROS in dendritic cells and drives systemic inflammation during tularemia PMID 40880474
2′
Potent Small
DL
Gefitinib
Preparation of maltodextrin nanoparticles and encapsulation of bovine serum albumin
Matrix metalloproteinase inhibitor, CTS
Scribble mis
超氧化物歧化酶 2（SOD2）基因
Structure
PDE2 inhibitor
Moderate oxidative stress promotes epithelial
HSD17B13
Chitosan/dextran
IL
TNF 受体超家族成员 25（TNFRSF25）基因
Inhibition of melanogenesis by 3
AEA
SVS
PLAT Human Pre
Identification of New Modulators and Inhibitors of Palmitoyl
Norquetiapine 5747
BALB/3T3
PI3K/AKT confers intrinsic and acquired resistance to pirtobrutinib in chronic lymphocytic leukemia PMID 39018782
7
HPK1
Identification and characterization of human PEIG
NAMPT degrader 1
1,3
Fungichromin production by Streptomyces sp. WP
Synergistic Effects of Jerusalem Artichoke in Combination with Pegylated Interferon Alfa
DUB
RACGAP1 modulates ECT2
Technology evaluation CC49 humanized radioimmunoconjugates, National Cancer Institute PMID 14513687
Modelling fatty liver disease with mouse liver
Homeobox a5 Promotes White Adipose Tissue Browning Through Inhibition of the Tenascin C/Toll
Mechanism of bone
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