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Acronycidine
MCE
The Effect of Resveratrol in Sirt1/CST Pathway to Inhibit TNF
Tasosartan 145733
G 蛋白偶联受体 88（Gpr88）基因
ATPase
NLRX1 deficiency exacerbates skin inflammation in atopic dermatitis by disrupting mitophagy PMID 39884322
Dexamethasone phosphate 312
Effects of aminopentol on in utero development in rats PMID 16081197
LYN
S
(
(R)
HEK293T
IL
ACE2 蛋白, Rat (HEK293, His)
Discovery of the Next
FIDAS
MCE
Efficient NIR
Leucopyrokinin
Talfirastide acetate 2855063
Patamostat 114568
Linear self
disorder
Transient receptor potential channel 6 knockdown prevents apoptosis of renal tubular epithelial cells upon oxidative stress via autophagy activation PMID 30282964
Fibroblast to macrophage
5
Z
Synthesis and cytotoxic activity of new azepino[3',4' 4,5]pyrrolo[2,1
OX40 Ligand/TNFSF4 蛋白, Human (HEK293, His)
IRAK1BP1
Visualization of Positive and Negative Sense Viral RNA for Probing the Mechanism of Direct
TMPPAA 844900
Induction of DNA damage, inhibition of DNA synthesis and suppression of c
Climbazole
Cyamemazine
Armepavine 524
Structure
Adrenosterone
动力蛋白细胞质 1 轻中间链 1（DYNC1LI1）基因
MSC 2032964A
PF
differentiation
Fatty Acid Oxidation
Endoplasmic reticulum stress
TBHQ 1948
Sweroside Protects Against Myocardial Ischemia
Analysis of Phenolic Compounds of Reynoutria sachalinensis and Reynoutria japonica Growing in the Russian Far East PMID 39683123
RPE 蛋白, Human (HEK293, His)
TriDAP 877462
Top Publications Citing MCE Products
Idebenone
Identification of campesterol from Chrysanthemum coronarium L. and its antiangiogenic activities PMID 17604370
Tricaine
Modulating TRADD to restore cellular homeostasis and inhibit apoptosis PMID 32968279
CDK2
Discovery of a novel mechanism of steroid receptor antagonism WAY
Icariside I reduces breast cancer proliferation, apoptosis, invasion, and metastasis probably through inhibiting IL
SHMT2 promotes the tumorigenesis of renal cell carcinoma by regulating the m6A modification of PPAT PMID 35798250
Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors PMID 34710325
Esculentic acid, a novel and selective COX
SPD
Cardiomyocyte
Signal Peptide
Terbutryn 886
Nafcillin sodium monohydrate 7177
Enzalutamide inhibits PEX10 function and sensitizes prostate cancer cells to ROS activators PMID 39097593
The endocannabinoid system dual
Synthesis and biological evaluation of longanlactone analogues as neurotrophic agents PMID 29402744
Pharmacological Inhibition of the Psychiatric Risk Factor FKBP51 Has Anxiolytic Properties PMID 26085626
N
Cresyl diphenyl phosphate (a novel organophosphate ester) induces hepatic steatosis by directly binding to liver X receptor α From molecule action to risk assessment PMID 39612745
Neurophysiological signals as potential translatable biomarkers for modulation of metabotropic glutamate 5 receptors PMID 23831682
Disruption of axonal transport in Parkinson's disease the role of pathological α
Flavidulols C 117568
ATP 合酶 F1 亚基α（ATP5F1A）基因
Top Publications Citing MCE Products
Carnosic Acid against Lung Cancer Induction of Autophagy and Activation of Sestrin
Hemocyanin controls Vibrio levels in hemolymph by modulating intracellular ROS via p38 MAPK PMID 40852966
Chloronectrin 38965
Pseudotropine (β
The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium PMID 29606146
Cloning and characterization of a rabbit ortholog of human Galpha16 and mouse G(alpha)15 PMID 10571060
Pomalidomide
Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice PMID 22913271
POU6F1 cooperates with RORA to suppress the proliferation of lung adenocarcinoma by downregulation HIF1A signaling pathway PMID 35504868
Synthesis and identification of lithocholic acid 3
BDE 47 5436
ML218 1346233
Jacobine N
Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis
Calmodulin regulates the transcriptional activity of estrogen receptors. Selective inhibition of calmodulin function in subcellular compartments PMID 12419798
Zipalertinib 1661854
Phenyl Bis
Respiratory Syncytial Virus Fusion Protein Epitope
8RK64 2705841
Tissue repair
Evidence that the antiestrogen binding site is a histamine or histamine
Characterization of ferroptosis
二氢嘧啶脱氢酶（DPYD）基因
Novel amide derivatives as inhibitors of histone deacetylase design, synthesis and SAR PMID 18672316
Angiotensin Receptor
4
L
Bone Marrow
Cynandione A 168706
Novel PIKfyve/Tubulin Dual
Design, Synthesis, and In Vitro and In Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti
In vitro and in vivo assessment of eprociclovir as antiviral treatment against testudinid herpesvirus 3 in Hermann's tortoise (Testudo hermanni) PMID 30782569
N
Pks13
Restricticin 135357
Mfn1
Mammary Epithelial Cell
Siglecf
BCL2 相关 X，细胞凋亡调节因子（Bax）基因
Unfolding of acrylodan
The novel small molecule BH3 mimetic nobiletin synergizes with vorinostat to induce apoptosis and autophagy in small cell lung cancer PMID 37716621
GSK3368715 trihydrochloride 2227587
Galactose transport in Salmonella typhimurium PMID 190207
Macrophages originated IL
3
Valacyclovir
Loratadine. A reappraisal of its pharmacological properties and therapeutic use in allergic disorders PMID 7528133
MM 419447
Lactucin
IRAK4
Characterization of the cathepsin B
Aceclofenac 89796
DEHYDROEMETINE IN ACUTE AMOEBIASIS PMID 14217012
Cell Patterning Using Magnetic
Dapoxetine, a novel selective serotonin transport inhibitor for the treatment of premature ejaculation PMID 18360636
Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity PMID 40133308
Arachidonic acid
FGF2 Is Protective Towards Cisplatin
The alleviative effect of flavonol
BIM 23052
Three
Cediranib 288383
Formulation and in vitro/in vivo correlation of a drug
Dpysl2
Asparagine drives immune evasion in bladder cancer via RIG
Ngf
TMP780 1422053
A broad
Identifying polyamine related biomarkers in diagnosis and treatment of ulcerative colitis by integrating bulk and single
Mechanism of action and in vitro and in vivo activities of S
Ivermectin
PI3Kgamma Inhibitor Attenuates Immunosuppressive Effect of Poly(l
Constituents of the stem barks of Ailanthus altissima and their potential to inhibit LPS
Discovery and Characterization of Moracin C as an Anti
FGF1 attenuates sepsis
1β
Cd33
Loss
CC 115
NNC 26
Telisotuzumab vedotin 1714088
Inhibitory effects of armepavine against hepatic fibrosis in rats PMID 19723340
NF
Roles of transient receptor potential channel 6 in glucose
TA
RSPO1/R
Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease PMID 34343498
Pelecopan 2378380
MAL
Rational Design of a Novel 6 H
Fluoride Stimulates Anxiety
Targeting the mTOR Complex by Everolimus in NRAS Mutant Neuroblastoma PMID 26821351
15
NSC5844 (RE
Guaijaverin 22255
PF
BG00002
Galectin
Homovanillic acid 306
JAK3 抗体 (YA5408)（JAK3 Antibody (YA5408)）
Hypertonicity induces mitochondrial extracellular vesicles (MEVs) that activate TNF
Fimasartan 247257
(S)
Aberrant Super
MAPKK
ETD
Phosphodiesterase I 9025
The Proliferation Mechanism of Lactobacillus plantarum RB1 Stimulated by Stachyose PMID 28374137
Loading Intracranial Drug
Discovery of Thieno[2,3
14
Corynoxine 6877
Himandridine 15521
SARS
Isonicotinic acid
Discovery of potent and orally active tricyclic
A Capsicum annuum L. seed extract exerts anti
Evidence that a Novel Chalcone Derivative, Compound 27, Acts on the Epithelium Via the PI3K/AKT/Nrf2
MAPKK
BG00002
Panaxadiol acts as an HIF
Identification of a Novel Vascular Endothelial Growth Factor Receptor
AL
ASS1
2
TA
D
BoNT
CC260 2411088
Discovery of a Novel, Potent Spirocyclic Series of γ
TNKS
Toll
Testosterone sulfate (pyridinium) 34991
N
Assessing the trypanocidal potential of natural and semi
14
Dronedarone an amiodarone analogue PMID 15102590
Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use PMID 6376062
Interactions between host epithelial cells and Acinetobacter baumannii promote the emergence of highly antibiotic resistant and highly mucoid strains PMID 36227610
22(R)
Autophagy
TMPRSS2
STAT1 mediates the pro
Dacomitinib (PF
Fexapotide TFA (NX
Naphthol AS phosphate disodium salt 69815
PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses PMID 24352480
Mal
Epstein
Factors influencing antipyrine elimination PMID 332216
Sensory neurostimulation promotes stress resilience with frequency
Autophagy
Semi
Abcg1
APRIL and BCMA promote human multiple myeloma growth and immunosuppression in the bone marrow microenvironment PMID 27127303
Pachymic acid alleviates secondary lymphedema through the modulation of EETs level and the inhibition of lymphatic fibrosis PMID 40580744
YX862
PDE4
4
Gamendazole 877773
Antitumor activity of L
Lysine
R(+)
Indanesulfonamides as carbonic anhydrase inhibitors and anticonvulsant agents structure
Establishment of disulfidptosis
UK122 940290
L
Push
CSF2
Sacubitrilat impurity 34 (Standard)
mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies PMID 37906000
CREM
Synthetic Red Blood Cell
N6
Dimethyl phosphorothioate 1112
PCDHGA9 acts as a tumor suppressor to induce tumor cell apoptosis and autophagy and inhibit the EMT process in human gastric cancer PMID 29348665
Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes PMID 30036684
EZH2
DMA trihydrochloride 2095832
The effect of chitinase inhibitors, cyclo(Arg
(S)
HMGB1
Characterization of CD8 T Cell
3
Bulevirtide 2012558
Novel Cyclic Phosphinic Acids as GABAC ρ Receptor Antagonists Design, Synthesis, and Pharmacology PMID 24900248
Synthesis and biological evaluation of novel pentacyclic triterpene α
Polypodine B 18069
ATPase H+ 转运 V0 亚基 b（ATP6V0B）基因
Creatine
Iptacopan hydrochloride 1646321
Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification PMID 31972171
In
Quercetin
SAH
YK5 1268273
Lupeol induces apoptosis of glioma cells via governing ubiquitination
Raclopride tartrate
Alpha
Electroactive membranes enhance in
1,2,3
Calcein
Syntheses and antigestagenic activity of mifepristone derivatives PMID 19216549
A fast and specific fluorescent probe for thioredoxin reductase that works via disulphide bond cleavage PMID 31227705
CeDaD
The pharmacology of citalopram enantiomers the antagonism by R
m7GpppApG
Cisplatin
DDO
Dapsone
Trophoblast fusion in fetal growth restriction is inhibited by CTGF in a cell
TRK
S
Blocking protease
CCL20 and Beta
The SARS
Ifetroban sodium an effective TxA2/PGH2 receptor antagonist PMID 11484065
Poly(ethylene glycol) dimethacrylate (MW 550) 25852
Individual and combined mycotoxins deoxynivalenol, nivalenol, and fusarenon
ACP5 蛋白, Human (HEK293, His)
Activation of the clock gene TIMELESS by H3k27 acetylation promotes colorectal cancer tumorigenesis by binding to Myosin
7(8)
AL
Apo
Porcine circovirus 3 capsid protein induces autophagy in HEK293T cells by inhibiting phosphorylation of the mammalian target of rapamycin PMID 32633110
Discovery of pyrrolo[2,3
Population pharmacokinetics for danofloxacin in the intestinal contents of healthy and infected chickens PMID 31424100
Alternative pathway of bile acid biosynthesis contributes to ameliorate NASH after induction of NAMPT/NAD+/SIRT1 axis PMID 37315437
Untargeted Safety Pharmacology Screen of Blood
Rate
Oncometabolite fumarate facilitates PD
Gruticibart 2704554
Magnificines A and B, Antimicrobial Marine Alkaloids Featuring a Tetrahydrooxazolo[3,2
Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A PMID 33310292
Cannflavins A and B with Anti
Anti
Establishment and drug resistance characterization of paired organoids using human primary colorectal cancer and matched tumor deposit specimens PMID 39495391
L
Cystic fibrosis transmembrane conductance regulator mediates tenogenic differentiation of tendon
4
N
Discovery of a novel third
Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells PMID 28763460
N
Immunoregulatory effects of Tetrastigma hemsleyanum polysaccharide via TLR4
Inhibition of MyD88 attenuates angiotensin II
A saponin from astragalus promotes pancreatic ductal organoids differentiation into insulin
Natural product preferentially targets redox and metabolic adaptations and aberrantly active STAT3 to inhibit breast tumor growth in vivo PMID 36473850
Synergistic Effect of Carboplatin and Piroxicam on Two Bladder Cancer Cell Lines PMID 28373436
[Tyr0] Corticotropin Releasing Factor, ovine 83930
Targeting CCL2
Characterization of (2S,4R)
Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer PMID 30055645
Autophagy inhibits nuclear factor kappa B and mitogen
Beneficial effects of combining nilotinib and imatinib in preclinical models of BCR
Assessment of tryptophol genotoxicity in four cell lines in vitro a pilot study with alkaline comet assay PMID 21421532
CD73+ extracellular vesicles inhibit angiogenesis through adenosine A2B receptor signalling PMID 32489531
mmu
Tesirine intermediate
Ox4 2089058
染色体 1A 的结构维护（SMC1A）基因
The structure of anthracycline derivatives determines their subcellular localization and cytotoxic activity PMID 24900668
Anatumomab mafenatox 1370261
Tropisetron attenuates high glucose
Tricyclic 3,4
Z
AS1892802 928320
Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase
CDD
Identification of N
Andrographidine C 113963
Discovery of 4
Discovery of N
Anti
The effect of topical l
Apraclonidine hydrochloride (ALO 2145，盐酸安普乐定)
A quality
Monopropyl phthalate 4376
VE822
SUCLG1 deficiency
Cryptolepinone 178884
Enhanced protein degradation by intracellular delivery of pre
Drugging an undruggable pocket on KRAS PMID 31332011
Advances in tetrahydropyrido[1,2
Discovery of a tetrahydroisoquinoline
OR
3'
Deferasirox
Pralatrexate 146464
Effects of antiparkinsonian drugs on muscarinic receptor binding in rat brain, heart and lung PMID 3353357
The Effect of Sildenafil on Recuperation from Sciatic Nerve Injury in Rats PMID 27403391
The scale of zebrafish pectoral fin buds is determined by intercellular K+ levels and consequent Ca2+
hypoxia
A498
HER2/CD340 蛋白, Human (Biotinylated, HEK293, His)
Deoxyvasicinone 530
The whitening effect of cuscutin responsible for traditional use of Bergenia purpurascens PMID 38382653
Generation of Bona Fide Human Induced Trophoblast Stem Cells by Direct Reprogramming of Term Umbilical Cord Cells PMID 39796127
KS10076, a chelator for redox
Differential effects of ABT
PROTAC SMARCA2/4
2,2
Microenvironmental CXCL12 deletion enhances Flt3
CD31 as a Therapeutic Target in Atherosclerosis PMID 32324506
Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat PMID 7956608
(Rac)
Anti
CD248 as a novel therapeutic target in pulmonary arterial hypertension PMID 32997414
Enhanced engraftment and immunomodulatory effects of integrin alpha
Mechanism of annexin A1/N
Buflomedil hydrochloride 35543
Aldehyde dehydrogenase 2 activation ameliorates cyclophosphamide
Ivabradine impurity 1
Anandamide 94421
Chronic lymphoid leukemia
Methylkushenol C
Veratrole
Sulfane sulfur probe 4 1810731
Chrysin induces autophagy
myofibroblasts
SEL24
Suppression of argatroban
Methoxyacetic acid and ethoxyacetic acid inhibit mitochondrial function in vitro PMID 3271880
Cytosporone B 321661
Fedratinib hydrochloride hydrate 1374744
龙胆山酮酚
Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure
含富含亮氨酸的重复序列 32（LRRC32）基因
Function and effect of bone morphogenetic protein
Sarizotan 351862
MtTMPK
S1P/S1PR2 promote pancreatic stellate cell activation and pancreatic fibrosis in chronic pancreatitis by regulating autophagy and the NLRP3 inflammasome PMID 37169277
Heterogeneity in sarcoma cell lines reveals enhanced motility of tetraploid versus diploid cells PMID 28035071
Enpp
D
Aflatoxin B1
α
Cyclopeptide Inhibitors Target the N
KRAS G12C inhibitor 23
Periostin promotes arterial calcification through PPARγ
NA/Neuraminidase 蛋白, H1N2 (QAX25989, HEK293, His)
SUP
IL
Auraptene attenuates gastritis via reduction of Helicobacter pylori colonization and pro
Proteomic screening identifies RPLp2 as a specific regulator for the translation of coronavirus PMID 36632964
PDCD4 promotes inflammation/fibrosis by activating the PPAR‑γ/NF‑κB pathway in mouse atrial myocytes PMID 39301631
Astrocytic histone deacetylase 2 facilitates delayed depression and memory impairment after subarachnoid hemorrhage by negatively regulating glutamate transporter
D
Synthesis and anti
Proadifen
L
Design of chimeric peptide ligands to galanin receptors and substance P receptors PMID 1328099
Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor PMID 7639848
ROCK2抑制剂、基因
cis
cis
erb
Cetylpyridinium chloride (西吡氯铵)
Diplacone Isolated from Paulownia tomentosa Mature Fruit Induces Ferroptosis
AZD1152, a selective inhibitor of Aurora B kinase, inhibits human tumor xenograft growth by inducing apoptosis PMID 17575233
Azeliragon
p,p'
Glochidiol 6610
Tenofovir
Stabilization of Hypoxia Inducible Factor
Safety and tolerability of the γ
Quercetin improves nonalcoholic fatty liver by ameliorating inflammation, oxidative stress, and lipid metabolism in db/db mice PMID 31452288
Trifloxystrobin 141517
Effects of propyl paraben on the male reproductive system PMID 12419695
Ginsenoside F2
IL
Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro PMID 3986806
巴瑞克替尼 d
Enhancer of Zeste Homolog 2 Protects Mucosal Melanoma from Ferroptosis via the KLF14
5
Pretreatment with resveratrol ameliorate trigeminal neuralgia by suppressing matrix metalloproteinase
巴瑞替尼
Annexin A10 contributes to chronic constrictive injury
Human serum albumin in cardiovascular diseases PMID 29680174
Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells PMID 26257704
Hypoxia induces actin cytoskeleton remodeling by regulating the binding of CAPZA1 to F
Bentazone 25057
IL
NAPAP 137171
JNJ
Col3a1
CEACAM3 蛋白, Human (HEK293, His)
In
Sonic hedgehog regulates the pathfinding of descending serotonergic axons in hindbrain in collaboration with Wnt5a and secreted frizzled
1
Discovery of novel 4
Neuroprotective effect of astragalin via activating PI3K/Akt
SHP2/CDK4
Inhibition of human immunodeficiency virus type 1 by niclosamide through mTORC1 inhibition PMID 32529067
FQ 190838
retinoic
From vasotocin to stress and cognition PMID 19837060
hsa
Primaquine hybrids as promising antimycobacterial and antimalarial agents PMID 29220797
Dexamethasone disrupts intracellular pH homeostasis to delay coronavirus infectious bronchitis virus cell entry via sodium hydrogen exchanger 3 activation PMID 40340398
Lithium Chloride Facilitates Autophagy Following Spinal Cord Injury via ERK
Pharmacological profile of KUL
Design and Synthesis of Novel PET Radiotracers for Imaging Sphingosine
Forchlorfenuron 68157
Bacillus cereus cereolysin O induces pyroptosis in an undecapeptide
1
AR
5,15
miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells PMID 20439489
MRS
Progesterone activates GPR126 to promote breast cancer development via the Gi pathway PMID 35394864
serpin 家族成员 2（SERPINI2）基因
Ex 380
Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats PMID 12145156
Multi
Postchallenge administration of brincidofovir protects healthy and immune
JAM
NKG2A
Sulfo
IRE1
Oleanonic acid ameliorates pressure overload
小核核糖核蛋白 U1 亚基 70（SNRNP70）基因
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