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Concerning the photophysics of fluorophores towards tailored bioimaging compounds a case study involving S100A9 inflammation markers PMID 37303026
Inhibition of dengue virus RNA synthesis by an adenosine nucleoside PMID 20457821
An acetyl
Novel sulfonamide
3
Lsp1
V10XA53
YAP/Aurora A
CHIKV
PIK3CA mutation affects the proliferation of colorectal cancer cells through the PI3K
钠离子通道阻断剂库
TRAF4 Promotes the Proliferation of Glioblastoma by Stabilizing SETDB1 to Activate the AKT Pathway PMID 36077559
Polyketides from the littoral plant associated fungus Pseudallescheria boydii PMID 23964677
Peiminine Attenuates Acute Lung Injury Induced by LPS Through Inhibiting Lipid Rafts Formation PMID 32152924
Progress in the development and application of small molecule inhibitors of bromodomain
Loss of miR
Lactate transported by MCT1 plays an active role in promoting mitochondrial biogenesis and enhancing TCA flux in skeletal muscle PMID 38924407
V10XA53
Equilin 3
Disrupting YAP1
Multicargo
PF4V1 蛋白, Human (HEK293, Fc)
Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11
4,4'
Chikusetsu (CHI) triggers mitochondria
Overview of medically important antifungal azole derivatives PMID 3069196
Actions of D and L forms of 2
Aaptamine 85547
Rigosertib induces cell death of a myelodysplastic syndrome
Cyclovirobuxine D alleviates aldosterone
Identification and optimization of new dual inhibitors of B
Curcumin protects the pancreas from acute pancreatitis via the mitogen‑activated protein kinase signaling pathway PMID 31432122
Interleukin
Methylene blue accelerates liquid
Targeting Viral Ion Channels A Promising Strategy to Curb SARS
Formycin triphosphate as a probe for the ATP binding site involved in the activation of guanylate cyclase PMID 1358664
DNJNAc (2
Nucleoside Transporters
mmu
NMDA
SIGLEC15
Establishing dorsal
吡咯并喹啉苯醌钠盐 (Standard)
Diminazene aceturate uses different pathways to induce relaxation in healthy and atherogenic blood vessels PMID 36566945
Veliflapon 128253
半乳糖
CSF1R 蛋白, Mouse (HEK293, Fc)
FBP1 controls liver cancer evolution from senescent MASH hepatocytes PMID 39743585
SGX 942
The iron chelator Dp44mT causes DNA damage and selective inhibition of topoisomerase IIalpha in breast cancer cells PMID 19176392
Leupeptin 55123
Nucleoside Transporters
2
2
H
Sorbicillin 79950
Fmoc
Naloxone fluorescein acetate
Interrogating the bioactive pharmacophore of the latrunculin chemotype by investigating the metabolites of two taxonomically unrelated sponges PMID 18942825
The anti
MDA
mTOR
脂肪酸结合蛋白 1（FABP1）基因
insulin sensitization
基质金属肽酶 28（MMP28）基因
Diclofenac
Resveratrol reduces DRP1
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis PMID 37059819
Direct and indirect cellular effects of aspartame on the brain PMID 17684524
SGLT1 in pancreatic α cells regulates glucagon secretion in mice, possibly explaining the distinct effects of SGLT2 inhibitors on plasma glucagon levels PMID 30416006
Pomalidomide
MDA
insulin sensitization
Ferric phosphate 10045
L
The effect of 17 alpha
IDO
Flavonoids from genista ephedroides PMID 9834164
mTOR
OR
Differential expression of IL
Quantitative, Wide
Identification and Validation of Alkaliptosis Resistance
Discovery of novel 9
N,N
Fmoc
DSG
Cytotoxic steroidal saponins from Trillium kamtschaticum PMID 28454671
memory impairment
Interleukin 25 regulates type 2 cytokine
Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1
Circ_0079480 facilitates proliferation, migration and fibrosis of atrial fibroblasts in atrial fibrillation by sponing miR
喹啉丁聚半乳糖酸酯
Dihydroartemisinin breaks the positive feedback loop of YAP1 and GLUT1
A combat with the YAP/TAZ
EGF signaling promotes the lineage conversion of astrocytes into oligodendrocytes PMID 35508991
Buyang Huanwu Decoction restores the balance of mitochondrial dynamics after cerebral ischemia
Agranulocytosis and liver damage associated with pyrazinobutazone with evidence for an immunological mechanism PMID 2600947
African Swine Fever Virus pI215L Inhibits Type I Interferon Signaling by Targeting Interferon Regulatory Factor 9 for Autophagic Degradation PMID 35972295
Metabotropic Glutamate Receptors As Emerging Targets for the Treatment of Schizophrenia PMID 35246479
AG
NOD
HDAC1/2
5
Tea polyphenol 84650
ATP2A1/SERCA1 抗体 (YA3519)（ATP2A1/SERCA1 Antibody (YA3519)）
Doramapimod hydrochloride 1283526
Azidocillin treatment of enterococcal septicemia PMID 4341815
m
DEAD
Inhibition of Heme Oxygenase 1 Suppresses Growth, Migration, and Invasion, and Regulates Tumor
2
(±) Anabasine hydrochloride
Identification of potential pathogenic hepatic super
Isotachioside 31427
(Z)
Critical role of G protein
钾钙激活通道亚家族 N 成员 4（KCNN4）基因
Conserved immuno
Trimethoprim a review of its antibacterial activity, pharmacokinetics and therapeutic use in urinary tract infections PMID 7049657
Levonorgestrel inhibits proliferation and induces apoptosis in uterine leiomyoma cells PMID 20705162
DM
JV8 2841716
Role of EphA2
Testicular Lmcd1 regulates phagocytosis by Sertoli cells through modulation of NFAT1/Txlna signaling pathway PMID 32840323
Atf3 Rat Pre
MCE
RGS14 蛋白, Human (His)
Cryptosporioptide A 1647101
Stress
AM281 (Standard)
A multifunctional anti
Tilorone confers robust in vitro and in vivo antiviral effects against severe fever with thrombocytopenia syndrome virus PMID 35234618
Small round cell sarcoma tumoroid biobank reveals CIC DUX4 sarcoma vulnerability to MCL
VEGF
EBNA1 Inhibitors
1,2
Hydrophilic polymer drug from a derivative of salicylic acid synthesis, controlled release studies and biological behavior PMID 15468251
AD
Chronic Dietary Exposure to Environmental Levels of Glyphosate Increases the Risk of Reproductive Dysfunction in Male Mice PMID 40698942
rno
Cav1
CGP 28014
Methyl lucidenate Q 648430
Tinuvin
Structure
Magnolol, a Natural Polyphenol, Attenuates Dextran Sulfate Sodium
Insulin
S116836 1257628
Sodium 2
N
RAP1
EGFR phosphorylates DNAJB1 to suppress α
hippocampal
Accelerated activation of SOCE current in myotubes from two mouse models of anesthetic
Discovery, synthesis and characterization of a highly muscarinic acetylcholine receptor (mAChR)
4
CXCL9
Thymol and menthol as anaesthetics for short transportation of zebrafish larva PMID 40736925
Pdpk1 Mouse Pre
2
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension PMID 36507843
PEDV inhibits HNRNPA3 expression by miR
Sapropterin (BH4) Aggravates Autoimmune Encephalomyelitis in Mice PMID 33844153
Bioactive Metabolites from the Fruits of Psoralea corylifolia PMID 25710081
Injectable self
The Pathogenic Role of Long Non
DU717 59943
Synthesis and anti
In vitro inhibition of glycogen
5
In Vitro and In Vivo Antimicrobial Activity of Antibiotic
Exploration of novel thiobarbituric acid
Mechanism by which hydrogen
1
Dysregulated NOX1
CXC 基序趋化因子配体 12（CXCL12）基因
A WFS1 variant disrupting acceptor splice site uncovers the impact of alternative splicing on beta cell apoptosis in a patient with Wolfram syndrome PMID 39520565
Bacterial amyloid curli activates the host unfolded protein response via IRE1α in the presence of HLA
Menthol glucuronide 79466
Activity of Aztreonam in Combination with Avibactam, Clavulanate, Relebactam, and Vaborbactam against Multidrug
Wnt5b
Nimotuzumab 780758
Phenylmethanamine
trans
LSD1
7
Human expandable pancreatic progenitor
Evidence for inhibitory effects of flupirtine, a centrally acting analgesic, on delayed rectifier k(+) currents in motor neuron
EP4 receptor agonist 2 493035
静脉血栓栓塞
Electrochemical sensor toolkit for simultaneous glutamate detection at edge of cleft and peri
Novel 3,4
MDA
Antibiotic WB 247919
Itaconate is an anti
Veillonella intestinal colonization promotes C. difficile infection in Crohn's disease PMID 40848719
The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression PMID 39613801
Non
Pathogenic role of acyl coenzyme A binding protein (ACBP) in Cushing's syndrome PMID 39578649
A novel series of teriflunomide derivatives as orally active inhibitors of human dihydroorotate dehydrogenase for the treatment of colorectal carcinoma PMID 35640328
East Indian Sandalwood Oil Is a Phosphodiesterase Inhibitor A New Therapeutic Option in the Treatment of Inflammatory Skin Disease PMID 29593534
Quercetin Induces Apoptosis Through Downregulating P4HA2 and Inhibiting the PI3K/Akt/mTOR Axis in Hepatocellular Carcinoma Cells An In Vitro Study PMID 40347062
Cefditoren a clinical overview PMID 36853812
A novel label
Senolytic Peptide FOXO4
Lysozyme chloride 9066
IL
DSPE
DNA G
Ubiquitination of Src promotes its secretion via small extracellular vesicles PMID 32085898
Inhibition of matrix metalloproteinase expression and cellular invasion by NF
Rubusoside 64849
membrane
Bioisosteres of the Phenyl Ring Recent Strategic Applications in Lead Optimization and Drug Design PMID 34591488
Anti
VSIR
N
5
Methyl vanillate 3943
FOXQ1/NDRG1 axis exacerbates hepatocellular carcinoma initiation via enhancing crosstalk between fibroblasts and tumor cells PMID 29248714
Chemical constituents of the roots of Piper sarmentosum PMID 16462055
Lipid peroxidation inhibitory compounds from daylily (Hemerocallis fulva) leaves PMID 15172183
Increased Fascin1 and Pak1 Expressions Enhance Age
ZFP541 and KCTD19 regulate chromatin organization and transcription programs for male meiotic progression PMID 37921559
Pharmacologically inhibiting phosphoglycerate kinase 1 for glioma with NG52 PMID 32737469
Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID
PDZK1 相互作用蛋白 1（PDZK1IP1）基因
Fucosylated Glycosaminoglycan Oligosaccharide HS14, Derived from Sea Cucumbers, Is a Novel Inhibitor of Platelet Toll
Diaporthin and Orthosporin from the Fruiting Body of Daldinia concentrica PMID 24039468
Transcriptional landscape of human neuroblastoma cells in response to SARS
Il10 Rat Pre
Uracil
Alirocumab 1245916
Budesonide 51333
Gardenoside suppresses the pain in rats model of chronic constriction injury by regulating the P2X3 and P2X7 receptors PMID 29932348
Apple polysaccharide prevents from colitis
SGLT2 inhibitors protect against diabetic cardiomyopathy and atrial fibrillation through a CaMKII independent mechanism PMID 39386626
Reduction of epithelial secretion in male rat distal colonic mucosa by bile acid receptor TGR5 agonist, INT
15α
Karrikins discovered in smoke trigger Arabidopsis seed germination by a mechanism requiring gibberellic acid synthesis and light PMID 19074625
Suppressing long noncoding RNA OGRU ameliorates diabetic retinopathy by inhibition of oxidative stress and inflammation via miR
Nonpeptide Urotensin
RP
Raclopride (雷氯必利)
(S,S)
PF
Evaluation of an Ussing Chamber System Equipped with Rat Intestinal Tissues to Predict Intestinal Absorption and Metabolism in Humans PMID 35733077
(E)
Ponatinib hydrochloride 1114544
Toxic Effects of Glyphosate on the Nervous System A Systematic Review PMID 35562999
Isoflurane Attenuates Cerebral Ischaemia
Phaseollidin 37831
Diltiazem hydrochloride 33286
Enhancement of acute phase and inhibition of chronic phase of experimental autoimmune neuritis in Lewis rats by intranasal administration of recombinant mouse interleukin 17 potential immunoregulatory role PMID 10785455
Milk thistle's active components silybin and isosilybin novel inhibitors of PXR
Src homology region 2
Nicotine
MCE
Dexmedetomidine regulates the SIRT3
Smac mimetic promotes TNF
Applications of contemporary tools to measure plasma protein binding of targeted protein degraders PMID 40286535
3D freeform printing of silk fibroin PMID 29550442
Preclinical safety profile of a liver
Pentose phosphate recycling driven by Gli1 contributes to chemotherapy resistance in cancer cells PMID 40090571
Z
Amlodipine maleate (Standard)
无水硫酸钠,meets analytical specification of Ph. Eur. BP USP (Standard)
In vivo antitumor activity of NVP
Distinct substrate specificities of the three catalytic subunits of the Trichomonas vaginalis proteasome PMID 39589076
Increased protein expression of interleukin
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome
Characterisation of neuroprotective efficacy of modified poly
TC
Crinamine Induces Apoptosis and Inhibits Proliferation, Migration, and Angiogenesis in Cervical Cancer SiHa Cells PMID 31527550
Zuberitamab 2251143
Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia
α
Methyl palmitoleate 1120
MEK nuclear localization promotes YAP stability via sequestering β
Choline tosylate 55357
ATRA promotes PD
Isoescin Ie 1613506
The Expanding Role of the BCL6 Oncoprotein as a Cancer Therapeutic Target PMID 27881582
A phycocyanin derived eicosapeptide attenuates lung fibrosis development PMID 34280398
4
Antinociceptive properties of bergenin PMID 21939182
GFER
Antiproliferative activity and apoptosis inducing effects of nitric oxide donating derivatives of evodiamine PMID 27178387
NSC104800
amphoteric
Reelin Promotes Cisplatin Resistance by Induction of Epithelial
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice PMID 36889319
Development of Macrocyclic Neurotensin Receptor Type 2 (NTS2) Opioid
MCE
Design and evaluation of 1,2,3
FGFR
AC
Alternative to LRRK2
Schleicheol 2 256445
1,8
LIGHT/TNFSF14 蛋白, Human (HEK293, mFc)
Chloroquine Restores eNOS Signaling in Shunt Endothelial Cells via Inhibiting eNOS Uncoupling PMID 39941119
Ichorcumab 2589583
Synthesis and biological evaluation of trans 6
电压门控质子通道
生物毒素化合物库
CDK7
Why delta
AZD 6738
三乙酸甘油酯
A supported liquid extraction LC
Exposure to permethrin promotes high fat diet
Fmoc
GNE
Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University PMID 38302552
Inhibiting Cyclin
AA43279 354812
Quantitation of fibroblast activation protein (FAP)
Co
Primary cilia prevent activation of the cGAS
KN
Effect of BN 50727 on pathological findings and tissue platelet activating factor levels during ileal ischemia in newborn piglets PMID 8986985
CP
Quantitative assessment of Tet
CTRP9 Enhances Efferocytosis in Macrophages via MAPK/Drp1
JAK/STAT Cytokine Signaling at the Crossroad of NK Cell Development and Maturation PMID 31781102
Palbociclib induces activation of AMPK and inhibits hepatocellular carcinoma in a CDK4/6
Deltamethrin
Rack1
Transport and Interactions of Co
Exploring Indole
Development of PROTACS degrading KRAS and SOS1 PMID 39055890
MCE
Chemokine receptor
Synthesis and biological evaluation of cyclopentane
TOPOI/PARP
Neoenactin M2 108334
TUBB4A Inhibits Glioma Development by Regulating ROS
TLR4
MELK is not necessary for the proliferation of basal
Verapamil as a culprit of palbociclib toxicity PMID 29523051
M6A
IL
Clinical and microbiological effects of levofloxacin in the treatment of chronic periodontitis a randomized, placebo
A
GLUT4
Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6 PMID 28231796
GW856464
ASK1
Anti
Gevokizumab 1129435
Cyanine 5 Tyramide 1431148
Efficacy of Ibrexafungerp (SCY
alpha
Polyvinylpyrrolidone K30 9003
Irisin alleviates steroid
Melatonin Regulates lncRNA NEAT1/miR
Novel phosphonate analogs of sulforaphane Synthesis, in vitro and in vivo anticancer activity PMID 28342398
epi
CXCL3 overexpression affects the malignant behavior of oral squamous cell carcinoma cells via the MAPK signaling pathway PMID 34392586
Synthesis and antiparasitic activity of 1H
Pathogenic phosphorylation of linear ubiquitin machinery causes inflammasome sensor degradation PMID 40944911
Anticancer and anti
Role of Serum Ferritin, D
An allosteric kinase inhibitor binds the p21
Cytidine 5'
VEGFR2 signal pathway
HY
Pharmacokinetics and tolerability of SRT2104, a first
MCOPPB trihydrochloride 1108147
(S)
MicroRNA
Anti
Rifaquizinone 922717
Galantamine inhibits beta
factor
Immunomodulatory Effects of Cinobufagin on Murine Lymphocytes and Macrophages PMID 26664411
DDB1 和 CUL4 相关因子 4（DCAF4）基因
Effects of L
Pharmacological inhibition of Kir4.1 evokes rapid
Synthesis and biological evaluation of conformationally flexible as well as restricted dimers of monastrol and related dihydropyrimidones PMID 21620531
Methyl
Synthesis and anticancer activity of various 3'
Schwann cell
Alpha
Cholesterol
Assessing different thiazolidine and thiazole based compounds as antileishmanial scaffolds PMID 33091607
Ethyl pyruvate 617
The effect of small molecule inhibitor NSC348884 on nucleophosmin 1
AOC
EGR1 promotes the cartilage degeneration and hypertrophy by activating the Krüppel
Validation of formamide as a detubulation agent in isolated rat cardiac cells PMID 12234828
PB 4188
Non
Virtual Screening Directly Identifies New Fragment
Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue PMID 17959711
Synthesis and anticancer activity of a novel class of flavonoids 2,4
Hydroxysafflor yellow A (HYSA) inhibited the proliferation and differentiation of 3T3
Hydroxydaunorubicin hydrochloride
TNBC
Atf3 Mouse Pre
Phospholipase C gamma 1 抗体 (YA3851)（Phospholipase C gamma 1 Antibody (YA3851)）
PROTAC BRD9 Degrader
2
hsa
VT
5
Doxapram stimulates dopamine release from the intact rat carotid body in vitro PMID 7617294
Neutrophil extracellular traps potentiate effector T cells via endothelial senescence in uveitis PMID 39846254
Mechanisms of colon toxicity induced by long
Specific expression of proton
SGD
rac 5
Clathrin
Biotin
Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin
Levoleucovorin as replacement for leucovorin in cancer treatment PMID 23032661
RBM10 inhibits pancreatic cancer development by suppressing immune escape through PD
Glimepiride sulfonamide 119018
Neoanhydropodophyllol 62287
1
Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h
CEACAM5 蛋白, Human (Biotinylated, HEK293, C
Phaseollin 13401
Carminic acid supplementation protects against fructose
Pam
Consumption of Saturated Fatty Acids
The effects of tegaserod, a 5
Promoting effect and immunologic role of secretogranin II on bladder cancer progression via regulating MAPK and NF
Molecular insights and functional analysis of isocitrate dehydrogenase in two gram
Amino acid composition and sequence of kassinin, a tachykinin dodecapeptide from the skin of the African frog Kassina senegalensis PMID 891753
Combined inhibition of RAD51 and CHK1 causes synergistic toxicity in cisplatin resistant cancer cells by triggering replication fork collapse PMID 39239809
Meclizine Improves Endometrial Repair and Reduces Simulated Menstrual Bleeding in Mice with Induced Adenomyosis PMID 38367751
Tacrine hydrochloride (hydrate) (盐酸他克林水合物)
2
Simlukafusp alfa 1776942
巴柑檬提取物 (Citrus bergamia)
Evaluation of anti
EST64454 hydrochloride 1950569
Endogenous Replication Stress Marks Melanomas Sensitive to CHEK1 Inhibitors In Vivo PMID 29535131
抑胃多肽（GIP）基因
Bepranemab 2244960
15, 16
Antibacterial agent 202 3035899
Acrylodan 86636
Deoxypyridinoline 83462
Effects of olanexidine gluconate on preoperative skin preparation an experimental study in cynomolgus monkeys PMID 28516852
The central melanocortin system directly controls peripheral lipid metabolism PMID 17885689
Co
Metabolic reprogramming by Zika virus provokes inflammation in human placenta PMID 32528049
Cucurbitane glycosides from the fruit of Siraitia grosvenori and their effects on glucose uptake in human HepG2 cells in vitro PMID 28317764
Phlorizin attenuates lupus nephritis via upregulating PI3K/Akt pathway
Valproic acid is a novel activator of AMP
Novel 1,2,5
Overexpression of Toll
Synthesis and Validation of the First Cell
Role of Phenylalanine in the Formation of Parent and Oxygenated Polycyclic Aromatic Hydrocarbons in Baking Systems PMID 40680198
PERK signaling through C/EBPδ contributes to ER stress
Synthesis of 15R
Redox Cascade in Chicken Skeletal Muscle SELENOT Suppression in Selenium Deficiency Triggers Disulfidptosis via mtROS
The autoimmune encephalitis
2
Integrated serum pharmacochemistry with network pharmacology and pharmacological validation to elucidate the mechanism of yiqitongmai decoction (YQTMD) against myocardial infarction PMID 38750989
Licaminlimab 1688648
Effect of structural modifications in the C7
5
CD43 抗体 (YA802)（CD43 Antibody (YA802)）
TAAR1 Regulates Purinergic
Golgi dispersal in cancer stem cells promotes chemoresistance of colorectal cancer via the Golgi stress response PMID 38879509
Optimization of a Dibenzodiazepine Hit to a Potent and Selective Allosteric PAK1 Inhibitor PMID 26191365
PRMT5 activates KLF5 by methylation to facilitate lung cancer PMID 37461162
Takeda
TFRC 蛋白, Human (HEK293, hFc)
Tulobuterol patch maintains diaphragm muscle contractility for over twenty
Toll样受体 3（Tlr3）基因
Broccoli rapid selection of an RNA mimic of green fluorescent protein by fluorescence
Orally Deliverable Microalgal
Quinalizarin 81
Bioactive steroidal alkaloids from Buxus macowanii Oliv PMID 25528196
Oxidized DJ
Peroxiredoxin 1, restraining cell migration and invasion, is involved in hepatocellular carcinoma recurrence PMID 29377617
WNK 赖氨酸缺陷型蛋白激酶 1（WNK1）基因
Modeling synovial sarcoma metastasis in the mouse PI3'
Z
Two antimicrobial alkaloids from heartwood of Liriodendron tulipifera L PMID 807704
SIRT1 restores mitochondrial structure and function in rats by activating SIRT3 after cerebral ischemia/reperfusion injury PMID 38767771
OSI
Influenza A virus dissemination and infection leads to tissue resident cell injury and dysfunction in viral sepsis PMID 40367638
Uric acid inhibits HMGB1
Echinosporin (XK
Stromal Senescence following Treatment with the CDK4/6 Inhibitor Palbociclib Alters the Lung Metastatic Niche and Increases Metastasis of Drug
Effects of retinoic acid receptor
zoxamide
Deoxycytidine triphosphate
4
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II
tert
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