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Potassium acetate
Antibiotic inhibition of RNA catalysis neomycin B binds to the catalytic core of the td group I intron displacing essential metal ions PMID 9737922
VE 822
rel
Ganoderic acid C1
Raffinose 512
靶向酪氨酸的共价片段库
NKG2D/CD314 蛋白, Human (sf9, His)
DSPE
uPAR 蛋白, Mouse (HEK293, His
Retinoic Acid Receptor gamma 抗体 (YA1860)(Retinoic Acid Receptor gamma Antibody (YA1860))
白血病/淋巴瘤/骨髓瘤 (Leukemia/Lymphoma/Myeloma)
R207910
Discovery of C
lepidota
METTL8 links mt
B7
Sodium oxalate,ACS,99.5% 62
MCE
IDOR
MCMB
Kininogen
[1, 8]
Lycetamine 60209
柯萨奇病毒腺病毒受体 (Coxsackievirus and Adenovirus Receptor (CXADR))
NBI
Inakalant
Epsom salts (Pharmaceutical primary standard, USP)
Autophagy Inhibitor
SRTCX
Cyclopiazonic acid 18172
Ylangenyl acetate (乙酸亚芳基酯)
CMKLR1 antagonist 1 3033101
线粒体外膜转位酶 22(TOMM22)基因
Bis
Selectivity of atipamezole, yohimbine and tolazoline for alpha
Attenuation of doxorubicin
miR
4’
Ilicic acid
CDC20 Human Pre
hsa
Oxidation of Reduced Graphene Oxide via Cellular Redox Signaling Modulates Actin
Fisetin inhibits the proliferation, migration and invasion of pancreatic cancer by targeting PI3K/AKT/mTOR signaling PMID 34821587
Ifnb1
MRS 2578 (Standard)
Interleukin
Posdinemab 2517973
Inactivation of Wnt signaling by a human antibody that recognizes the heparan sulfate chains of glypican
Highly reproducible and cost
Lifr Mouse Pre
Sailuotong Capsule Prevents the Cerebral Ischaemia
1,2,3,6,7,8
Nicotinamide mononucleotide ameliorates hypertriglyceridemia pancreatitis via NAD+/SIRT1
古塞库单抗
N,N
Scutellarein alleviates osteoarthritis progression through the PI3K/Akt/NF
Hedgehog agonist 1 946002
PPM1B degradation mediated by TRIM25 ubiquitination modulates cell cycle and promotes gastric cancer growth PMID 39979355
Doxorubicinone 24385
NSF
The mechanism of m6A methyltransferase METTL3
Cap2 Rat Pre
Downregulating DNA methyltransferase 3B by suppressing the PI3K/Akt signaling pathway enhances the chemosensitivity of glioblastoma to temozolomide PMID 38368287
STAT1 Human Pre
CD40 蛋白, Rhesus Macaque (HEK293, His)
Structure
Mammalian cells use the autophagy process to restrict avian influenza virus replication PMID 34107256
Effects of trimebutine maleate on colonic motility through Ca²+
HDAC6
A
KSQ
高效氟氯氰菊酯
SWI/SNF 相关、基质相关、肌动蛋白依赖性染色质调节因子,亚科 e,成员 1(SMARCE1)基因
PHX1149
Trehalose protects against cisplatin
Fispemifene 341524
重组神经节苷脂内切糖苷酶II
GSK
ALKBH5/MAP3K8 axis regulates PD
Benzoin methyl ether
β
NADPH oxidase
Exploration of novel pyrrolo[2,1
L
Towards protein production and application by using Chlorella species as circular economy PMID 31203183
Mechanism for controlled assembly of transcriptional condensates by Aire PMID 39169234
HSPA8 inhibitors augment cancer chemotherapeutic effectiveness via potentiating necroptosis PMID 38959101
IFN
Transfluthrin (Standard)
Deubiquitinase
rel
TFCP2L1 Human Pre
metabolic analysis
Conditioned medium from induced pluripotent stem cell
Quinidine hydrochloride
Con
5,7
LXRβ
WRN inhibitor 2
Neuroprotective agent
BGLT3
Divin a small molecule inhibitor of bacterial divisome assembly PMID 23738839
myelination
PDC
Thy
3
NLRP3 regulates ferroptosis via the JAK2/STAT3 pathway in asthma inflammation Insights from in vivo and in vitro studies PMID 39426227
signal
Sensing of endogenous retroviruses
ADH
Paramethasone
盐酸庚胺醇
Vosilasarm 1182367
Ribosomal S6 Kinase (RSK)
PROTAC PI3K/110β degrader
FITC
Rho
Rho
Rho
Polyoxyethylene (2) stearyl ether (Polyethylene glycol octadecyl ether (n=2))
Vinculin haploinsufficiency impairs integrin
ROK
ROCK
FLT3/CHK1 ligand
Indirubin
BRD9 status is a major contributor for cysteine metabolic remodeling through MST and EAAT3 modulation in malignant melanoma PMID 38070581
卢比替定
thrombus resolution
POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1
MAT2A
A Genome
Efficient targeted insertion of large DNA fragments without DNA donors PMID 35228726
(Rac)
Jaceidin
Oncogenic enhancers drive esophageal squamous cell carcinogenesis and metastasis PMID 34294701
3 H
Mca
Hormonal Regulation of Semaphorin 7a in ER+ Breast Cancer Drives Therapeutic Resistance PMID 33122307
recognition specificity
insulin
MYC status as a determinant of synergistic response to Olaparib and Palbociclib in ovarian cancer PMID 30898650
Chalcone synthase is ubiquitinated and degraded via interactions with a RING
Efavirenz 154598
Total flavonoids of Radix Tetrastigma suppress inflammation
Sonic hedgehog increases the commitment of pluripotent mesenchymal cells into the osteoblastic lineage and abolishes adipocytic differentiation PMID 11493644
Tetramethylpyrazine inhibits proliferation of colon cancer cells in vitro PMID 34222421
actin
Triptonoterpene Me ether
CRIg+ macrophages deficiency enhanced inflammation damage in IBD due to gut extracellular vesicles containing microbial DNA PMID 39024479
urothelial cancer
NOC 18
ASP 8497
Ethoxylated hydrogenated castor oil 61788
Cyclo(Phe
diadenosine polyphosphat
二苯环庚啶(Standard)
T
Glucose metabolite methylglyoxal induces vascular endothelial cell pyroptosis via NLRP3 inflammasome activation and oxidative stress in vitro and in vivo PMID 39269632
eIF
high
reoxygenation
Amyloglucosidase
5α
Ganoderma Lucidum/Reishi Extract
Acyltransferase
GSK2973980A
Cardiac fibroblast
L
Gasdermin D maintains bone mass by rewiring the endo
cis
2
entropy
relatively
Relacatib
reactivation
Mstn Mouse Pre
PDE3B
FGFR4
2′
Osimertinib (Standard) (AZD
1,N6
Synthesis and Biological Evaluation of NH2
布洛芬EP杂质P
ETC
hMDM2
Calophyllic acid 36626
OPC
CD37 分子(CD37)基因
FRS2 抗体 (YA1400)(FRS2 Antibody (YA1400))
Reverse Transcriptase
FGFR4 抗体 (YA1588)(FGFR4 Antibody (YA1588))
oxygen
Azalanstat
FGFR4 抗体 (YA4853)(FGFR4 Antibody (YA4853))
BLU9931
Hijacking of nucleotide biosynthesis and deamidation
Kinome reprogramming is a targetable vulnerability in ESR1 fusion
Different fusion tags affect the activity of ubiquitin overexpression on spastin protein stability PMID 34873900
Alteplase 105857
basic amine
MBD
Glyoxalase 1 inhibitor BBGC suppresses the progression of chronic lymphocytic leukemia and promotes the efficacy of Palbociclib PMID 36774689
Tissue
Epicochlioquinone A
(
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity PMID 35058574
Hsp110/sGC
6
CLM3
阿塞珠单抗
Large2 Mouse Pre
27128
RO 7049665
sFGFR3
PROTAC NAMPT Degrader
Glycodeoxycholic acid
CVS 738
Preliminary investigation of nitric oxide release from upconverted nanoparticles excited at 808 nm near
GPR119
The CRTC1
TelN Protelomerase
Radiotherapy Delivered before CDK4/6 Inhibitors Mediates Superior Therapeutic Effects in ER+ Breast Cancer PMID 33495311
miR
A Marine Alkaloid, Ascomylactam A, Suppresses Lung Tumorigenesis via Inducing Cell Cycle G1/S Arrest through ROS/Akt/Rb Pathway PMID 32992455
CRAC Channel
Cadmium inhibits apoptosis of human esophageal epithelial cells by upregulating CDK6 PMID 32827965
sFGFR
Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa PMID 15490316
EB1010
Disentangling Pro
sFGFR 3
Identification of predictors of drug sensitivity using patient
Potent anti
他替瑞林
Integrated genomic analyses in PDX model reveal a cyclin
Hexacosanoic acid methyl ester
Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells PMID 29330290
Dexmedetomidine alleviates acute lung injury by promoting Tregs differentiation via activation of AMPK/SIRT1 pathway PMID 36534240
The metabolic function of cyclin D3
KDM1A, a potent and selective target, for the treatment of DNMT3A
Cell
todo
p38 MAPK
NF
Dementia with Lewy bodies
FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted PMID 33887357
Preclinical assessment of MEK1/2 inhibitors for neurofibromatosis type 2
The protective role of RACK1 in hepatic ischemia‒reperfusion injury
5
DKK1 is epigenetically downregulated by promoter methylation and inhibits bile acid
Long
Candicine
α
Pim
Hemagglutinin Structure and Activities PMID 32513673
2
O
Pim kinases
proresolving mediator
PSMD14 promotes breast cancer progression by reducing K63
成纤维细胞活化蛋白α(FAP)基因
AZD1940
L
Imbalanced chromatin distribution in cellular senescence specifies paraspeckle dynamics PMID 40898359
AZD 7806
make
SIK
Asparamide
JNJ
Desmethyl nevanimibe
L
LY
JD02
IFN
KRT
TH5487, a small molecule inhibitor of OGG1, attenuates pulmonary fibrosis by NEDD4L
MK130
2,2',6
泊沙康唑
AZD6140
盐酸米诺环素 (标准品)
FOS
METTL7B Is Required for Cancer Cell Proliferation and Tumorigenesis in Non
Ethanol promotes alcohol
RAB38,RAS 致癌基因家族成员(RAB38)基因
AT
(S)
Attenuation of cardiac ischemia/reperfusion injury via the decoy receptor DcR2 by targeting the PLAD domain of the death receptor DR5 PMID 40154678
14
Early
5& 039;
UBCS 039
C3
HIV
C.I.颜料红48:2
pCREB
MNK/PIM
Civorebrutinib (WS
AP
Boc
CYP3A
Antitubercular agent
Metolachlor
LIM 同源框 1(LHX1)基因
Darusentan (Lu
1
去氟可特
Cy5
WAY100135
(N
LKB1
Astrocytic AT1R deficiency ameliorates Aβ
MB
Antimycin A2
NaPi2b
NIR
TNIK
MAT2A
MAGL
Cholesterol
LC3
7
SPP
Spicamycin
Cephapirin sodium 24356
Pyridate (Standard) (CL 11344 (Standard))
CDK1
tetrapyrrolic pigment
真核翻译起始因子 4E 家族成员 2(EIF4E2)基因
hsa
m6A
Broussonetia kanzinoki
Activation of BZW1 by CEBPB in macrophages promotes eIF2α phosphorylation
LL
M5 glycan (Man5), APTS labelled (Mannose
LUF5981
Dihydromyricetin resists inflammation
CMX410
IONIS
Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation PMID 38113886
LncRNA CASC19 promotes gastric cancer progression through preventing CREB1 protein ubiquitin/proteasome
RRLIEDAEpYAARG
FGFR
FGFR1 抗体 (YA6326)(FGFR1 Antibody (YA6326))
(Aminomethyl)phosphonic acid
antiserotonergic
Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds PMID 36599852
N
Astragaloside IV suppresses the migration and EMT progression of cervical cancer cells by inhibiting macrophage M2 polarization through TGFβ/Smad2/3 signaling PMID 37081108
Structure and function of vitamin K epoxide reductase PMID 18374192
A Study on Regulating OSCC Cell Function by Blocking Integrin αvβ3 With Cilengitide PMID 40589419
22
N
The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C
RO
Zwitterionic polymer modified xanthan gum with collagen II
hOR17
1
Activation of CaMKII+ neurons in the paramedian raphe nucleus promotes general anesthesia in male mice PMID 40360778
Additive Effect of CD73 Inhibitor in Colorectal Cancer Treatment With CDK4/6 Inhibitor Through Regulation of PD
The RBPJ/DAPK3/UBE3A signaling axis induces PBRM1 degradation to modulate the sensitivity of renal cell carcinoma to CDK4/6 inhibitors PMID 35368029
FBXO2 Promotes Proliferation of Endometrial Cancer by Ubiquitin
ABD 459
Functionalized Biomimetic Nanoparticles Targeting the IL
Bortezomib induces cell apoptosis and increases the efficacy of αPD
Fasting
Discovery and structure
rU Phosphoramidite
6
DBCO
LEM4 confers tamoxifen resistance to breast cancer cells by activating cyclin D
(5R)
ATPase
Formamide
Neuroplasticity
MK793
含约瑟芬域 1(JOSD1)基因
CETSA
1
Hepatoprotective effects of sevoflurane against hepatic ischemia
LncRNA NR_045147 modulates osteogenic differentiation and migration in PDLSCs via ITGB3BP degradation and mitochondrial dysfunction PMID 39674578
Clodronate A Vesicular ATP Release Blocker PMID 29146440
New perspectives on YTHDF2 O
Aladorian sodium 1233219
Isocytosine 108
dBAZ2
AMPK Promotes Larval Metamorphosis of Mytilus coruscus PMID 36553651
Antibiotic Azithromycin inhibits brown/beige fat functionality and promotes obesity in human and rodents PMID 35154482
Marine sponge
ALK
Thrombopoietin Mitigates Neuronal Death by Enhancing Mitophagy and Suppressing NLRP3 Inflammasome Activation Under Oxygen
CD31 regulates metastasis by inducing epithelial
Davoceticept (ALPN
尿嘧啶
Invariant natural killer T cells drive hepatic homeostasis in nonalcoholic fatty liver disease via sustained IL
Brefeldin A inhibits colorectal cancer growth by triggering Bip/Akt
3,4
Endoplasmic reticulum stress inhibits AR expression via the PERK/eIF2α/ATF4 pathway in luminal androgen receptor triple
Dabigatran
BIBR 953
Mitochondrial quality control protects photoreceptors against oxidative stress in the H2O2
Zinc
2
Identification of compounds targeting porcine reproductive and respiratory syndrome virus nsp3 and evaluation of their antiviral efficacy PMID 40619342
ALR2
S6K1 amplification confers innate resistance to CDK4/6 inhibitors through activating c
Tianeptine Metabolite MC5
Glycidyl stearate
Transient receptor potential vanilloid 4 (TRPV4) in neutrophils enhances myocardial ischemia/reperfusion injury PMID 37232941
iso
1
白介素 1 受体相关激酶 4(IRAK4)基因
MG
(Rac)
Sodium (±)
huHMFG 1
DL
FGFR
SMCy5.5
(R)
X
collagen
Defluoro linezolid
RAI3 knockdown enhances osteogenic differentiation of bone marrow mesenchymal stem cells via STAT3 signaling pathway PMID 32014253
Hypoxia reduces the osteogenic differentiation of peripheral blood mesenchymal stem cells by upregulating Notch
Mutant p53 achieves function by regulating EGR1 to induce epithelial mesenchymal transition PMID 39126833
Harnessing tissue
3
TOPBP1 as a potential predictive biomarker for enhanced combinatorial efficacy of olaparib and AZD6738 in PDAC PMID 39920847
Velloquercetin
SARS
PCR 5332
EphA2
Circular RNA cMras inhibits lung adenocarcinoma progression via modulating miR
CCT
Undecan
Flucycloxuron (Andalin)
Nucleolus assembly impairment leads to two
HER2/CD340 蛋白, Human (Biotinylated, Domain 4, HEK293, His
LYN
Formamide
Aldose reductase
Squalene protects against oxidative DNA damage in MCF10A human mammary epithelial cells but not in MCF7 and MDA
Single
Miquelianin inhibits IAV infection via the MAPK signaling pathway both in vitro and in vivo PMID 40165966
Deconvolution of calcium imaging data using marked point processes PMID 32163407
Long non
Simvastatin
ALZ
Human adipose and umbilical cord mesenchymal stem cell
(S,R,S)
ITGAM Human Pre
Phase 1 Studies of the Anti
Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats PMID 17229101
Methyltransferase
Pdgfb
2,2′
COP9 signalosome is an essential and druggable parasite target that regulates protein degradation PMID 32960936
Targeting STAT3 potentiates CDK4/6 inhibitors therapy in head and neck squamous cell carcinoma PMID 38735381
PMX
Synthesis and antitumor evaluation of 2,3
Chitinase
AMPTX
OCT4 accelerates tumorigenesis through activating JAK/STAT signaling in ovarian cancer side population cells PMID 30643464
HIV Integrase Inhibitor Pharmacogenetics An Exploratory Study PMID 30623371
regulated
Profiling of 3
2
Tetrahedral framework nucleic acid nanomaterials reduce the inflammatory damage in sepsis by inhibiting pyroptosis PMID 36802079
LIN28
Chronic stimulation desensitizes β2
Biotin
皮啡肽
Cyclo(Phe
RPL9 acts as an oncogene by shuttling miRNAs through exosomes in human hepatocellular carcinoma cells PMID 38639179
Klk13 Rat Pre
efficient fertilizer
USP5 deubiquitylates and stabilizes FcεRIγ to enhance IgE
3
Cell membrane
Volitional modulation of neuronal activity in the external globus pallidus by engagement of the cortical
4
Adrogolide
Boc
KIR2DL1 蛋白, Human (Biotinylated, HEK293, His
SGK1 contributes to ferroptosis in coronary heart disease through the NEDD4L/NF
5’
A phase I multidose study of dacetuzumab (SGN
Lupinalbin A
2
MHC
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influx PMID 33890549
Downregulation of PPARα mediates FABP1 expression, contributing to IgA nephropathy by stimulating ferroptosis in human mesangial cells PMID 36147466
Targeting X box
modulator
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