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生物活性分子最近更新
GR 250495X
补骨脂甲素
Role of excreted chlortetracycline in modifying the decomposition process in feedlot waste PMID 5153752
吗啉乙磺酸水合物
Nb
Tup
莴苣素
Stag1 Mouse Pre
Wnt16
Apicularen B
WEE1
EDA2R/XEDAR 蛋白, Mouse (HEK293, Fc)
1,3
(E/Z)
Cy2
digestion
Lennox
毛壳素
Antibacterial agent 212
Azido
CDC14A/B
5
STP1002
DAMGO
143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models PMID 36725884
罗替戈汀盐酸盐 (标准品)
5
Argyrin A
(Rac)
5
CP
FCV activates NLRP3 inflammasome through ion
BMS
Enhanced Store
Eprodisate disodium (NC
Sequosempervirin B
Apocynaceae
CDK7
Myristic anhydride
NSC 24874
Antitumor agent
Bcl
3,3′,4,5′
Lactate
Antidiabetic agent 2
阿斯巴甜 d<sub>3</sub>
氨萘非特 (Standard)
NSC 15520
加替沙星盐酸盐
PBP10
鲁卡帕尼磷酸盐 (Standard)
Deoxycholic acid
BDP 564/570 NHS ester
IWP4
Artemisitene
NSC 17764
Axitinib
ERα degrader
舒马曲坦
Dexamethasone impurity
Tiamenidine hydrochloride (HOE 440 hydrochloride)
WL 47 dimer
4
Mechanism of RBM15 in high glucose
Rusalatide
Kaposi's Sarcoma
Resolvin D
Colletotrichum acutatum
L
FGFRL1 蛋白, Human (HEK293, His)
MEDI2045
3,17β
Increased activation of cGAS
5α
β
Galangin induces the osteogenic differentiation of human amniotic mesenchymal stem cells via the JAK2/STAT3 signaling pathway PMID 36257381
The CCCH
AKT
L
FGFR
VE+822
DSPE
RB
NSC 756093
CaMKII autonomy is required for initiating but not for maintaining neuronal long
5
Matsupexolum
Phototoxicity
Tafenoquine Succinate (Standard) (他非诺喹琥珀酸盐 (Standard))
93
Inhibition of PI3 kinase isoform p110α suppresses neuroblastoma growth and induces the reduction of Anaplastic Lymphoma Kinase PMID 36585695
Hexokinase IV
Crip2 affects vascular development by fine
Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence PMID 28967919
2
oxidative tissue injury
c
布地奈德
Anti
4
3888
Ensitrelvir fumarate 2757470
Unveiling E2F4, TEAD1 and AP
Uniformly modified 2'
hnRNPA1 impedes snakehead vesiculovirus replication via competitively disrupting viral phosphoprotein
伐普肽
Snrpa Rat Pre
HCT
MAT2A
atherosclerosis
Emodin enhances host antiviral immunity against Micropterus salmoides rhabdovirus by activating RLR signaling in largemouth bass PMID 40769268
FGFRL1 蛋白, Mouse (HEK293, His)
20
Swiprosin
MRT
BCH 20448
Csnk2b
HIF
Acute and subchronic toxicity of pyraclostrobin in zebrafish (Danio rerio) PMID 28910725
芹菜素
Chromatographic fingerprint and the simultaneous determination of five bioactive components of geranium carolinianum L. water extract by high performance liquid chromatography PMID 22272101
Prallethrin (丙炔菊酯)
OX40/CD134
metastatic melanoma
Isobutylamido thiazolyl resorcinol
Dietary Supplement
NED
Pomonic acid
Citrullinated Aβ (1
SK 1404
HJC0149
H1568R
索马鲁肽三氟乙酸
FGF2
VUF
Indirubin
Lipid droplets participate in modulating innate immune genes in Ctenopharyngodon idella kidney cells PMID 30890432
Physiology of gastrin PMID 4893847
Notopterygium incisum extract (NRE) rescues cognitive deficits in APP/PS1 Alzhneimer's disease mice by attenuating amyloid
Chaetocin attenuates gout in mice through inhibiting HIF
Antibiofilm agent
Mat2a Mouse Pre
Oridonin Alleviates IRI
Iobitridol
Wy 48314
Osanetant
Favipiravir
pharmacokinetics
EML741
Kv
Dextran sulfate, high sulfate (MW 5000) (硫酸葡聚糖, 高硫酸盐 (MW 5000))
SNT
colon carcinoma
H
Dispersion indices for universal quantification of fluorescently
Amarogentin
TRIM21
MicroRNA
A
Atorvastatin (Standard)
chronic HBV infection
Precursor
Interaction of pyridinium bis
Gene and doxorubicin co
Cefoxitin (Standard)
3'
Geraniol
Untargeted metabolomic profiling identifies disease
AY
Foxgreen
Biotin
Isopropylaminoantipyrine
Ascorbyl tetra
Telotristat etiprate 1137608
1
STAT3
PRESSURE
A mouse protozoan boosts antigen
The co
Methyl
PLLA5000
Ki16425 (Standard)
利那拉生 (Standard)
Harzianopyridone
CDK4/6 Inhibitors Impede Chemoresistance and Inhibit Tumor Growth of Small Cell Lung Cancer PMID 39136283
OPSS
BAY Vq
The role of palbociclib on the alterations in CDKN2, CCNE1, E2F3, MDM2 expressions as target genes of miR
High Density Lipoproteins Metabolism, Function, and Therapeutic Potential PMID 32296714
Cuproptosis
Bacopaside I and II two pseudojujubogenin glycosides from Bacopa monniera PMID 11576596
Discovery of [1,2,4]triazolo[3,4
Discovery of CDK4 inhibitors by convolutional neural networks PMID 30556417
Anticancer agent 106 3009090
Myeloperoxidase inhibitor
Investigating the Effect of Tyrosine Kinase Inhibitors on the Interaction between Human Serum Albumin by Atomic Force Microscopy PMID 35740944
gastric cancer
Palmitic acid activates NLRP3 inflammasome through NF
Fructose
tuberculosis
Exogenous galanin alleviates hepatic steatosis by promoting autophagy via the AMPK
CRBN ligand
Empagliflozin attenuates the renal tubular ferroptosis in diabetic kidney disease through AMPK/NRF2 pathway PMID 36581059
Using Network Pharmacology for Systematic Understanding of Geniposide in Ameliorating Inflammatory Responses in Colitis Through Suppression of NLRP3 Inflammasome in Macrophage by AMPK/Sirt1 Dependent Signaling PMID 33202149
Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis PMID 15141377
Identification of disubstituted sulfonamide compounds as specific inhibitors of hepatitis B virus covalently closed circular DNA formation PMID 22644022
Amino acid sequence RERMS represents the active domain of amyloid beta/A4 protein precursor that promotes fibroblast growth PMID 8491779
HTL14242 (HTL0014242)
Overcoming Resistance to Targeted Anticancer Therapies through Small
Synthesis, anticancer activity, and iron affinity of the Actinoplanes metabolite 7,8
Ibrutinib selectively and irreversibly targets EGFR (L858R, Del19) mutant but is moderately resistant to EGFR (T790M) mutant NSCLC Cells PMID 26375053
Silybin
Targeting GPR84 to alleviate acute immune
primary chick embryo fibroblasts
N6
Anantin 133658
Temafloxacin 108319
α7 nACh receptor partial agonist
Inorganic arsenic exposure promotes malignant progression by HDAC6
A Novel Mechanism of Endoplasmic Reticulum Stress
M1 macrophage mediated increased reactive oxygen species (ROS) influence wound healing via the MAPK signaling in vitro and in vivo PMID 30690042
AZD 4205
Cyclobenzaprine
The Novel Application of EUK
Mitotic ER
Mitochondrial DNA leakage exacerbates odontoblast inflammation through gasdermin D
SNAC
Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes PMID 35614212
SYR
ovarian
Cytotoxicity of nitroheterocyclic compounds, quinifuryl and nitracrine, towards leukaemic and normal cells on the dark and under illumination with visible light PMID 15246347
Dehydrocholic acid (DHCA) substrate
BWX 46 (((Cys31, Nva 34)
cholesterol biosynthesis
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors PMID 18285474
Diclofenac sodium effectively inhibits the biofilm formation of Staphylococcus epidermidis PMID 38847838
18 0 Diether PC (1,2
HCV entry inhibitor
PHLPP
autophosphorylation
In Vivo and In Vitro Enhanced Tumoricidal Effects of Metformin, Active Vitamin D3, and 5
Xanthomonas oryzae pv oryzae
GSK
Two new naphthalenic lactone glycosides from Cassia obtusifolia L. seeds PMID 29948771
Effect of PEGylation on the Drug Release Performance and Hemocompatibility of Photoresponsive Drug
P53‑microRNA interactions regulate the response of colorectal tumor cells to oxaliplatin under normoxic and hypoxic conditions PMID 37921068
Role of l
金属硫蛋白 2A（MT2A）基因
α3 glycine receptors
Readers of poly(ADP
Aortic disease in Marfan syndrome is caused by overactivation of sGC
CSF1R
Involvement of VCP/UFD1/Nucleolin in the viral entry of Enterovirus A species PMID 32289342
HSP90
Guanylyl Imidodiphosphate trisodium 148892
Whole
modulator
Phleomycin 11006
Pax6 Mouse Pre
转录因子 19（TCF19）基因
Anti
NDUFB9 抗体 (YA1340)（NDUFB9 Antibody (YA1340)）
Bax 蛋白, Human (His)
Structure
AG 1295 71897
Cytotoxic dibromotyrosine
Irf3
2
BCM 599
Prostaglandin Bx (PGBx)
Large
Tryptamine guanosine carbamate (TpGc)
SMARCE1 Human Pre
LY 201409
D
Chlorozotocin 54749
Anticancer agent43
Fasudil Hydrochloride (Standard)
ATR kinase
sweetener
CXCR
rno
CXC chemokine receptors
C
SJ
2
AMPK a nutrient and energy sensor that maintains energy homeostasis PMID 22436748
Palmarumycin C3
Histrelin acetate 220810
Neuchromenin 180964
repair
Probucol inhibits ABCA1
胖乎乎的家族成员 2（CBY2）基因
Double
PF
A novel assay for screening WIP1 phosphatase substrates in nuclear extracts PMID 33982878
突触结合蛋白 2 结合蛋白（SYNJ2BP）基因
Imperatoxin A TFA
Antibody
2'
ByeTAC Bypassing E
Dephosphorylation of T517 on Hemocyanin Is Required for Antibacterial Activity in Penaeus vannamei PMID 36971684
4
Met抑制剂、降解剂、基因
A basophil
JC168
Senecionine acetate 126642
Acridone derivatives design, synthesis, and inhibition of breast cancer resistance protein ABCG2 PMID 17317193
AMPKα1 regulates Idh2 transcription through H2B O
GSK5182
2832
NBI31772
RIP2 Kinase Inhibitor 3
Co
Dynamic heterogeneity in an E. coli stress response regulon mediates gene activation and antimicrobial peptide tolerance PMID 39677761
Boc
1
SJB3
mmu
HIV Protease
tyrosine
Alginic acid/KLH
Immunomodulatory activity and molecular mechanisms of action of peptides derived from casein hydrolysate by alcalase and flavourzyme based on virtual screening PMID 39603497
GPR133 蛋白, Human (HEK293, His)
UBE2D3 Human Pre
3,7,8
CB
Dehydroepiandrosterone sulfate
Boc
Histamine H1 receptors in dentate gyrus
oxaloacetate
vitamin B6
LY6D 蛋白, Human (HEK293, Fc)
Mito Red 1021902
Synthesis of podophyllotoxin linked β
Sequence
Characterization of BRAFThr599dup Mutation as a Targetable Driver Mutation Identified in Lung Adenocarcinoma by Comprehensive Genomic Profiling PMID 38662982
Uridine and its nucleotides biological actions, therapeutic potentials PMID 10354618
Sarcandra glabra (Thunb.) Nakai relieves pain behavior by inhibiting NaV1.7 channels PMID 40412780
(R)
Vitexin
Molecular Mechanisms of Aminoglycoside
S
Differential responses of estrogen target tissues in rats including bone to clomiphene, enclomiphene, and zuclomiphene PMID 9724022
Bioactive components in prunella vulgaris for treating Hashimoto's disease via regulation of innate immune response in human thyrocytes PMID 39253271
liver
Aniline
Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat PMID 22803959
MRGPRX2 Mediates Mast Cell
U2 小核 RNA 辅助因子 1（U2AF1）基因
Mapk7 enhances osteogenesis and suppresses adipogenesis by activating Lrp6/β
Go6850
3
Tyrosine kinase inhibitors
泛素 C（UBC）基因
Kinase inhibitor
Epicochlioquinone A 147384
Interplay of drug transporters P
Anti
PF
Lysophosphatidic acid receptor 3 (LPAR3) regulates ocular surface chloride transport via calcium signaling PMID 40112945
SARS
Asb10 accelerates pathological cardiac remodeling by stabilizing HSP70 PMID 40399264
vacuolin
7
Sirtuin3 attenuates pressure overload
Dulcite
GAPDH 蛋白, Human (His
Targeting DNM1L/DRP1
Evaluation of the ability of carprofen and flunixin meglumine to inhibit activation of nuclear factor kappa B PMID 12602591
Bombiprenone (蚕沙酮)
Biotin
3ß
Aldehyde Dehydrogenase 2 Lactylation Aggravates Mitochondrial Dysfunction by Disrupting PHB2 Mediated Mitophagy in Acute Kidney Injury PMID 39737891
sideroflexin 1（SFXN1）基因
IL
Porcine reproductive and respiratory syndrome virus degrades TANK
The role of NMDA receptors in fish stress response Assessments based on physiology of the caudal neurosecretory system and defensive behavior PMID 39351903
Amlodipine benzenesulfonate
N
Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation PMID 38087889
索布瑞芙普α
A dual Keap1 and p47phox inhibitor Ginsenoside Rb1 ameliorates high glucose/ox
Peiminine triggers ferroptosis to inhibit breast cancer growth through triggering Nrf2 signaling PMID 38412577
PTBP3 Mediates IL
5
Chloride Channel/COX Inhibitor
Wnt signaling aberrant activation drives ameloblastoma invasion and recurrence bioinformatics and in vitro insights PMID 39574093
Monomeric and dimeric ent
盐酸罗哌卡因
Zfp36l1
Saframycin E 66082
Hydrocortisone buteprate (Hydrocortisone probutate)
pentose phosphate
Azelastine hydrochloride (Standard)
GPBAR1
β
Fmoc
D
Cletoquine
Ligand
Neuropeptide Y (human,rat,mouse) (Neuropeptide Y (29
替卡格雷
Cyclo(L
MK401
阿吗里新
20(S)
ML 471
B 701
莫能菌素
DMS
AC
Aspiculamycin
AMG 477
3,6
辛波莫德(Standard)
POL1
Cbz
pancreatic B cell
Dapsone and sulfones in dermatology overview and update PMID 11511841
Ganglioside GM2 mediates migration of tumor cells by interacting with integrin and modulating the downstream signaling pathway PMID 27066976
hsa
hsa
N
hsa
替卡格雷
An orally bioavailable broad
A
RETREG1
mmu
Glycogen synthase kinase
Azido
3,4
APN
Thalidomide
LDN
multiple
hsa
FGH 31
1,3,5,7
rheumatoid
VIR
hsa
UBP512
2
WDR5 抗体 (YA008)（WDR5 Antibody (YA008)）
MMP
HM43239
LG 82
Colorectal Cancer (CRC)
Anticancer agent3
SIRT2
Keap1
EN884
DYRK2 蛋白, Human (GST)
PI3K
FGF13 Human Pre
RBL
GST enzymes
Oleoylethanolamide
18 1 PE MCC
PSMA binder
TAN
YYA
High matrix stiffness promotes senescence of type II alveolar epithelial cells by lysosomal degradation of lamin A/C in pulmonary fibrosis PMID 40205454
quenched MMP peptide substrate
Human adenovirus type 7 (HAdV
Palmatine attenuates MYH9 mediated nuclear localization of AURKA to induce G2/M phase arrest in colorectal cancer cells PMID 39536490
CTL 002
Tumor
NGX 267
Inhibition of Histone Methyltransferase EZH2 Suppresses Endometriotic Vesicle Development in a Rat Model of Endometriosis PMID 32651901
Dronedarone hydrochloride (DH) induces pancreatic cancer cell death by triggering mtDNA
A small protein encoded by PCBP1
Selenoprotein W modulates tau homeostasis in an Alzheimer's disease mouse model PMID 39020075
BODIPY TR methyl ester
cPcAMP1/26
Mitophagy Regulates the Circadian Rhythms by Degrading NR1D1 in Simulated Microgravity and Isolation Environments PMID 38732079
IBI
Optogenetically engineered calcium oscillations promote autophagy
Porcine reproductive and respiratory syndrome virus 2 hijacks CMA
Anti
Lipoxin A4 analogue protects brain and reduces inflammation in a rat model of focal cerebral ischemia reperfusion PMID 20138164
Divergent sex
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis PMID 37831180
11
Homoplantaginin attenuates high glucose
FAAH served a key membrane
GSK1104252A
Pluracidomycin C3
Deregulation of Exo70 Facilitates Innate and Acquired Cisplatin Resistance in Epithelial Ovarian Cancer by Promoting Cisplatin Efflux PMID 34298686
Carnosine suppresses human glioma cells under normoxic and hypoxic conditions partly via inhibiting glutamine metabolism PMID 32782394
ARC1905
ZSH
BICP0 Negatively Regulates TRAF6
5F
self
Tumor Cell Slimming Regulates Tumor Progression through PLCL1/UCP1
胡萝卜甙
Gefitinib
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