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谷氨酰胺合成酶
Calpain Inhibitor VI (SJA6017)
MRGPRX1 agonist 3
Acteoside improves adipocyte browning by CDK6
Role for mitochondrial oxidants as regulators of cellular metabolism PMID 10982848
Foxb1 Rat Pre
Ginkgo biloba extract protects against diabetic cardiomyopathy by restoring autophagy via adenosine monophosphate
Bisphenol A interferes with lncRNA Fhadlos2 and RUNX3 association in adolescent mouse ovary PMID 37229876
Transcriptional control of a collagen deposition and adhesion process that promotes lung adenocarcinoma growth and metastasis PMID 34874914
HES5
角蛋白 16（KRT16）基因
Myocardin reverses insulin resistance and ameliorates cardiomyopathy by increasing IRS
Hyperoside promotes autophagy of colonic epithelial cells to protect intestinal barrier function in ulcerative colitis PMID 40525776
Navitoclax, a Bcl
ASP4000
Novel bioactive clerodane diterpenoids from the leaves and twigs of Casearia sylvestris PMID 11858737
Organoid
CBLB Regulates MAPK
LP17 (human) 887973
TUSC2 Human Pre
Lysophosphatidic acid
Influenza Virus
高芒果甙
Functional neuraminidase inhibitor resistance motifs in avian influenza A(H5Nx) viruses PMID 32750468
Protective effect of taraxasterol on acute lung injury induced by lipopolysaccharide in mice PMID 24548765
Polymeric Nanoparticles Controlled by On
Telisotuzumab 1781223
[SQUALENE PHYSIOLOGICAL AND PHARMACOLOGICAL PROPERTIES] PMID 26292512
Hemostatic Effect of 20(S)
DRAM1 plays a tumor suppressor role in NSCLC cells by promoting lysosomal degradation of EGFR PMID 32943616
MDM
Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway PMID 32627037
TRAP1 inhibits MIC60 ubiquitination to mitigate the injury of cardiomyocytes and protect mitochondria in extracellular acidosis PMID 34907169
Indole alkaloids from two cultured cyanobacteria, Westiellopsis sp. and Fischerella muscicola PMID 22863526
Honokiol alleviates ulcerative colitis by targeting PPAR
Development and evaluation of PLA based hybrid block copolymeric nanoparticles for systemic delivery of pirarubicin as an anti
Asebogenin Suppresses Thrombus Formation via Inhibition of Syk Phosphorylation PMID 36166754
Molecular Hydrogen Inhibits Colorectal Cancer Growth via the AKT/SCD1 Signaling Pathway PMID 35528164
Aminosalicylates target GPR35, partly contributing to the prevention of DSS
Discovery of PXR Antagonist MI891 and PXR Degrader MI1013 and Their Roles in Hepatic Gene Regulation PMID 40650588
Leptin excites basolateral amygdala principal neurons and reduces food intake by LepRb
A 1,10
Adgrf4 Rat Pre
(Rac)
E3 ligase RNF2 inhibits porcine circovirus type 3 replication by targeting its capsid protein for ubiquitination
PSMD12
forebrain neurons
AT511
intestinal permeability
5& 039;
Genetic variants (LhcgrW495X/+) and environmental toxicants (DEHP) synergistically induce DSD by interfering with steroidogenic gene expression PMID 41013757
Antitrypanosomal agent
hypouricemic effects
Targeted profiling of polar metabolites in cancer metabolic reprogramming by hydrophilic interaction liquid chromatography
Psoralidin induces pyroptosis in both tumor cells and macrophages as well as enhances nature killer cell cytotoxicity to suppress hepatocellular carcinoma PMID 40479862
3
Role of multi
<i>streptococci</i>
IR
D
Marine blue 84229
Down
Taraxasterol mediated autophagy inhibition in pancreatic encephalopathy involves its regulation on L1 cell adhesion molecule PMID 40051886
(S)
Dapagliflozin
L
Caylin
Identification of a new caspase homologue caspase
RAB8A，成员 RAS 致癌基因家族（RAB8A）基因
Methyl iodide
Syndecan
Modification of COL1A1 in Autologous Adipose Tissue
Ptprc
Tmub1 negatively regulates liver regeneration via inhibiting STAT3 phosphorylation PMID 30610893
Eurycomalactone 23062
NSC 319726
H4R3me2a
MiR
Tegaserod maleate exerts anti
DiO (solution)
Palmitoyl serinol (N
safety
Bag3 Mouse Pre
HCV
14β
5
Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice PMID 23721744
VHR phosphatase
Chloropolysporin B 105650
钙粘蛋白 17（CDH17）基因
DDTC
BZG 2
SARS
Antifolate
Magainin
Menaquinone K4
(3S)
Sodium iodoacetate
(1S,4S)
3,3'
CC 基序趋化因子受体 8（CCR8）基因
Ethyl
Concanavalin A
NFQ
Ctip2 抗体 (YA488)（Ctip2 Antibody (YA488)）
LEK 8841 methanesulfonate
Emitasvir
Single
Antiparasitic agent9
G
2'
PI3K/mTOR Inhibitor
Design, synthesis and pharmacological evaluation of multitarget GPR40 agonists/HDAC6 inhibitors for Alzheimer's disease PMID 40541115
Mitochondrial Calcium Uniporter
Targeting AKR1B1 inhibits metabolic reprogramming to reverse systemic therapy resistance in hepatocellular carcinoma PMID 40750772
Lactobacillus rhamnosus GG ameliorates triptolide
ESCRT III
Synthetic Retinoid Sulfarotene Selectively Inhibits Tumor
Porcine Epidemic Diarrhea Virus Infection of Porcine Intestinal Epithelial Cells Causes Mitochondrial DNA Release and the Activation of the NLRP3 Inflammasome to Mediate Interleukin
Perturbation of mammary epithelial cell apicobasal polarity by RHBDF1
N,N′
Caenorhabditis elegans
Dictamine (Standard) (Dictamnine (Standard)，白鲜碱 (Standard))
The Constituent
Accumulation of 8,9
Role of Microbial Metabolites of Histidine in the Development of Colitis PMID 35585003
Bexarotene protects against neurotoxicity partially through a PPARγ
Fructose
Inhibition of peroxisome
New role of the antidepressant imipramine as a Fascin1 inhibitor in colorectal cancer cells PMID 32080340
The cholesterol metabolite 25
Cortol
1
MYCN Human Pre
MAL2 reprograms lipid metabolism in intrahepatic cholangiocarcinoma via EGFR/SREBP
Mito
NSC 402921
Epigenetic
Defect of SLC38A3 promotes epithelial
SNX17 knockdown improves post
The glycolysis
L5178Y lymphoma
GR148672X 263890
DDIT3 aggravates TMJOA cartilage degradation via Nrf2/HO
Inhibition of metalloproteinases enhances the internalization of anti
AAP
Mogrol suppresses lung cancer cell growth by activating AMPK
1,3
Pentagastrin 5534
Fmoc
Ciliotherapy Remote Control of Primary Cilia Movement and Function by Magnetic Nanoparticles PMID 30860808
Drp1
ELA
4
Baicalein Induces Autophagy and Apoptosis through AMPK Pathway in Human Glioma Cells PMID 31488033
Aficamten 2364554
AVP Human Pre
NH
Anticancer agent 185
Large
hPBMC
Ethyl 4
Targeting Mechanics
Cd200r1l Mouse Pre
Modification of 7
ASP
Acetaminophen
cBu
(R)
索密痛
AMPK impairment caused by gelatin disturbs mitochondrial dynamics leading to enhanced phagocytosis of bacteria in PMA
RHEB 蛋白, Human (GST)
AMPK activator 7
HN 2210
Amplification of CDK4 and MDM2 a detailed study of a high
Omipalisib inspired macrocycles as dual PI3K/mTOR inhibitors PMID 33360802
Vitexin 4'
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity PMID 36445063
Valine acts as an early biomarker and exacerbates pathological cardiac hypertrophy by impairing mitochondrial quality control PMID 40318256
Structure
Stanniocalcin2 inhibits the epithelial
OX40/TNFRSF4 蛋白, Human (Biotinylated, HEK293, His
Evaluation of the Apoptotic, Prooxidative and Therapeutic Effects of Odoroside A on Lung Cancer An In Vitro Study Extended with In Silico Analyses of Human Lung Cancer Datasets PMID 40141789
早期生长反应 4（EGR4）基因
ATAXIA TELANGIECTASIA MUTATED PROTECTS AGAINST LIPOPOLYSACCARIDE
Kynurenine acts as a signaling molecule to attenuate pulmonary fibrosis by enhancing the AHR
xenograft mouse tumor models
Azide
CaMK
2
In Vitro Synergy Testing of Eravacycline in Combination with Clarithromycin and Rifabutin against Mycobacterium abscessus Complex PMID 34132613
Aldometanib mitigates LPS
Anti
Investigating the potential role of EIF2S2 in OSCC progression through comprehensive bioinformatics analysis and experimental validation PMID 40605071
Virus
VS 6063
GMP FLT3LG 蛋白, Human (HEK293, His)
Analgesic effect
Propargyl
SGC agonist 2
MCE
H
Exercise alleviates hematopoietic stem cell injury following radiation via the carnosine/Slc15a2
MK2
G9a
TA
Protocol for differentiation of human embryonic stem cells into surface epithelium and functional keratinocytes PMID 40580474
Pdcd10
Efimosfermin alfa
T cell costimulus
Microglial forkhead box O3a deficiency attenuates LPS
Maximin S4
Toll
DS 7423
Development of a novel antibody to calcitonin gene
Multinoside A
Elabela ameliorates doxorubicin
FOOD
Polyketomycin 200625
Differential effects of Huaier aqueous extract on human CD4+T lymphocytes from patients with primary immune thrombocytopenia PMID 34450221
Sirtuin
The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet
Peptide
Molecular characterization of MSX2 gene and its role in regulating steroidogenesis in yak (Bos grunniens) cumulus granulosa cells PMID 39427591
Resolvin D1 Improves the Resolution of Inflammation via Activating NF
W 3699 (Probilin)
CD40 蛋白, Canine (HEK293, Fc)
Chlorzoxazone Alleviates Experimental Autoimmune Encephalomyelitis via Inhibiting IL
Clascoterone 19608
Transcriptomic Analysis Revealed an Important Role of Peroxisome
Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription PMID 35081346
Midaglizole
Discovery of 2
P053 2748196
Nannocystin ax, an eEF1A inhibitor, induces G1 cell cycle arrest and caspase
patZ 蛋白, E.coli
Computer
African swine fever virus enhances viral replication by increasing intracellular reduced glutathione levels, which suppresses stress granule formation PMID 39707514
Suppression of A
Involvement of TMAO in exacerbating arsenic
Bendamustine
CCL3 participates in the development of rheumatoid arthritis by activating AKT PMID 30402834
2
Hydroxyterbuthylazinel
Calcineurin/NFATc3 pathway mediates myocardial fibrosis in diabetes by impairing enhancer of zeste homolog 2 of cardiac fibroblasts PMID 37735624
6
depletion
Bu Shen Huo Xue Formula Provides Neuroprotection Against Spinal Cord Injury by Inhibiting Oxidative Stress by Activating the Nrf2 Signaling Pathway PMID 39494153
CRTh2 antagonist 4
Mephenesin
氨甲叶酸 (Standard)
Tau
Silencing c
FITC
Downregulation of fascin in the first trimester placental villi is associated with early recurrent miscarriage PMID 33862100
Preactivated PE
3,5
Pyruvic acid (Standard)
CAL51 cells
Ccn4
Discovery of novel BCR
The interferon regulatory factor 6 promotes cisplatin sensitivity in colorectal cancer PMID 35443865
CD79 蛋白, Human (HEK293, Flag
mmu
ERK
Effect of allyl isothiocyanate on oxidative stress in COPD via the AhR / CYP1A1 and Nrf2 / NQO1 pathways and the underlying mechanism PMID 36996530
血管动蛋白样 2（AMOTL2）基因
Arctiin, a lignan compound, enhances adipose tissue browning and energy expenditure by activating the adenosine A2A receptor PMID 40369420
Direct Red 75 tetrasodium
Autophagy inducer6
HS56
2
Calmodulin antagonist 1
T
NSC 680410
VEGFR
17
Yanghe Decoction promotes ferroptosis through PPARγ
2
TNFRSF1A Human Pre
RAD23 同系物 B，核苷酸切除修复蛋白（RAD23B）基因
Pretreatment with Panaxatriol Saponin Attenuates Mitochondrial Apoptosis and Oxidative Stress to Facilitate Treatment of Myocardial Ischemia
A13 B7
KIR3DL3/CD158z 蛋白, Human (Biotinylated, HEK293, His
1
Structure
RNF157 targets RIG
REGN7257
LncRNA446 Regulates Tight Junctions by Inhibiting the Ubiquitinated Degradation of Alix after Porcine Epidemic Diarrhea Virus Infection PMID 36790206
Pomalidomide
CD30 Ligand/TNFSF8 蛋白, Human (HEK293, N
Identification of a ferroptosis
MJ210
Penicillin G
preclinical
Anti
MC
PGK1 蛋白, Human (HEK293, His)
FPPS inhibitor
苯唑西林钠一水合物
转谷氨酰胺酶 1（TGM1）基因
Eastman7851
Boc
RAF709
吡啶类化合物 (Pyridine Alkaloids)
LDC3140
ML 083
M 3913
细胞间粘附分子 5（ICAM5）基因
Ala
Triacetyl
EGCG Restricts PRRSV Proliferation by Disturbing Lipid Metabolism PMID 35404086
Lanostane triterpenoids from Ganoderma calidophilum exhibit potent anti
NCAM
Benzethonium
Cellulase inhibits Burkholderia cepacia biofilms on diverse prosthetic materials PMID 24459841
Hormonally upregulated neu tumor
双特异性磷酸酶 14 (Dual Specificity Protein Phosphatase 14 (DUSP14))
Geraniin 60976
BU 08028
sEVsRVG selectively delivers antiviral siRNA to fetus brain, inhibits ZIKV infection and mitigates ZIKV
毛花强心丙(Standard)
PTPRC/CD45RAB 蛋白, Human (HEK293, His)
hydroxy
N
KR
HDAC6
Gene
Biotin
Carboxytolbutamide
Characterizing the Neuron
TEX37 Human Pre
J22352
5'
Structure and regulation of the myotonic dystrophy kinase
Yi
cholinergic pathway
3
CDK4/6
Flunisolide acetate
CH5015765
Ethyl 3
Radix Astragali
Oroxylin A reverses SHP
Bleximenib, the novel menin
[Tyr6]
PROTAC Linker 15
FLT3LG
Climbazole
Galectin
In Vitro Modeling of Recurrent Dermatofibrosarcoma Protuberans Assessment of 5
Dihydridotetrakis(triphenylphosphine)ruthenium(II) (Tetrakis(triphenylphosphine)ruthenium dihydride，二氢四(三苯基膦)钌)
Leukotriene D4
Pyridoxol
7
6
aminoglycosides
Chick CB8 of type II collagen (Chick cyanogen bromide digested peptide 8)
Chromogranin A 抗体 (YA5678)（Chromogranin A Antibody (YA5678)）
CTAB
Metformin ameliorates calcium oxalate crystallization and stone formation by activating the Nrf2/HO
budding
Assembly and cooperative mechanism of the hexameric fungal plasma membrane H+
Nintedanib impurity7
Paeoniflorin attenuates chronic constriction injury
KIN59 (5'
30 S ribosomal subunit
SIRT6 knockdown alleviates keratinocyte hyperproliferation and inflammation in psoriasis via modulating acetylation of FOXO1 PMID 39733643
CML
cytarabine
cardiac muscle
Propyl n
IDH1 Inhibitor 7
Curcumin Inhibits Lipopolysaccharide
AZ
(1S,3R)
Grosvenorine (罗汉果黄素)
low cell cytotoxicity
YAN, a novel microtubule inhibitor, inhibits P
BAY
Polymeric dual
MiR
伊潘立酮 d&lt;sub&gt;3&lt;/sub&gt;
CpG ODN activates NO and iNOS production in mouse macrophage cell line (RAW 264.7) PMID 12067301
NFYA Human Pre
蛋白磷酸酶 1 调节亚基 13B（PPP1R13B）基因
Oxygen
Teprasiran
磷酸西他列汀一水合物 (Standard)
Diogenes reagent
Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors PMID 11750180
Target Protein Ligand
Kinetics of RTK activation determine ERK reactivation and resistance to dual BRAF/MEK inhibition in melanoma PMID 37252843
6PGD
MCE
Manumycin G 156250
U18666A
PCB 118
Ginkgolic acids inhibit SARS
CASP9 Human Pre
8
Propanoic
ZD 9238
普鲁兰酶
Benzopyrimidin
Fura PE
MR837
Melatonin ameliorates renal fibroblast
4
DMT
mutant
Chronic Stress
Pentaerythritol dibromide
High dietary fructose promotes hepatocellular carcinoma progression by enhancing O
AVP Human Pre
Mechanical Activation of cPLA2 Impedes Fatty Acid β
Protective effects of melatonin on DEHP
ABCC6 Human Pre
M17
A pomalidomide
YCH1899
BCL6
Hypoxia exposure impairs male fertility via inhibiting Septin2
Capan
含 FERM 域 7（FRMD7）基因
The resveratrol attenuates reactive oxygen species mediated DNA damage in cardiac malformations caused by 4
4
CD200 Human Pre
Gossypin (Standard)
PARP8 Human Pre
Spontaneous Crimping of Gelatin Methacryloyl Nanofibrils Induced by Limited Hydration PMID 40679322
N,N,N
敌百虫
4
STING
3
Tianqi Yizhi Granule alleviates cognitive dysfunction and neurodegeneration in SAMP8 mice via the PKC/ERK pathway PMID 39986222
EIF2B5 Human Pre
Tirofiban hydrochloride 142373
Paracetamol
Nsun2 coupling with RoRγt shapes the fate of Th17 cells and promotes colitis PMID 36792629
Mucidin 52110
Isopropyl L
Forchlorfenuron
5
SHMT2 promotes tumor growth through VEGF and MAPK signaling pathway in breast cancer PMID 35968337
MCF7
MCE
Olivomycin A 6988
Picrasma quassioides Extract Elevates the Cervical Cancer Cell Apoptosis Through ROS
Monotropitin
Cd63
戊烷脒二盐酸盐
JNJ54861911
MLCK抑制剂、基因
Ala
AMP
PF
1,2
Neoruscogenin
DL
Ctsc Rat Pre
塞福太
TAS
OSI
喹啉酸 d<sub>3</sub>
Fmoc
Hydroxytolbutamide
Corymbol 7047
Lupulone
Obovatol
TNPO2 Human Pre
1,2
HT
Iclaprim (AR
Mechanism of KDM4A in Regulating Microglial Polarization in Ischemic Stroke PMID 40080374
and colitis
Bombyx mandarina
Etimizol (Ethimizole)
Snrpg Rat Pre
Ostenol
Antibacterial agent 252 hydrochloride
MCE
Downregulation of RIG
3,3'
HEK293 cells
Ginsenoside Rg1 regulating inflammatory response and bone
ACBI 4
hsa
sn
Leukotriene D4
Repurposing pinaverium bromide against Staphylococcus and its biofilms with new mechanisms PMID 39718732
Dihydridotetrakis(triphenylphosphine)ruthenium(II)
Fmoc
oxygen
Z
BMMSCs
HA9104
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