最近收录_第564页_生物活性分子
生物活性分子最近更新
Omipalisib 1086062
3
Inhibition of γ
4,6
Dysf Rat Pre
酶和蛋白标记二抗 (Enzyme and Protein Conjugated Secondary Antibodies)
Diquafosol tetrasodium 211427
Low levels of pyruvate induced by a positive feedback loop protects cholangiocarcinoma cells from apoptosis PMID 30866966
Diclofenac acyl glucuronide (D
Glutathione oxidized (Standard)
Anti
Advanced oxidation protein products upregulate efflux transporter expression and activity through activation of the Nrf
TRIM25 inhibits infectious bursal disease virus replication by targeting VP3 for ubiquitination and degradation PMID 34516573
Small
ERD
High
Matrilin
RPC
BP766 (Standard)
EGIS
Licorice zinc suppresses melanogenesis via inhibiting the activation of P38MAPK and JNK signaling pathway in C57BL/6J mice skin PMID 36542040
high durability
FGF2 promotes the proliferation of injured granulosa cells in premature ovarian failure via Hippo
RB
THR
Low
D
Desmonomethylpromazine
XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence PMID 31216022
Desmonomethylpromazine 2095
Development of Nurr1 agonists from amodiaquine by scaffold hopping and fragment growing PMID 38951694
Insight into the role of mitochondrion
Photobinding of some 7
Determination of desmethyl nortriptyline in plasma by gas chromatography before and after treatment with salicylaldehyde PMID 6874839
Costunolide ameliorates colitis via specific inhibition of HIF1α/glycolysis
Analyzing the role of cannabinoids as modulators of Wnt/β
Berberine mitigates high glucose
The promising antioxidant effects of lignans Nrf2 activation comes into view PMID 38695909
3,3'
Essential fatty acids in perspective PMID 6469703
SKF
Pentaerythritol tetra(3
LY2371712
Neriifolin 466
心脏疾病 (Heart Disease)
PSI
Troponin T3 ameliorates sepsis
A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways PMID 30082823
Xanthine (黄嘌呤)
Carboxypeptidase A2/CPA2 蛋白, Rat (HEK293, His)
Polyproline
1,2
RPR107393
HSD17B13
散乱片段极性蛋白 3（DVL3）基因
LncRNA TDRG1 promotes the proliferation, migration, and invasion of cervical cancer cells by sponging miR
5
Paris saponin VII 68124
Matrix metalloproteinase 3 (MMP
Strategies for the Activation and Release of the Membranolytic Peptide Melittin from Liposomes Using Endosomal pH as a Trigger PMID 28004569
Cgp 38560 methanesulfonate
3
FITC
The Novel Curcumin Derivative 1g Induces Mitochondrial and ER
Targeted delivery of diverse biomolecules with engineered bacterial nanosyringes PMID 40796978
Fidarestat 136087
RDN2150
NCK 衔接蛋白 2（NCK2）基因
Erythropoietin (EPO) Alleviates Chronic Stress
MCE
YKL
Anoctamin 5 promotes osteosarcoma development by increasing degradation of Nel
OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1 PMID 38658981
K9321
In vitro reconstitution of the hormone
Comprehensive analysis identifies ubiquitin ligase FBXO42 as a tumor
2'
Inhibition of CDGSH iron‑sulfur domain 2 exhibits tumor
自身免疫性疾病 (Autoimmune Disease)
PROX1 is an early driver of lineage plasticity in prostate cancer PMID 40454483
2,5
The role of Ephexin1 in translation and mTOR
Efanesoctocog alfa (BIVV
Rapid and dynamic detection of endogenous proteins through in
Phage protein Gp11 blocks Staphylococcus aureus cell division by inhibiting peptidoglycan biosynthesis PMID 38752726
R
Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium PMID 12414636
AZD
OGG1 蛋白, Human (N
Cytokine release syndrome in severe COVID
DNA Stain
rno
Porous COS@SiO2 Nanocomposites Ameliorate Severe Acute Pancreatitis and Associated Lung Injury by Regulating the Nrf2 Signaling Pathway in Mice PMID 33134248
Taurolithocholic Acid
Decitabine regulates the resistance of HCC to sorafenib through demethylation PMID 40624511
IodoFinder Machine Learning
Na+/H+ Exchanger Regulates Amino Acid
CD146/MCAM 蛋白, Human (HEK293, Fc)
Acetyl
Morf4 家族相关蛋白 1（MRFAP1）基因
1
Helicobacter pylori CagA promotes gastric cancer immune escape by upregulating SQLE PMID 39809787
4
The Mechanism of Ca(2+) Movement in the Involvement of Baicalein
A deep insight into the transcriptome of midgut and fat body reveals the toxic mechanism of fluoride exposure in silkworm PMID 32799150
Pro
HI
(
PDIA3 蛋白, Human (HEK293, His)
MIEN1 on the 17q12 amplicon facilitates the malignant behaviors of gastric cancer via activating IL
Antiproliferative activity of the ellagic acid
Trans
Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone
Myristelaidic acid (trans
Immune mechanisms shape the clonal landscape during early progression of prostate cancer PMID 37148881
Ginsenoside Rc 11021
Lamprey immune protein triggers the ferroptosis pathway during zebrafish embryonic development PMID 35978430
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase PMID 25197057
Genetically prolonged beige fat in male mice confers long
4
substance
Lactylation stabilizes TFEB to elevate autophagy and lysosomal activity PMID 39196068
Peroxisome proliferator
Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor PMID 15075359
AA26
CABP
[Leu15]
LP
BMS345541
层粘连蛋白
5
2,6
Glycidyl eicosapentaenoate
Ageladine A dihydrochloride 2757574
CAS No. 540796
Clemizole hydrochloride 1163
ACSL4 promotes hepatocellular carcinoma progression via c
?Eimeria meleagrimitis
Cucurbitacin IIb exhibits anti
Modulation of lipid profile by secretory phospholipase A2 group IIA Verification with a transgenic mouse model PMID 38640737
胞磷胆碱 (Standard)
Phosphorylated NFS1 weakens oxaliplatin
W 3699 17243
Cue
BocNH
Ibudilast 50847
RNA
β
SCL
PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation PMID 40281343
C1qa
FGF
KDM6A promotes imatinib resistance through YY1
LINC MIR503HG Controls SC
The slow and long
Mechanisms of LncRNA FTX in Regulating Islet Function of Pregnant Mice Born With Low
Direct blue 218 28407
Norethindrone Acetate
Chloranthus
Defective autophagy contributes to bupivacaine
Triple
Anti
Soluble epoxide hydrolase inhibitor (TPPU) alleviates ferroptosis by regulating CCL5 after intracerebral hemorrhage in mice PMID 38377737
Fenoxycarb (Standard)
Zifcasiran sodium (ADS
A20 attenuates oxidized self
Valpromide 2430
Y02224
Linc00941 fuels ribogenesis and protein synthesis by supporting robust cMYC translation in malignant pleural mesothelioma PMID 38729555
A novel L
Cdc5l Mouse Pre
MPSD control peptide 190711
Gallic Acid Ameliorates Aspergillus Fumigatus Keratitis Through Reducing Fungal Load and Suppressing the Inflammatory Response PMID 36350620
卵叶胡椒提取物 (Piper attenuatum Buch.
Response of a simian immunodeficiency virus (SIVmac251) to raltegravir a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy PMID 20233398
Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia PMID 22829080
Serotonin
Lactate triggers KAT8
动力 1（DNM1）基因
(3R,5S)
Securinine from Phyllanthus glaucus Induces Cell Cycle Arrest and Apoptosis in Human Cervical Cancer HeLa Cells PMID 27792748
Disorder of Iron Metabolism Inhibits the Recovery of Unloading
Transfer toxicity of polystyrene microplastics in vivo Multi
Fluorofenidone
Elaidic acid (反油酸)
Antifungal agent 44
ARIH1 inhibits influenza A virus replication and facilitates RIG
发芽的 RTK 信号拮抗因子 1（SPRY1）基因
Stabilization of Hypoxia
Repurposing anti
Macrophage
A transcriptomic analysis of the effects of macrophage polarization and endotoxin tolerance on the response to Salmonella PMID 36240188
Broad
Pregnane X Receptor (PXR)
m6A modification of lncRNA ABHD11
EpCAM/TROP1 蛋白, Human (Biotinylated, HEK293, Fc
2'
散乱片段极性蛋白 2（DVL2）基因
PTEN
Camptothecin derivative
653
Copper mediated follicular atresia Implications for granulosa cell death PMID 39106724
BRD7 suppresses tumor chemosensitivity to CHK1 inhibitors by inhibiting USP1
(±)
2
Dopamine
O
Drp1
TRBC1
Inhibition of growth of experimental prostate cancer in rats by LH
Cyclo(Arg
HMGB
盐酸去氧肾上腺素 (Standard)
USP25 inhibition ameliorates Alzheimer's pathology through the regulation of APP processing and Aβ generation PMID 35229730
舒噻美
Klotho ameliorates angiotension
Structural characterization of polysaccharides with potential antioxidant and immunomodulatory activities from Chinese water chestnut peels PMID 32747236
ZnO@Cu5.4O Nanoparticle Alleviates Inflammatory Responses of Intestinal Epithelial Cells by Inhibiting the Expression of GSDMB PMID 40521506
Methyl 3
转化生长因子β2（TGFB2）基因
Quercetin Nanoparticle Ameliorates Lipopolysaccharide
CAPN1 蛋白, Human (His)
Ginsenoside Rb1 Alleviated High
hsa
(Z)
A high
Lactylated Apolipoprotein C
bilateral olfactory bulbectomy
Petadeferitrin
Afatinib amplifies cAMP
Structural Modification of Natural Product Tanshinone I Leading to Discovery of Novel Nitrogen
2,5
t
IL
Ebribafusp alfa
The clinical KRAS(G12C) inhibitor AMG 510 drives anti
胱抑素 B（CSTB）基因
Stromelysin 1
Baricitinib
O
丙酸维生素A
Stromelysin1
Trichinella spiralis Paramyosin Alleviates Collagen
Lauryl benzalkonium chloride 139
EpCAM/TROP1 蛋白, Rhesus Macaque (HEK293)
刺五加甙E (Standard)
W
Naringenin ameliorates insulin resistance by modulating endoplasmic reticulum stress in hepatitis C virus
Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F
Identification and Characterization of the First Selective Y4 Receptor Positive Allosteric Modulator PMID 28795803
Combining radiation and the ATR inhibitor berzosertib activates STING signaling and enhances immunotherapy via inhibiting SHP1 function in colorectal cancer PMID 36855844
N
Long noncoding RNA SNHG7 inhibits high glucose
Lignoceric acid
FTY720 induces non
5
Norboldine improves cognitive impairment and pathological features in Alzheimer's disease by activating AMPK/GSK3β/Nrf2 signaling pathway PMID 38944357
In vitro test battery for testing molecular initiating events in chemical
Autophagy
2
氯沙坦钾
GSK
BRD
Darovasertib (LXS196)
β
2,3,3′,4,5,5′
1
ICEC0942 hydrochloride dihydrate
acetylcholinesterse
Dipropargyl substituted diphenylpyrimidines as dual inhibitors of monoamine oxidase and acetylcholinesterase PMID 31151057
SOS1
Intracellularly Synthesized Artificial Exosome Treats Acute Lung Injury PMID 39087239
Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Protect Liver Ischemia/Reperfusion Injury by Reducing CD154 Expression on CD4+ T Cells via CCT2 PMID 32999825
Pyridoxylamine
KGF/FGF
Poor performing rats
Synthesis and antitumor activities of naturally occurring oleanolic acid triterpenoid saponins and their derivatives PMID 23639650
2,3
ROC
red
Idebenone 58186
TXNIP exacerbates the senescence and ageing
GPNMB disrupts SNARE complex assembly to maintain bacterial proliferation within macrophages PMID 40038549
Locations of antibody binding sites within conserved regions of the hepatitis C virus core protein PMID 7521899
ESI
NPC 15199
Fmoc
combined salt
TRPM8 overexpression suppresses hepatocellular carcinoma progression and improves survival by modulating the RTP3/STAT3 pathway PMID 39385506
Neuronal Damage Induced by Gradual Oxidative Stress in iPSC
Vertilmicin sulfate
Bofutrelvir (FB2001)
Nitroparacetamol (NCX
Glutamic acid
4
KDX1381
Zibrofusidic acid (24
Efpixileukin alfa (XENP
Flumizole
MicroRNA
Estradiol dipropionate
Staphyloferrin A
A novel 2.5D culture platform to investigate the role of stiffness gradients on adhesion
Tioxacin
L
3
1,2
KDX 1381
Fmoc
Ceritinib
Fmoc
TRIM50 Inhibits Proliferation and Metastasis of Gastric Cancer via Promoting β
BRX 005
IL
Antiviral effect of vesatolimod (GS
IL
Cathelicidin Antimicrobial Peptide LL37 Induces TLR8 and Amplifies IL
Apocynoside I 358721
OPRD1 Human Pre
CXCL4 deficiency limits M4 macrophage infiltration and attenuates hyperoxia
Bovine Serum Albumin Nanoparticle
The circular RNA ciRS
5
PPM1D activity promotes the replication stress caused by cyclin E1 overexpression PMID 37067201
5
unc
Efficient engulfment of necroptotic and pyroptotic cells by nonprofessional and professional phagocytes PMID 31632688
Synthesis and evaluation of a ring
Cholecystokinin Receptor
Cordycepin Modulates Body Weight by Reducing Prolactin Via an Adenosine A1 Receptor PMID 30124145
Sevoflurane exposure accelerates the onset of cognitive impairment via promoting p
N
Fucosylated chondroitin sulfate exerts in vitro anti
Methyl 3
Endogenous GDF11 regulates odontogenic differentiation of dental pulp stem cells PMID 32845070
Olaratumab 1024603
CXCR
Synthesis and in vitro antitumor evaluation of betulin acid ester derivatives as novel apoptosis inducers PMID 26280921
NVP
Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF
N1,N1,N3,N3
Sphingosine
PoxB
MicroRNA
Carboxypeptidase B2/CPB2 蛋白, Rat (HEK293, His)
sulfonylurea class
Overcoming Non
Anesthesia/surgery activate MMP9 leading to blood
PS48 1180676
Platelet secretion induced by phorbol esters stimulation is mediated through phosphorylation of MARCKS a MARCKS
Apo
Discovery of Rapid
Radionuclide
GDC
Adipocyte RNA
Lymecycline (Mucomycin)
Tranylcypromine and 6
CD71 is selectively and ubiquitously expressed at high levels in erythroid precursors of all maturation stages a comparative immunochemical study with glycophorin A and hemoglobin A PMID 21415701
ATV2301
Damnacanthus giganteus extract block diffuse large b
Sodium 2
Pharmacological control of platelet
Differential effect of alpha
AG 538
Fibroblast growth factor 18 exerts anti
C32 0 FAME
(
Therapeutic Targeting PLK1 by ON
心力衰竭 (Heart Failure)
二磷酸普奈马奎
Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal PMID 36333323
Retinoic acid signalling inhibits myogenesis by blocking MYOD translation in pig skeletal muscle cells PMID 38753962
TSPAN32 suppresses chronic myeloid leukemia pathogenesis and progression by stabilizing PTEN PMID 36854750
Dynole 2−24 1416313
hypocalcemia
TP53AIP1 induce autophagy via the AKT/mTOR signaling pathway in the breast cancer cells PMID 39223776
YAP ISGylation increases its stability and promotes its positive regulation on PPP by stimulating 6PGL transcription PMID 35149670
Quercetin promotes autophagy to alleviate cigarette smoke
Inhibition of 12/15
PKI 14
CDC5L Human Pre
Tbx19 Mouse Pre
Rip2 Is Required for Nod2
GSK
MicroRNA
Aminometradine 642
NH
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML PMID 40057764
ML385 846557
ATP 结合盒亚家族 C 成员 2（ABCC2）基因
Targeting CXCL16 and STAT1 augments immune checkpoint blockade therapy in triple
CircRNA GRAMD4 induces NBR1 expression to promote autophagy and immune escape in renal cell carcinoma PMID 40373256
Synthesis and antiprotozoal activities of simplified analogs of naphthylisoquinoline alkaloids PMID 17475370
lysosome
para
Dcx
Spatial distribution of IL4 controls iNKT cell
Hydroquinine Inhibits the Growth of Multidrug
Ferroptosis Inducers in Thyroid Cancer PMID 36195678
VEGF
Intracellular delivery of 10
WNK1 Kinase Stimulates Angiogenesis to Promote Tumor Growth and Metastasis PMID 32131390
LG 82
Enteric coronavirus PDCoV evokes a non
Acetylcholine acts through M3 muscarinic receptor to activate the EGFR signaling and promotes gastric cancer cell proliferation PMID 28102288
Imperatorin induces autophagy and G0/G1 phase arrest via PTEN
Pharmacological characterization of GPR55, a putative cannabinoid receptor PMID 20298715
VHL Ligand
Norlaudanosoline
KLF5 Human Pre
1,2,3
NDRG1 facilitates self
Diclofenac deanol
LCI 699
CRISPR Dependency Screens in Primary Hematopoietic Stem Cells Identify KDM3B as a Genotype Specific Vulnerability in IDH2
MG 149 1243583
Intrinsic Xenobiotic Resistance of the Intestinal Stem Cell Niche PMID 30146480
Photosensitizer
TRPA1 deficiency aggravates dilated cardiomyopathy by promoting S100A8 expression to induce M1 macrophage polarization in rats PMID 37219522
Δ4
n
Comparative study of the effect of 17 parabens on PXR
PJA1 Coordinates with the SMC5/6 Complex To Restrict DNA Viruses and Episomal Genes in an Interferon
Cirsiliol induces autophagy and mitochondrial apoptosis through the AKT/FOXO1 axis and influences methotrexate resistance in osteosarcoma PMID 38087310
Cell
Lysine
3,5
Neuroprotective potential of nuclear factor erythroid 2
Imidazoleacetic acid hydrochloride (Standard)
Biotin
SKF
CD19 蛋白, Human (Biotinylated, HEK293, Fc
Structural proof of a dimeric positive modulator bridging two identical AMPA receptor
[D
Functional analysis of a novel positive allosteric modulator of AMPA receptors derived from a structure
(S)
Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin PMID 11085529
Oct4 inducer
ATP13A1 engages SEC61 to facilitate substrate
Use of CK
Heterogeneity in the sn
BHLHE41 Overexpression Alleviates the Malignant Behavior of Colon Cancer Cells Induced by Hypoxia via Modulating HIF
Ginsenoside Rb1 alleviates 3
Synthesis and potent antileukemic activities of 10
Bimatoprost 155206
CD3D
BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c
Aflatoxin Q
ONO
Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1 PMID 35652039
HIF
ZNL
Knockdown of disheveled
Nε
GALNT6 drives lenvatinib resistance in hepatocellular carcinoma through autophagy and cancer
3
HGF 蛋白, Mouse (HEK293, His)
吲哚
Carbocisteine
Hesperetin blocks poxvirus replication with a low tendency to select for drug
UNC5B 蛋白, Rat (HEK293, Fc)
Inhibition of Unc
半乳糖苷酶 1（GLB1）基因
1,2
CD40 蛋白, Cynomolgus (HEK293, His)
Transcriptomics
Salidroside attenuates CoCl2
Trichostatin C 68676
AZA1 (Rac1/Cdc42
N
NSC 233846
Steroidal saponins from Solanum nigrum PMID 16933867
CDC42BPB Human Pre
IL
trans
2
Sulphadoxine d<sub>3</sub>
Evaluation of the toxicity of ISIS 2302, a phosphorothioate oligonucleotide, in a 4
Unbiased Drug Target Prediction Reveals Sensitivity to Ferroptosis Inducers, HDAC and RTK Inhibitors in Melanoma Subtypes PMID 39722169
Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signaling inhibitors by small
ODN24991
Anticancer agent268
HCC
RO
ROC 0929
糖蛋白 Ib 血小板亚基 β（GP1BB）基因
4
SjDX5
GV150013X
Scutellaria salviifolia Benth.提取物 (Scutellaria salviifolia Benth.)
Rho GTPase inhibitor 1
Klf5 Rat Pre
Methyltetrazine
Amplifying X
monoamine oxidase type B (MAO
Tumor suppressor BAP1 suppresses disulfidptosis through the regulation of SLC7A11 and NADPH levels PMID 39266549
共658页
首页
上一页
569
568
567
566
565
564
563
562
561
560
559
下一页
尾页
生物活性分子
ICP证:
粤ICP备2021105330号-3
联系人QQ：9145908
返回首页
RSS更新