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Cellularly active N
Artesunate as an Anti
左旋氨氯地平
A chemical platform for improved induction of human iPSCs PMID 19838168
大麻烯
Plant sterol ester of α
TRX 385
Sorbitol Destroyed Intestinal Microfold Cells (M Cells) Development through Inhibition of PDE4
Anticancer agent64
Verteporfin can Reverse the Paclitaxel Resistance Induced by YAP Over
PXYD4
Non
2
Harmine suppresses homologous recombination repair and inhibits proliferation of hepatoma cells PMID 26382920
AM0466
西伯利亚远志呫吨酮A
Drug
T 盒转录因子 19（TBX19）基因
Unraveling the Obesity
m
SL010110, a lead compound, inhibits gluconeogenesis via SIRT2
LAU159
Anti
AMP 活化蛋白激酶
Comprehensive assessment of estrogenic activities of parabens by in silico approach and in vitro assays PMID 35810903
Microvesicles shed from bortezomib
B7
Sulforaphane Ameliorate Cadmium
N
Anti
PCSK9 蛋白, Mouse (HEK293, His)
Glassy Drug Microneedle Array Design Drug Glass
Taltobulin intermediate
CYD
Etamivan
Sdc2
Trimedoxime
Enecadin
2
Co
A6770
PTC 510
ODN 5328 sodium (ODN 2395 Control sodium)
N
Rapirosiran (ALN
DA398
Gly
Alkyne
VIPAS39 confers ferroptosis resistance in epithelial ovarian cancer through exporting ACSL4 PMID 40088627
Chemical degrader enhances the treatment of androgen receptor
PEG300 25322
Ddc Mouse Pre
Effects of intergenerational transmission of small intestinal bacteria cultured from stunted Bangladeshi children with enteropathy PMID 39554152
1M Tris
LGI1 Human Pre
lysine targeting
4
BAX
tert
NS 9283
Pasireotide
AV
Anti
Biological evaluation of subglutinol a as a novel immunosuppressive agent for inflammation intervention PMID 24900866
Differential Protective Effect of Resveratrol and Its Microbial Metabolites on Intestinal Barrier Dysfunction is Mediated by the AMPK Pathway PMID 36066018
Extracellular vesicle
Nitrosotetracaine
CVT
The ameliorative role of phlorotannin on aflatoxin B1
2
PE
LC20
GRP78 inhibition enhances ATF4
(Rac)
16
hookworms
Deacetylanisomycin (脱乙酰茴香霉素)
Design and in vitro anticancer assessment of a click chemistry
Luteolin alleviates polycystic ovary syndrome in rats by resolving insulin resistance and oxidative stress PMID 33900851
TLE 家族成员 5，转录调节因子（TLE5）基因
Kif18a Rat Pre
CD38 分子（CD38）基因
Chemogenomics for steroid hormone receptors (NR3) PMID 39900826
(±)
Protein Kinase B/Akt1 Phosphorylates Dysbindin
Effect of the TIM
The APEX1/miRNA
Bud31 Rat Pre
Effect of Optimized Concentrations of Basic Fibroblast Growth Factor and Epidermal Growth Factor on Proliferation of Fibroblasts and Expression of Collagen Related to Pelvic Floor Tissue Regeneration PMID 30127219
OPG
[68Ga]Ga/[177Lu]Lu
Exosomal PGE2 from M2 macrophages inhibits neutrophil recruitment and NET formation through lipid mediator class switching in sepsis PMID 37533081
Nanomedicine
Interaction of YAP1 and mTOR promotes bladder cancer progression PMID 31789387
Pharmacological Activation of RXR
antiplasmodium
1
Infection with a newly designed dual fluorescent reporter HIV
Berberine Protects Glomerular Podocytes via Inhibiting Drp1
species
HS 79
BIO5192 327613
4
RNF113A targeted by miR
USP18
Penicillide 55303
Medicarpin 32383
HRD1 inhibits fatty acid oxidation and tumorigenesis by ubiquitinating CPT2 in triple
Effect of chemogenetic actuator drugs on prefrontal cortex
Upregulation of Superenhancer
Long
Metformin rescues Parkinson's disease phenotypes caused by hyperactive mitochondria PMID 33024014
Tol
SIRT5
SK
Modulating the systemic and local adaptive immune response after fracture improves bone regeneration during aging PMID 34998981
Inhibition of visfatin alleviates sepsis
INSL5
VPC
NRG1
11
PCK2 promotes invasion and epithelial
Colistin enhances caspofungin antifungal efficacy against Aspergillus fumigatus by modulating calcium homeostasis and stress responses PMID 40592863
HMGB1/TREM2 positive feedback loop drives the development of radioresistance and immune escape of glioblastoma by regulating TLR4/Akt signaling PMID 39075517
Hydroxyterbuthylazinel
Diflovidazin damages the hematopoietic stem cells to zebrafish embryos via the TLR4/ NF
SR9243 1613028
Neurokinin A(4
N
D
Berberine attenuates pulmonary arterial hypertension via protein phosphatase 2A signaling pathway both in vivo and in vitro PMID 30078229
CDKN2B antisense RNA 1 expression alleviates idiopathic pulmonary fibrosis by functioning as a competing endogenouse RNA through the miR
MicroRNA
Divergent Response to Cannabinoid Receptor Stimulation in High and Low Stress
Siglec
Uridine 5′
Knockdown of IRE1ɑ suppresses metastatic potential of colon cancer cells through inhibiting FN1
Dihydroartemisinin synergistically enhances the cytotoxic effects of oxaliplatin in colon cancer by targeting the PHB2
csi
Synergistic regulation of DACH1 stability by acetylation and deubiquitination promotes colorectal cancer progression PMID 40389405
AGL
PIK3CA(H1047R)
LRTI
Surufatinib
A natural AKT inhibitor swertiamarin targets AKT
TTA
8
Diagnostic value of sialyl
Elucidating the Neuroprotective Mechanism of Geissoschizine Methyl Ether against Parkinson's Disease Inhibition of Ferroptosis Pathway via Network Pharmacology and In Vitro Validation PMID 41048757
Epac1 Inhibits Orbital Fibroblast Activation to Ameliorate Thyroid
CD30/TNFRSF8 蛋白, Human (HEK293, His
Cyhalothrin
Magnolol attenuates depressive
Therapeutic effects and potential mechanism of dehydroevodiamine on N
Lztr1 deficiency contributes to the pathogenesis of dilated cardiomyopathy via RAP1/PI3K/AKT
IRL
MCE
ASN04421891
Ercalcidiol 21343
Z
L 741626
Isobutyric acid promotes colorectal cancer metastasis through activating RACK1 PMID 37519194
Uncovering cellular senescence as a therapeutic target in NF2
MG
Nectin
Quercetin Promote the Chemosensitivity in Organoids Derived from Patients with Breast Cancer PMID 39720358
Glypican
4’
A molecular switch OsWRKY10
Omentin
Angpt2 Mouse Pre
Investigation of Scutellaria Barbata's immunological mechanism against thyroid cancer using network pharmacology and experimental validation PMID 39833432
Ferroptosis involved in sevoflurane
Interleukin 22 Expands Transit
STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma PMID 38508140
JB061
Fusidic Acid Reverses Chemoresistance in Breast Cancer via Targeting DDX6 to Downregulate GSK
The TaCLE24b peptide signaling cascade modulates lateral root development and drought tolerance in wheat PMID 40000659
Pyridoxol 5'
A fully human IgG1 anti
ORP5 promotes tumor metastasis via stabilizing c
Proteolytic Activity of the Paracaspase MALT1 Is Involved in Epithelial Restitution and Mucosal Healing PMID 37108564
NVL
parasitaemia model
ATX
Plasticity of the Cullin
沙美利定盐酸盐
Chlormadinone acetate
氯醛糖
FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway PMID 32021289
Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling PMID 39394530
A novel FFA1 agonist, CPU025, improves glucose
CHRDL2 promotes osteosarcoma cell proliferation and metastasis through the BMP
Withaferin A and Withanolide D Analogues with Dual Heat
ICA1 affects APP processing through the PICK1
chelate
Neurons derived from NeuroD1
FoxJ1 inhibits African swine fever virus replication and viral S273R protein decreases the expression of FoxJ1 to impair its antiviral effect PMID 35513267
Biogenic Selenium Nanoparticles Attenuate Aβ25
Chitosan oligosaccharide
SMYD5
CD81 蛋白, Human (HEK293, Fc)
Pseudane IX
Ctsc Mouse Pre
IDH1 蛋白, Human (HEK293, His, Solution)
Chemotaxis
HIF
ligand efficiency
NRP1
High
Lipid metabolism
NOP agonist 2
6
CD40 and B
Aurora A
Nuclear translocation of PKM2 mediates keratinocyte metabolic reprogramming in psoriasis PMID 37688280
A
Butalamine
Urolithin B (Standard)
Fucoidan ameliorates lipid accumulation, oxidative stress, and NF
Mesenchymal stem cells alleviate idiopathic pneumonia syndrome by modulating T cell function through CCR2
Heneicomycin 66170
HS 38
柚提取物 (Citrus maxima (Burm.) Merr.)
2
骨髓性白血病因子 2（MLF2）基因
2
miR
(+)
A Bioinspired Immunostimulatory System for Inducing Powerful Antitumor Immune Function by Directly Causing Plasma Membrane Rupture PMID 38484186
Glycidyl Palmitate
Auto
MAIDS
Vaccination of full
Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model PMID 25264786
Rosiglitazone
HuGAL
Azacyclohexane
KF
IFNα
Aicda Rat Pre
OCM2 Human Pre
TAS6417/CLN
干扰素α6（IFNA6）基因
Decreased expressions of calcium
Bispecific fibrous glue synergistically boosts vascular normalization and antitumor immunity for advanced renal carcinoma therapy PMID 38581762
Sodium 3
(R,R)
USP11 is involved in the sensitivity of liver cancer cells to ferroptosis and taxanes through the regulation of NRF2 ubiquitin
5
EPB41L3 as a prognostic biomarker suppressing cellular malignancy and correlating with the immune microenvironment in glioma PMID 40674816
R
NSvc4 Encoded by Rice Stripe Virus Targets Host Chloroplasts to Suppress Chloroplast
1M Tris
DNA Methylation Mediates lncRNA2919 Regulation of Hair Follicle Regeneration PMID 36012763
RUNX3 抗体 (YA1141)（RUNX3 Antibody (YA1141)）
sigma
The identification of 2
Oleic acid
Downregulation of O
CDK3/CycE1 Recombinant Human Active Protein Kinase
ALN
BUB1b impairs chemotherapy sensitivity via resistance to ferroptosis in lung adenocarcinoma PMID 39043653
D
Underlying mechanisms of metabolic dysfunction
Characterization of the antinociceptive and anti
THPN
N
Targeting GRP78 enhances the sensitivity of HOS osteosarcoma cells to pyropheophorbide
IGF1 Human Pre
MCM
Tricetin attenuates atherosclerosis by suppressing macrophage ferroptosis via activation of the NRF2 pathway PMID 39442188
Epibatidine
left ventricular
Regulation of Neuroinflammation by Microglial DUBA
Lower micromolar activity of the antifungal imidazoles on the bacterial
The evolution and characterization of influenza A(H7N9) virus under the selective pressure of peramivir PMID 31400550
VIDD
YO
Tyrosine kinase Fyn promotes apoptosis after intracerebral hemorrhage in rats by activating Drp1 signaling PMID 33409551
Gastrodin promotes Alkbh5 nuclear localization and Gclm m6A demethylation to alleviate ferroptosis in ischemic stroke PMID 40839993
Cyclopropane
Design and Synthesis of A
Bone morphogenetic protein 4 ameliorates corneal neovascularization by inhibiting NLRP3 inflammasome activation through the promotion of CBP
Senescent immune cells accumulation promotes brown adipose tissue dysfunction during aging PMID 37268694
Adipose stem cell‑derived exosomes promote high glucose
BRD7 inhibits the Warburg effect and tumor progression through inactivation of HIF1α/LDHA axis in breast cancer PMID 29725006
Pseudolaric Acid B 82508
Alizarin attenuates oxidative stress
间充质同源盒 2（MEOX2）基因
SNHG3 could promote prostate cancer progression through reducing methionine dependence of PCa cells PMID 35123415
Ginsenoside Rb1 Ameliorates Age
TC
Platinum drugs upregulate CXCR4 and PD
3
Serpina3c regulates adipose differentiation via the Wnt/β
Astrocyte
METTL14
Decitabine promotes the differentiation of poorly differentiated gastric cancer cells and enhances the sensitivity of NK cell cytotoxicity via TNF
Halogenated Compounds from Directed Fermentation of Penicillium concentricum, an Endophytic Fungus of the Liverwort Trichocolea tomentella PMID 28409637
YTHDF1
AD288996
Functionalized 3D
ALN 288996
NEK10 Human Pre
A novel Nlrp3 knock
TBS6b
AL
Junenol
Optimizing the PBS1 Decoy System to Confer Resistance to Potyvirus Infection in Arabidopsis and Soybean PMID 32267815
N
Pharmacological properties of a new selective antiprogestagen Org 33628 PMID 7625721
BU
Glycyrrhizic acid improves tacrolimus
Z
Rapid and contrasting effects of rosiglitazone on transient receptor potential TRPM3 and TRPC5 channels PMID 21406603
Novel morpholin
Shen
Postinfarction Hearts Are Protected by Premature Senescent Cardiomyocytes Via GATA 4
Downregulation of lysine
FGFR
CDK4 蛋白, Human (sf9, His, Avi)
Fenbutatin oxide
Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis PMID 39659733
The Ubiquitination and Degradation of SH2B3 Mediated by MEF2A/WWP2 Axis Restores Microglial Homeostasis to Alleviate Cerebral Microvascular Endothelial Cell Injury in Ischemic Stroke PMID 40407948
3
NSC
LY2510924 1088715
PAF
Safety and efficacy of tirofiban as adjunctive therapy for patients with ST
LY117018 TFA
MK
Iron depletion by deferoxamine up
UK
CMTM4 promotes PD
Integrated network pharmacology, bioinformatics, and experiment analysis to decipher the molecular mechanism of Salidroside on Gastric cancer via targeting NCOA4
Jaceosidin 18085
Progranulin inhibits LPS
lncRNA cytoskeleton regulator reduces non‑small cell lung cancer radiosensitivity by downregulating miRNA‑206 and activating prothymosin α PMID 34558643
p
Neutrophil Extracellular Trap Formation Model Induced by Monosodium Urate and Phorbol Myristate Acetate Involvement in MAPK Signaling Pathways PMID 39796001
Liproxstatin
MOB1A regulates glucose deprivation
Elimination of senescent cells by β
COR627
Isoxadifen
NHPI
6
6
Species
polyprenyl phosphate
20
TIMP
mafosfamide
Hesperidin alleviates pulmonary fibrosis by regulating EI24
HDAC6
3
N,N′
IRAK
Oncoproteins E6 and E7 upregulate topoisomerase I to activate the cGAS
Mirdametinib 391210
L
Tyrphostin A 1
Nav1.7 blocker 1 1426336
Glycidyl oleate
(±)14(15)
CD2
Deacetylation of K481 and K484 on Penaeid Shrimp Hemocyanin Is Critical for Antibacterial Activity PMID 35851542
Ethane
Jie Geng Tang reverses cisplatin resistance through the Nrf2 pathway in lung cancer PMID 36971498
MUC5B regulates alterations in the immune microenvironment in nasopharyngeal carcinoma via the Wnt/β
Targeting PLCG2 Suppresses Tumor Progression, Orchestrates the Tumor Immune Microenvironment and Potentiates Immune Checkpoint Blockade Therapy for Colorectal Cancer PMID 39494327
Cyclic AMP
UBE2E2 enhances Snail
Manumycin G
DMPE
Mycophenolate
CRISPR
PBT434 free base (ATH434 free base)
PERK
PL
Cetyltrimethylammonium bromide
competition for absorption
Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression PMID 27750081
A feedforward circuit between KLF5 and lncRNA KPRT4 contributes to basal
SGLT1 inhibition alleviates radiation
AC
阿维巴坦钠水合物 (Standard)
A new inhibitor of the β
Chemical screening links disulfiram with cardiac protection after ischemic injury PMID 37466803
Hat1 Mouse Pre
Sema4d Mouse Pre
A novel peptide 66CTG stabilizes Myc proto
Liquid Nanoparticles for Nanocatalytic Cancer Therapy PMID 37669827
Snakehead vesiculovirus hijacks SH3RF1 for replication via mediating K63
Development of a novel acetyl glucose
4& 039;,7
克林沙星(Standard)
THUMPD3
PU02 313984
2
LONP1 facilitates pulmonary artery smooth muscle cell glycolytic reprogramming by degrading MPC1 in pulmonary hypertension PMID 40332105
5,10,15
Cyclosporin A inhibits CD11a/CD18 adhesion molecules due to inhibition of TNFalpha and IL
1,1& 039;
An antibody against human interleukin
SSTR3 Human Pre
N
N
Trelagliptin impurity2
Icaritin attenuates ischemia
Myosin抑制剂、激活剂、调节剂、 Control、基因
Serum/glucocorticoid
Secukinumab A Review in Psoriatic Arthritis PMID 27299434
PPARγ antagonist attenuates mouse immune
Il27ra Rat Pre
Bis(diphenylphosphino)methane (Methylenebis[diphenylphosphine]，双二苯基膦甲烷)
C16 Ceramide (d18 1(14Z)/16 0)
D. melanogaster
Absorption, metabolism, and excretion of oral testosterone in humans by mass fragmentography PMID 7440707
The therapeutic potential of galectin
USP7
Pyridoxine exerts antioxidant effects in cell model of Alzheimer's disease via the Nrf
Disrupting intracellular redox homeostasis through copper
DC
ABLIM1 Human Pre
DNA polymerase
MALAT1 silencing suppresses prostate cancer progression by upregulating miR
TRIM59 is suppressed by androgen receptor and acts to promote lineage plasticity and treatment
月桂酰肌氨酸钠盐
Sepsis
Verbascoside 61276
山麦冬皂苷B
NVL Human Pre
Chlormadinone acetate
DSPE
Linoleyl palmitate ((6Z,9Z)
Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin
醋酸氯地孕酮
EOS (d18 1/32 0/18 2)
BST2 蛋白, Human (HEK293, His)
Disinfection effect of hexadecyl pyridinium chloride on SARS
Avibactam impurity 1
Canopy Homolog 2 Expression Predicts Poor Prognosis in Hepatocellular Carcinoma with Tumor Hemorrhage PMID 30415246
XF056
hDHODH
4
NKG2C/CD159c 蛋白, Cynomolgus (HEK293, His)
Bafilomycin A1, a specific inhibitor of vacuolar
CSF2
Tri
Methyl jasmonate downregulates expression of proliferating cell nuclear antigen and induces apoptosis in human neuroblastoma cell lines PMID 18525316
rhADAMTS13 reduces oxidative stress by cleaving VWF in ischaemia/reperfusion
Org13011
(S)
Joint inflammation and early degeneration induced by high
Modulating fast skeletal muscle contraction protects skeletal muscle in animal models of Duchenne muscular dystrophy PMID 36995778
iso
STING Facilitates Vascular Calcification via p
富马酸
CD40 蛋白, Canine (HEK293)
A genome
Synthesis and biological evaluation of rebeccamycin analogues modified at the imide moiety PMID 22749423
mmu
Tislelizumab uniquely binds to the CC' loop of PD
NAD+ Metabolism Reprogramming Drives SIRT1
TMX2039
BCL2 相互作用蛋白 3（BNIP3）基因
PD158780
The metabotropic glutamate receptor 4
MEF2A promoter methylation negatively regulates mRNA transcription and affects myoblast physiological function in cattle PMID 40024578
Purification of an iron
Design, synthesis and biological evaluation of novel 2,3
Enhanced Eryptosis Following Exposure to Dolutegravir PMID 27442249
N
Akkermansia muciniphila ameliorates doxorubicin
Symmetrical dimethylarginine a new combined parameter for renal function and extent of coronary artery disease PMID 16481412
Anti
REST contributes to renal fibrosis through inducing mitochondrial energy metabolism imbalance in tubular epithelial cells PMID 40200371
Selective targeting of parallel G
Polyunsaturated fatty acid supplement alleviates depression
The Construction and Application of a New Screening Method for Phosphodiesterase Inhibitors PMID 38785726
KDM6A 抗体 (YA3532)（KDM6A Antibody (YA3532)）
Cd63 Mouse Pre
B7
Iron overload compromises preimplantation mouse embryo development PMID 34481919
Bactofencin A
Astragalus Polysaccharide Attenuates Cisplatin
GJC1 Human Pre
Increasing cellular NAD+ protects hepatocytes against palmitate
MDL
Subcellular Proteome Analysis Reveals Apoptotic Vulnerability of T
洛硝达唑
MICAL1 facilitates pancreatic cancer proliferation, migration, and invasion by activating WNT/β
NEDD4 like E3 ubiquitin protein ligase represses astrocyte activation and aggravates neuroinflammation in mice with depression via paired box 6 ubiquitination PMID 37661017
The bone marrow mesenchymal stem cells derived migrasomes induced by Titania nanotubes surface serve as chemotaxis effect for osteogenesis PMID 40877924
Antibacterial, antibiofilm, and anti
DnaJ 热休克蛋白家族 (Hsp40) 成员 B6（DNAJB6）基因
MCM8 Human Pre
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