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PPFIA4 promotes castration
hDHODH
Targeted inhibition of ACK1 can inhibit the proliferation of hepatocellular carcinoma cells through the PTEN/AKT/mTOR pathway PMID 32162707
N,N′
果胶酯酶
Theacrine
STA
Mitochondria fission accentuates oxidative stress in hyperglycemia
HDAC4 mediated LHPP deacetylation enhances its destabilization and promotes the proliferation and metastasis of nasopharyngeal carcinoma PMID 37023940
Maresin
(Rac)
O
Umedaptanib pegol (RBM
Antitumor effects of IOX1 combined with bevacizumab
Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics PMID 30735910
DCLX069 792946
Vimentin inhibits α
KLF 转录因子 5（KLF5）基因
DP32
L
Quercetagetin alleviates liver fibrosis in non
Low Expression Levels of SLC22A12 Indicates a Poor Prognosis and Progresses Clear Cell Renal Cell Carcinoma PMID 34249694
DKK
白细胞介素 11（IL11）基因
Carazolol
GlcN6P
Chromotropic acid disodium dihydrate 5808
Aerobic exercise decreases chemerin/CMKLR1 in the serum and peripheral metabolic organs of obesity and diabetes rats by increasing PPARγ PMID 30873215
Seizure control by decanoic acid through direct AMPA receptor inhibition PMID 26608744
Hsa_circ_0003159 inhibits gastric cancer progression by regulating miR
Discovery of novel 6,7
具有叉头相关结构域的 TRAF 相互作用蛋白（TIFA）基因
EG
Identification of CCT3 as a prognostic factor and correlates with cell survival and invasion of head and neck squamous cell carcinoma PMID 34505628
Substituent effects of N
SARS
Nesfatin
IGF2BP2 蛋白, Human (T7
4,7
1,3
Phenformin activates ER stress to promote autophagic cell death via NIBAN1 and DDIT4 in oral squamous cell carcinoma independent of AMPK PMID 38719825
Tenidap in rheumatoid arthritis. A 24
LKB1 suppresses growth and promotes the internalization of EGFR through the PIKFYVE lipid kinase PMID 37904985
BIIL
Zanamivir
Transforming growth factor beta
Structural characterization and immunomodulatory activity of an arabinogalactan from Jasminum sambac (L.) Aiton tea processing waste PMID 36841385
AT9283 hydrochloride 896466
red fire ant
Network Pharmacology and Metabolomics Reveal Anti
NVL 蛋白, Human
Methyl diphenyl phosphate
愈创甘油醚 d<sub>5</sub>
扑热息痛
3
Apigenin (Standard)
ZP 10
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells PMID 40210861
N
H
NL101 synergizes with the BCL
LP 8
alpha
Targeting KRAS mutant cancers by preventing signaling transduction in the MAPK pathway PMID 33228976
In
Polyethylene Glycol Loxenatide Accelerates Diabetic Wound Healing by Downregulating Systemic Inflammation and Improving Endothelial Progenitor Cell Functions PMID 40076985
Guggulsterone induces heme oxygenase
Picenadol hydrochloride (LY
dFdC
Mmd
Tec
thiohydantoin derivative
兰伐替尼N
Non
The Halicylindramides, Farnesoid X Receptor Antagonizing Depsipeptides from a Petrosia sp. Marine Sponge Collected in Korea PMID 26821210
Sulukast 98116
DACN(Tos2,6
(±)
The farnesyltransferase β
5
PDGFRA Rat Pre
D
Ablim1 Rat Pre
Biochemical mechanisms of the generation of endogenous long chain ceramide in response to exogenous short chain ceramide in the A549 human lung adenocarcinoma cell line. Role for endogenous ceramide in mediating the action of exogenous ceramide PMID 11815611
Chlorotrianisene
Zafirlukast
Small extracellular vesicles induce resistance to anti
Fasting improves therapeutic response in hepatocellular carcinoma through p53
Polyethylene glycol loxenatide (PEX168) in subjects with renal impairment A pharmacokinetic study PMID 31396983
三(2
MDA
BMS 801576
GPR120 Agonist 1
KOS
Decanoyl
AZD
OGD
NR2B
ATP
CCR3
CDO1 phosphorylation is required for IL
5F
乙酰磺环己脲
CCL24/Eotaxin
1
Foxk2 Enhances Adipogenic Differentiation by Relying on the Transcriptional Activation of Peroxisome Proliferator
Fungal metabolites of (E)
M2 macrophages, but not M1 macrophages, support megakaryopoiesis by upregulating PI3K
MDA
CTSC
11 0 PC
analgesic
JNJ
2
Zuclopenthixol decanoate
N6
Ccn4 Rat Pre
BEA005
glutamatergic
Triene prostaglandins prostaglandin D3 and icosapentaenoic acid as potential antithrombotic substances PMID 230492
Bcl
M3 receptor
ICD
TGF
Osteopontin/OPN 蛋白, Human (HEK293, His)
Nifuroxazide
Paspalinine
TNIK Human Pre
N
CPSF3
PARP
ML402
Cetrimonium
Methocinnamox
Ucenprubart
TRKB(NTRK2) Recombinant Human Active Protein Kinase
磺胺二甲氧嗪
Citric acid triammonium
ACVR2B 蛋白, Human/Cynomolgus (Biotinylated, HEK293, Fc
CA125 蛋白, Human (HEK293, His
Esaprazole 64204
NLRP10 maintains epidermal homeostasis by promoting keratinocyte survival and P63
CC
CYB5R3 Human Pre
GSK878
Mesenchymal stromal cells regulate THP
Niguldipine monohydrochloride
LAIR1 promotes hepatocellular carcinoma cell metastasis and induces M2
RBBP6 maintains glioblastoma stem cells through CPSF3
Bile acids promote the caveolae
ASP 4000
TMX
Aldo
2A/2B Dengue protease substrate
DDC18
ABC34
Compressive Stress and Inflammation Induce Ferroptosis in Periodontal Ligament Cells Through ACSL4 Activation in Orthodontically Induced Inflammatory Root Resorption PMID 40579979
MDX
Anicequol 440368
Flupyrsulfuron
Thyroid Hormone Receptor
D
Tiamulin Fumarate
The carbonic anhydrase IX inhibitor SLC
Effective targeting of PDGFRA
MK
ATXN3 controls DNA replication and transcription by regulating chromatin structure PMID 36971114
Triptolide induces atrophy of myotubes by triggering IRS
Human cytomegalovirus UL36 inhibits IRF3
Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2
Deguelin Restores Paclitaxel Sensitivity in Paclitaxel
Amivantamab 2171511
Targeting NOTCH1
Cytochalasin G
Fibroblast
Temanogrel hydrochloride 957466
Songorine promotes cardiac mitochondrial biogenesis via Nrf2 induction during sepsis PMID 33189984
Synthetic lethality of combined AT
Arctiin attenuated NASH by inhibiting glycolysis and inflammation via FGFR2/CSF1R signaling PMID 40010483
Bruton's Tyrosine Kinase Inhibitors Ibrutinib and Acalabrutinib Counteract Anthracycline Resistance in Cancer Cells Expressing AKR1C3 PMID 33322571
2
1H
HSD17B13
LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells PMID 38607916
WWC1 mutation drives dopamine dysregulation and synaptic imbalance in Tourette's syndrome PMID 40153501
Macrophage Polarization Modulated by Porcine Circovirus Type 2 Facilitates Bacterial Coinfection PMID 34394082
Negative and positive allosteric modulators of the P2X(7) receptor PMID 18071294
SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis PMID 33753739
Enterococcus hirae
瑞卡帕布
Elevated FSP1 protects KRAS
Rhod
Antigen Cross
解草酯
DDX3X/MAVS alleviates doxorubicin‑induced cardiotoxicity by regulating stress granules PMID 40576139
Alteration of intestinal microecology by oral antibiotics promotes oral squamous cell carcinoma development PMID 35803000
Atp2a2 Rat Pre
Targeting ALDH16A1 mediated thioredoxin lysosomal degradation to enhance ferroptosis susceptibility in SMARCA4
1,3
The immunoregulator β
Tetrahedral DNA Nanostructure
Ibrutinib Racemate 936563
Stepwise activation of SARM1 for cell death and axon degeneration revealed by a biosynthetic NMN mimic PMID 39964720
Desuccinylation of TBK1 by SIRT5 regulates inflammatory response of macrophages in sepsis PMID 39673708
Restrictocin (限制性霉素)
Chloride intracellular channel CLIC3 mediates fibroblast cellular senescence by interacting with ERK7 PMID 39809890
sEH
5
GMS
USP28
SMARCA4 regulates the NK
Identification of Cardiac Glycosides as Novel Inhibitors of eIF4A1
Schizandrin A induces the apoptosis and suppresses the proliferation, invasion and migration of gastric cancer cells by activating endoplasmic reticulum stress PMID 34498719
Keratin sulfate
LSD1
Pyrotinib and trastuzumab combination treatment synergistically overcomes HER2 dependency in HER2
Generation of induced pluripotent stem cells without genetic defects by small molecules PMID 25477171
Basic Blue
Effects of derivatives of kahweol and cafestol on the activity of glutathione S
Caylin 2
Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells PMID 30864717
Siglec
RO
ARRB1 Human Pre
HDAC
ULK
TRV
TEFM facilitates uterine corpus endometrial carcinoma progression by activating ROS
HRP
阿比多尔盐酸盐
KRT20 Human Pre
PIM1 promotes hepatic conversion by suppressing reprogramming
Estrogen receptor coregulator binding modulator (ERX
Chikusetsu saponin IVa regulates glucose uptake and fatty acid oxidation implications in antihyperglycemic and hypolipidemic effects PMID 25677570
[Pharmacokinetics of Phosphate Retagliptin Tabletin in Patients with Renal Dysfunction] PMID 29737094
Parathyroid hormone
Tafenoquine Succinate (WR 238605 Succinate，他非诺喹琥珀酸盐)
Snrpg
Naftidrofuryl (Nafronyl)
Sodium stibogluconate is a potent inhibitor of protein tyrosine phosphatases and augments cytokine responses in hemopoietic cell lines PMID 11544330
Naftidrofuryl
HY
A glucose
SMARCD1 is a dual regulator of PD
Protective effect of astragaloside IV against zinc oxide nanoparticles induced human neuroblastoma SH
DSPE
ALK2
Rapamycin inhibits B16 melanoma cell viability invitro and invivo by inducing autophagy and inhibiting the mTOR/p70‑S6k pathway PMID 38385108
Functional
HBF
Sodium phosphate buffer 0.1M, pH 7.2 (磷酸钠缓冲液 0.1M, pH 7.2)
Sodium phosphate buffer 0.1M, pH 7.5 (磷酸钠缓冲液 0.1M, pH 7.5)
Sodium phosphate buffer 0.1M, pH 6.8 (磷酸钠缓冲液 0.1M, pH 6.8)
Scrambled 10Panx (FSVYWAQADR)
EGR4 Human Pre
Pyrroloquinoline quinone ameliorates diabetic cardiomyopathy by inhibiting the pyroptosis signaling pathway in C57BL/6 mice and AC16 cells PMID 34997266
Astragalus polysaccharide restores insulin secretion impaired by lipopolysaccharides through the protein kinase B /mammalian target of rapamycin/glucose transporter 2 pathway PMID 37817130
(Rac)
Tricholopardins A and B, Anti
MCE
RNA
Tnc Rat Pre
Icam5 Rat Pre
MicroRNA
2
Metalaxyl
The Therapeutic Potential of Lactobacillus crispatus for Chronic Endometritis A Comprehensive Clinical Trial and Experimental Investigation PMID 39172215
Nonanal
Macrophage
CCN6 Human Pre
LGLLLRHLRHHSNLLANI
Chick CB9 of type II collagen (Chick cyanogen bromide digested peptide 9)
[Efficacy and safety of divozilimab during 24
Design, Synthesis, and Biological Evaluation of 1
antidiabetes
转录因子 4（TCF4）基因
African swine fever virus pNP419L inhibits type I interferon signaling by blocking ISGF3
Sophora flavescens
ROS inhibitor N
4
Si
Selective N
Mouse and human FcR effector functions PMID 26497511
5,22
Cyclopropylcarboxylic acid
m6A
Maximin 3 634600
p
Prostaglandin D3 71902
1
(D
Animal
S
7
The Nonpeptide Agonist MK
Nifuroxazide 965
Interferon
A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis PMID 28107195
The Modulation of Trehalose Metabolism by 20
Nonanal (正壬醛)
Chick CB12 of type II collagen (Chick cyanogen bromide digested peptide 12)
Urocortin II, human 351999
PH
Gestodene
3
VNPP433
DMP
DL
Cyclosporin C 59787
Pharmacokinetics of orally and intravenously administered riboflavin in healthy humans PMID 8604671
Inhibition of USP7 upregulates USP22 and activates its downstream cancer
Circular RNA UBE2Q2 promotes malignant progression of gastric cancer by regulating signal transducer and activator of transcription 3
细胞周期素 T1（CCNT1）基因
Tenascin/Tnc 蛋白, Human (HEK293, His)
基质金属肽酶 12（Mmp12）基因
D
Analysis of Chlamydomonas thiamin metabolism in vivo reveals riboswitch plasticity PMID 23959877
Chemotherapy
Cullin5 drives experimental asthma exacerbations by modulating alveolar macrophage antiviral immunity PMID 38177117
LDC 000067
cis
1
Anti
雷迪帕韦杂质53 (标准品)
Etoricoxib
TNFRSF11B Human Pre
TAS1R3 Human Pre
ABHD17C Human Pre
TPABr
BMS
A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi
Bnc1 Mouse Pre
AV 4025
ANXA2 promotes chondrocyte differentiation and fracture healing by regulating the phosphorylation of STAT3 and PI3K/AKT signaling pathways PMID 39863030
MPGES
BAY
AMT
SDH
H
RK 20449 trihydrochloride
FC
A LINC00472
Arrb1 Rat Pre
Spinosyn D 17
hCA I
Abra Rat Pre
[Deamino
LSD1
FLT3
KRAS G12D ligand
1,2
Tetradecanoylcarnitine
GR 64349
D
dMeThPmR
BION106
[Results of a phase 1 clinical study of anti
Isonicotinoyl chloride
Sulfur
Inhibition of farnesyltransferase a rational approach to treat cancer? PMID 17518338
C16 Ceramide
C
2
Hyaluronic acid sodium (MW 800kDa)
AGA
N
Brilliant green 633
3′,5′
The tyrosine kinase inhibitor GNF
BDP 581/591 hydrazide
(Rac)
BM
8(E)
(±)
WJM
Mislocalize
Dihydrorhodamine 123 (solution)
Levofloxacin N
Simple and rapid determination of N(6)
Suberoyl bishydroxamic acid activates notch1 signaling and suppresses tumor progression in an animal model of medullary thyroid carcinoma PMID 18563491
L
Tenidap sodium 119784
Ablim1 Mouse Pre
Cathepsin C
Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin)
An updated review on the inhibition of exosome biogenesis, release, and uptake a potential anticancer approach PMID 40499840
(Leu31,Pro34)
Doxpicomine
Role of leukotrienes in exercise
MitoTracker Green FM (solution)
Irampanel hydrochloride (BIIR
MCM3 Human Pre
A Cyclometalated Iridium(III) Complex Exerts High Anticancer Efficacy via Fatty Acid Beta
Gentiopicroside ameliorates glucose and lipid metabolism in T2DM via targeting FGFR1 PMID 38885580
Resveratrol restrains colorectal cancer metastasis by regulating miR
Zafirlukast 107753
Carbadox
Pristane 1921
AU1235
OPA1 线粒体动力蛋白样 GTPase（OPA1）基因
Desvenlafaxine
CP 472295
VEGFR2 Kinase Inhibitor I
Optineurin promotes myogenesis during muscle regeneration in mice by autophagic degradation of GSK3β PMID 35476671
Mucosal vaccination with long
AC710 Mesylate
LS2265
E4F1
3β,5α,6β
Hepatitis B Virus X Protein Upregulates SREBP2 to Modulate Autophagy in Hepatocellular Carcinoma PMID 40476478
TBK1
Y08060
免疫球蛋白重常数伽马 4 (G4m 标记)（IGHG4）基因
Unlocking the potential unveiling tyrphostins with Michael
Prospects of β
Ginkgolic acids and Ginkgo biloba extract inhibit Escherichia coli O157 H7 and Staphylococcus aureus biofilm formation PMID 24457153
Potassium tetraborate tetrahydrate, 99.5% 12045
Low Expression of Selenoprotein S Promotes Osteogenic Differentiation in Bone Marrow Mesenchymal Stromal Cells PMID 40342061
CPSF3 regulates alternative polyadenylation of CNIH2 to promote esophageal squamous cell carcinoma progression PMID 38718887
2
Integrated analysis identifies P4HA2 as a key regulator of STAT1
HSDVHK
Viral infection and spread are inhibited by the polyubiquitination and downregulation of TRPV2 channel by the interferon
Baicalin alleviates lipid accumulation in adipocytes via inducing metabolic reprogramming and targeting Adenosine A1 receptor PMID 40188992
Epigenetic Silencing of BMP6 by the SIN3A
AKT
Protoporphyrin IX and verteporfin potently inhibit SARS
Axonal Transport Defect in Gigaxonin Deficiency Rescued by Tubastatin A PMID 37268847
Evaluation of neuroprotective effect of quercetin with donepezil in scopolamine
Reperfusion of cerebral artery thrombosis by the GPIb
CPSF1 inhibition promotes widespread use of intergenic polyadenylation sites and impairs glycolysis in prostate cancer cells PMID 39847481
Disulfiram
Diphenylmethane skeleton as a multi
HA 9104
The absence of AhR in CD4+ T cells in patients with acute graft
Adipose Tissue
nitrosourea alkylating
Prenylamine lactate (Standard)
GSK 221149A
Anti
Identification and characterization of new impurities in zopiclone tablets by LC
Acetylisoniazid (AcINH，乙酰异烟肼)
6PPD
PNT001
Vitamin K2(35)(Standard)
Guilongwan Ameliorates Experimental Diabetic Foot Ulcer in Rats via the Inhibition of Delta
氨基葡萄糖 (N
Differential effect of the protein synthesis inhibitors puromycin and cycloheximide on vascular smooth muscle cell viability PMID 18322149
FXR
NINL Human Pre
2,6
Long
RUNX1 promotes proliferation and migration in non
Polyvinyl chloride nanoplastics suppress homology
A simple, rapid and sensitive FRET assay for botulinum neurotoxin serotype B detection PMID 25437190
(E)
MST4 attenuates NLRP3 inflammasome
Rab25 is involved in hypospadias via the β1 integrin/EGFR pathway PMID 38401686
Selenoprotein K enhances STING oligomerization to facilitate antiviral response PMID 37023217
ARNT2 Human Pre
ATP2A2 Human Pre
ROS promote hyper
Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission a mechanism for the attenuation of post
4
Biotin
COX
Sphingosine kinase 2 inhibitor ABC294640 displays anti
Tri
ML262
Bax
7
CLR
ARNT Human Pre
Mitogen
Angiogenin (108
AYX 1
B7
(
L
Aurofusarin 13191
Clopidol (WR
舒噻美
Sodium phosphate buffer 0.1M, pH 6.0 (磷酸钠缓冲液 0.1M, pH 6.0)
Sodium phosphate buffer 0.1M, pH 8.0 (磷酸钠缓冲液 0.1M, pH 8.0)
6
tert
TC2
Aff4 Mouse Pre
AFF4 Human Pre
内皮 PAS 结构域蛋白 1（EPAS1）基因
Akt
PPHP
SB1295
Selitrectinib (Standard) (LOXO
Myristinin B/C
3,5
1
Antiproliferative agent
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