最近收录_第476页_生物活性分子
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Chitosan prevents the development of AOM
OAT
Fc gamma RIIIA/CD16a 蛋白, Human (F176V, HEK293, His
MKK6 蛋白, Human (sf9, His
WAY316606
Rho
CSF1R 蛋白, Rhesus Macaque (C378R, HEK293, Fc)
Discovery of electrophilic degraders that exploit SNAr chemistry PMID 39386645
加巴喷丁
Sesquiterpenoids from Pilea cavaleriei subsp. crenata PMID 19700322
Design, synthesis and biological evaluation of novel benzimidazole amidines as potent multi
Sulfamic and succinic acid derivatives of 25
Lubeluzole
Exposure to 6PPD
VT02956
Size
(
Aberrant Reduction of Short
PGAM1 Human Pre
ATF4 destabilizes RET through nonclassical GRP78 inhibition to enhance chemosensitivity to bortezomib in human osteosarcoma PMID 31534554
Synthesis of new ent
Pgam1 Mouse Pre
IFNAR1 蛋白, Mouse (HEK293, His
5'
T
IL
TRAIL R2/TNFRSF10B 蛋白, Human (HEK293, hFc)
Merulidial 68053
EGFR/HER2
Cofilin 抗体 (YA5414)(Cofilin Antibody (YA5414))
PEG4
Initiator cell death event induced by SARS
ATXN3 Human Pre
酰基辅酶 A 氧化酶 1(ACOX1)基因
Amlodipine besylate (Standard)
Bavachin ameliorates cisplatin
Serpin E1 蛋白, Rat (HEK293, Fc)
URB
Spinosyn A aglycone 149560
Antidepressant
IL
GSK2256098 1224887
Decreased plasma concentrations of L
Silencing lncRNA Lfar1 alleviates the classical activation and pyoptosis of macrophage in hepatic fibrosis PMID 32071306
生物素化屋尘螨提取物, 来源粉尘螨
1,6
Design, synthesis and biological evaluation of novel indole
持续病毒应答
Tetrahydrocorticosterone
IACS
Murideoxycholic acid 668
5
Effects of cefetamet (Ro 15
HSP90
Z
c
hsa
Protease
Ataxin
Triggering endogenous Z
DOTA
Synthesis, anti
Targeting Transient Receptor Potential Melastatin
CVT
A
Novel pyrimidine
Arginase activity in a murine macrophage cell line (RAW264.7) stimulated with lipopolysaccharide from Actinobacillus actinomycetemcomitans PMID 16626370
Decamethonium Bromide 541
LOC609612
Ethyl 9(E)
MCE
Artemisic acid (Qing Hao acid,青蒿酸)
ROR1 蛋白, Human (141a.a, HEK293, His)
Prostate cancer exploits BRD9
Design, Synthesis and Biological Evaluation of a Series of Novel Axl Kinase Inhibitors PMID 22247788
Toward drugs for protease
mmu
Discovery of pteridin
BCY17901
Dothiepin 113
Discovery of imidazo[1,5
Lactone Derivatives Produced by a Phaeoacremonium sp., an Endophytic Fungus from Senna spectabilis PMID 28425292
OX40/TNFRSF4 蛋白, Mouse (Biotinylated, HEK293, His
Blood pressure
印防己毒素
Novel c
Dimethyl sulfoxide, meets analytical specification of Ch.P. 67
ZNRF2 is essential for gliomagenesis through orchestrating glycolysis and acts as a promising therapeutic target in glioma PMID 39953597
Design, synthesis and anticancer activity evaluation of novel C14 heterocycle substituted epi
ALternatives To prophylactic Antibiotics for the treatment of Recurrent urinary tract infection in women (ALTAR) study protocol for a multicentre, pragmatic, patient
ROR1 CAR
Pharmacological characterization of hetrombopag, a novel orally active human thrombopoietin receptor agonist PMID 30156363
IL
Diselaginellin B, an Unusual Dimeric Molecule from Selaginella pulvinata, Inhibited Metastasis and Induced Apoptosis of SMMC
Fas Rat Pre
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6
Structure
曲美替尼二甲亚砜
A whole cell assay to measure caspase
JNK1/2/3 抗体 (YA5943)(JNK1/2/3 Antibody (YA5943))
BmeIF4E2 promotes AcMNPV infection in the silkworm, Bombyx mori, by direct interaction PMID 40915822
睡眠压力
fluorinated
RFC
Dasatinib
Beta
RGB097
Marsformoxide B (台湾牛奶菜双氧甾甙 B)
Promising core structure for nuclear receptor ligands design and synthesis of novel estrogen receptor ligands based on diphenylamine skeleton PMID 18760603
AG 370
Milvexian 1802425
PCSK9 Inhibitor, EGF
Synthesis and biological evaluation of Schizandrin derivatives as potential anti
Wilforine 11088
AZ7550
WR
Inhibitory effect of the alkyl side chain of caffeic acid analogues on lipopolysaccharide
OSM 蛋白, Mouse (HEK293, His)
CD6 蛋白, Human (HEK293, Fc)
NAD(P)H
Glycocinnasperimicin D
Cetoniacytone A
Sonepiprazole mesylate (PNU
(
Neferine induces cell growth inhibition and apoptosis via ROS
2,2,2
Thelenotoside B (25
Morphine induces inflammatory responses via both TLR4 and cGAS
Hemocyanin
(±)
Effective enmein
Rabbit Thrombin (兔凝血酶)
Thymotrinan TFA (RGH
Butyrolactone I (Olomoucin)
Orsellinic acid (苔色酸)
Antitumor effects of butyrolactone I, a selective cdc2 kinase inhibitor, on human lung cancer cell lines PMID 9042196
Bepotastine besilate (Standard) (苯磺酸贝托司汀(Standard))
PD
Pentoxyverine citrate 23142
AK963/40708899
黄杨木提取物 (Buxus microphylla S.et Z.var. Sinica Rehd.et Wils.)
Mitochonic acid 5 regulates mitofusin 2 to protect microglia PMID 33510088
Dinitolmide 148
Indoxyl sulfate
Bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF induce oxidative stress and biomacromolecular damage in human granulosa KGN cells PMID 32289607
Protease
Integrin alpha V beta 6 蛋白, Human (HEK293, His)
Antibody
(S,R,S)
Exploring hydroxamic acid inhibitors of HDAC1 and HDAC2 using small molecule tools and molecular or homology modelling PMID 31400937
biotinylated DNA probes
(8Z,11Z,14Z,17Z,20Z)
Anti
aminoglycoside
RIP1 Contributes to Colorectal Cancer Progression and Lymphatic Remodeling in Association With VEGF
FTO inhibited miR
MTHFD2 promotes PD
Interaction of silymarin flavonolignans with organic anion
FTISADTSK
Human Tenascin,suitable for cell culture (人肌腱蛋白,suitable for cell culture)
2
MDM2
Liposomes, new carriers for delivery of genes and anticancer drugs a systematic review PMID 34282743
Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication PMID 25970561
Top Publications Citing MCE Products
INHBE 蛋白, Human (HEK293, Fc)
The potential of melatonin in sepsis
Comprehensive analysis of ubiquitin
NGFR 蛋白, Human (Biotinylated, HEK293, His
Lacidipine 103890
α
L
Liarozole dihydrochloride (R75251 dihydrochloride)
ATXN3L Human Pre
Anti
ROBO1 enhanced esophageal carcinoma cell radioresistance through accelerating G3BP2
Cytosine
GW9508 ameliorates cognitive dysfunction via the external treatment of encephalopathy in Aβ1
Pyrrolidinoindoline alkaloids from Selaginella moellendorfii PMID 19422203
A shot in the dark how parasitic plants find host roots PMID 20424179
Synthesis and anti
Synthesis and anticancer activity of 2,4
7
Targeting the ESCRT
Age
TNF RII/TNFRSF1B 蛋白, Human (HEK293, hFc)
IL
Pharmacology and chemistry of adapalene PMID 9204085
Human induced pluripotent stem cell
MK
Salmeterol
Oxytocin antiparallel dimer TFA
Tomelukast 88107
Acetylvaline
Sulfasalazine‑induced ferroptosis in breast cancer cells is reduced by the inhibitory effect of estrogen receptor on the transferrin receptor PMID 31173262
丝氨酸羧肽酶 1 (Serine Carboxypeptidase 1)
3
Lunsekimig (SAR443765)
(Z)
Novel Ligustrazine
Tetrahydrorhombifoline
(E)
Synergistic Combination of Luteolin and Asiatic Acid on Cervical Cancer In Vitro and In Vivo PMID 36672499
SNIPER(ABL)
(R)
Synthesis, antitumor activity and mechanism of action of novel 1,3
Versimide 30270
IL
Fc gamma RIIIB/CD16b 蛋白, Human (NA2, HEK293, His
Dual
ELQ
TNF RI/TNFRSF1A 蛋白, Human (HEK293, Fc)
Healing Diabetic Ulcers with MoO3
DC
U1 monocytic cells
FBF1 Human Pre
Mutant p53 activates hnRNPA2B1
Indoxyl sulfate
Pentoxyverine citrate (Standard) (Carbetapentane citrate (Standard),枸橼酸喷托维林 (Standard))
EPCR 蛋白, Mouse (HEK293, His)
Core
Il1rl2 Mouse Pre
ATAD2
Prostratin and 12
A novel adamantane thiadiazole derivative induces mitochondria
Influenza type A virus neuraminidase does not play a role in viral entry, replication, assembly, or budding PMID 7815489
RO5185426
Clinical and Mechanistic Characteristics of Current JAK Inhibitors in IBD PMID 33295611
ALCAM/CD166
Sclareol 515
Conversion of nitroheptane to dihydrojasmone PMID 17340535
Apoptotic vesicles from macrophages exacerbate periodontal bone resorption in periodontitis via delivering miR
In vitro antifungal activity of FK463, a new water
CPCGI Alleviates Neural Damage by Modulating Microglial Pyroptosis After Traumatic Brain Injury PMID 40059065
iridoid
Synthesis and biological evaluation of novel triptolide analogues for anticancer activity PMID 20833543
Synthesis and biological evaluation of indeno[1,5]naphthyridines as topoisomerase I (TopI) inhibitors with antiproliferative activity PMID 27017547
Pyrimidine inhibitors synergize with nucleoside analogues to block SARS
Tetrahydrocorticosterone
Adenosine 2'
Discovery of New Nanomolar Selective IRAP Inhibitors PMID 39916550
IL
Discovery of ARD
Doxorubicin hydrochloride 25316
IL
Arabinose 147
BCL2 相互作用杀手(BIK)基因
Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats PMID 36162485
BC 21
Effective encapsulation of proteins into size
Eslicarbazepine acetate 236395
Iopanoic acid 96
PARP7
Novel indole
(24S)
Isobergapten 482
NGFR Protein, Mouse (HEK293, Fc)
KPT
Fc gamma RIIIA/CD16a 蛋白, Human (HEK293, His)
CD3E
Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response PMID 32492431
Protease
IL
Tolerable Levels of Nonclinical Vehicles and Formulations Used in Studies by Multiple Routes in Multiple Species With Notes on Methods to Improve Utility PMID 26755718
ESC1002755
白介素 17 受体 E(IL17RE)基因
Terpineol 8000
NOD/SCID
E
CCM2 Human Pre
1,4
4,4'
NXE0041178 2642079
ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126 PMID 38515383
Methyl heptanoate 106
Zinc
FABP
Bax Inhibitor
1
CD3E
Application of Integrated Drug Screening/Kinome Analysis to Identify Inhibitors of Gemcitabine
Tessaric acid derivatives induce G2/M cell cycle arrest in human solid tumor cell lines PMID 19664930
发热伴血小板减少综合征
IL
Merbromin
5
Cloning of the human homologue of the GABA transporter GAT
Ethyl 2
Synthesis and antitumor activity of novel 2',3'
3
Top Publications Citing MCE Products
Wisteria Floribunda Lectin (WFA)
Evaluation of small
TNF RI/TNFRSF1A 蛋白, Rat (HEK293, His)
2
SKF 95601
Antioxidant agent
VEGF165 蛋白, Human (HEK293)
Fc gamma RIIIA/CD16a 蛋白, Human (HEK293, His
1,4
Cytotoxic and apoptosis
Azintuxizumab vedotin (ABBV
Metformin induces TPC
KAT6A/YAP/TEAD4 pathway modulates osteoclastogenesis by regulating the RANKL/OPG ratio on the compression side during orthodontic tooth movement PMID 39129034
5
Proteomic profiling of the stem cell response to retinoic acid and synthetic retinoid analogues identification of major retinoid
N
Griseusin A
Cefditoren PMID 30000384
Vaspin 蛋白, Human (HEK293, His)
Human IL
(R,S,S)
中风
NGFR Protein, Mouse (HEK293, His)
Rivulariapeptolides 988
Cell metabolomics to study the function mechanism of Cyperus rotundus L. on triple
GLP
Role of endoplasmic reticulum stress in apoptosis induced by HK2 inhibitor and its potential as a new drug combination strategy PMID 35355227
Discovery of TD
AMPK activator 4
ACOD1, rather than itaconate, facilitates p62
Kaempferol
Design, synthesis, and biological evaluation of 4
(R,S,S)
IFNAR1 蛋白, Human (HEK293, Fc)
Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis PMID 30377225
Necrostatin
Discovery of N
Focus on JNJ
DHX9
Genistein 446
1,2
Isolation of Calenduloside E from Achyranthes bidentata Blume and its effects on LPS/D
1,2
1
Synthesis of oxadiazolidinedione derivatives as quisqualic acid analogues and their evaluation at a quisqualate
1,3,6,8
Pde12 Mouse Pre
lower toxicity
N
5,6
C1galt1 Rat Pre
Akr1c1 Rat Pre
Pde11a Rat Pre
Slc1a2 Rat Pre
C1ql1 Mouse Pre
Diproteverine hydrochloride (BRL 40015 hydrochloride)
food and drug administration
Phosphatase PP2A enhances MCL
MSC
Zalutumumab (扎芦木单抗)
Long non
Veronica derwentiana Andrews提取物 (Veronica derwentiana Andrews)
Twist1 Mouse Pre
CDK9 抗体 (YA4790)(CDK9 Antibody (YA4790))
CHO
Camk1g Mouse Pre
Camk1d Mouse Pre
Camk2a Mouse Pre
BDM91270
Dothiepin
Camk2g Mouse Pre
Camk2b Mouse Pre
AKR1C1 Human Pre
KMT2C is a potential biomarker of prognosis and chemotherapy sensitivity in breast cancer PMID 34240274
Period3 modulates the NAD+
Selective MT(2) melatonin receptor antagonist blocks melatonin
Naphthol AS
Proteomic Level Changes on Treatment in MCF
HOOC
Curcumin mitigates the epithelial
Synthesis and antitumor activity evaluation of maleopimaric acid N
IL
L
Amlodipine besylate and amlodipine camsylate prevent cortical neuronal cell death induced by oxidative stress PMID 21988238
Valproic acid
MCA
Glycerol
Nomegestrol acetate (Standard) (醋酸诺美孕酮 (Standard))
Synthesis and Biological Evaluation of C
Cellular FLICE
Galloylalbiflorin 929042
Ansofaxine 916918
1,2
Docetaxal 125354
Rehmapicroside 104056
Edotecarin 174402
Vanutide cridificar 886584
Zenarestat 112733
7
Derquantel 187865
Balhimycin 140932
Tigloside 216590
H
N
Pyrrophenone 341973
Fonadelpar 515138
TNF RII/TNFRSF1B 蛋白, Mouse (HEK293, His)
Covalent modification of Cys
Peptaibolin 219637
Osm Mouse Pre
PIPES dipotassium 108321
Rimonabant 168273
PEG
Antitumor and toxicity study of mitochondria
4
Felezonexor (CBS9106)
Fas Ligand 蛋白, Human (HEK293, N
Early
碱性亮氨酸拉链核因子 1(BLZF1)基因
The mechanoresponsive chromosomal passenger complex sustains furrow ingression under confinement PMID 40693957
Probucol promotes endogenous antioxidants and provides protection against adriamycin
Mechanistic details of the actinobacterial lyase
BQ123, an ETA receptor antagonist, inhibits endothelin
Wy
Preparation and characterization of monoclonal antibodies against porcine gasdermin D protein PMID 38267794
Isorhamnetin 7
A small natural molecule CADPE kills residual colorectal cancer cells by inhibiting key transcription factors and translation initiation factors PMID 33191401
FRAX486, a PAK inhibitor, overcomes ABCB1
4
过氧化物酶 2(PRDX2)基因
Coronavirus M protein promotes mitophagy over virophagy by recruiting PDPK1 to phosphorylate SQSTM1 at T138 PMID 39414765
Menthol Enhances an Antiproliferative Activity of 1alpha,25
Vitamin B1 monophosphate chloride (Standard) (Thiamine monophosphate chloride (Standard))
The regulation of acetylation and stability of HMGA2 via the HBXIP
Pharmaceutical excipients
Combined inhibition of EZH2 and the autotaxin
VU0404251
VU0238441
RO5203648
VU0240382
8
VU0155094 (ML397)
RO4988546
LY3154207
VU0418506
Hygric acid 475
HPRG 蛋白, Rat (HEK293, His)
VU0285683
VU0364289
Emodin alleviates lung ischemia
VU0506013
LY2066948
VU6001376
VU0409106
AS1892802
RO7185876
VU6016235
VU0090157
VU0029767
VU0359516
Gastrin(1
VU6019650
VU0415374
VU0483605
ARHGAP4 Human Pre
PTH2R激动剂、基因
CAMK2N1 Human Pre
CDK2AP2 Human Pre
Osm Rat Pre
(±)
CDK2/CycA2 Recombinant Human Active Protein Kinase
CDK3/CycE1 Recombinant Human Active Protein Kinase
The antinociceptive and anti
C1qtnf1 Mouse Pre
Transient inhibition of rDNA transcription in donor cells improves ribosome biogenesis and preimplantation development of embryos derived from somatic cell nuclear transfer PMID 32323360
Lodapolimab 2118349
Puromycin
Metabolic perturbation of an essential pathway evaluation of a glycine precursor of coenzyme A PMID 23550886
Discovery of BC
Chitinase, Streptomyces griseus 9001
Bay 65
3
Zalutumumab (powder)
催乳素(PRL)基因
Heliotropium amplexicaule Vahl提取物 (Heliotropium amplexicaule Vahl)
Rheb inhibitor NR1
C1galt1c1 Mouse Pre
C1GALT1C1 Human Pre
Isolation of a tarantula toxin specific for a class of proton
IL
CDK1/CycE1 Recombinant Human Active Protein Kinase
1
CKI
(±)
凝血因子 XI(F11)基因
Etofylline 519
Catalpol regulates apoptosis and proliferation of endothelial cell via activating HIF
裂解荧光素酶互补法
Synthesis and evaluation of chalcone analogues containing a 4
Neurotransmitter imbalance and amygdala synaptic plasticity in lumbar disc herniation
CD47 分子(CD47)基因
L
Erucamide 112
BKN1
CD161/KLRB1
Erythromycylamine
SSR180711 hydrochloride
Slc1a2 Mouse Pre
GLT1D1 Human Pre
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