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KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA PMID 35799276
5
补体 C3（C3）基因
Amlodipine
GPHA2 蛋白, Human (HEK293, His)
TFE3
Serum Albumin/ALB 蛋白, Human (HEK293, His
C1QTNF12 Human Pre
CDK12
Noncovalent CDK12/13 dual inhibitors
Activation of GABA receptor attenuates intestinal inflammation by modulating enteric glial cells function through inhibiting NF
Biochanin A ameliorated oleate
BMS270394
NKX3.1 抗体 (YA4990)（NKX3.1 Antibody (YA4990)）
Herpes virus entry mediator costimulation signaling enhances CAR
JAK inhibition ameliorates bone destruction by simultaneously targeting mature osteoclasts and their precursors PMID 36869390
(S)
Anti
Atxn3 Rat Pre
Miransertib (ARQ
Instability of calcium channel antagonists during sample preparation for LC
Cl
Milnacipran affects mouse impulsive, aggressive, and depressive
LILRA3/CD85e/ILT6 蛋白, Human (HEK293, His
Anti
Clorprenaline 3811
Terodiline hydrochloride
登革病毒衣壳蛋白 (Dengue virus Capsid Proteins)
Design, synthesis and biological evaluation of novel chroman derivatives as non
6
P
2
Integrin alpha V beta 6 蛋白, Rhesus Macaque (HEK293, His)
Zofenoprilat arginine 81872
ASK1 ligand 1 3064087
Integrated analysis of single
NP10679 2914889
Monosodium phosphate, for cell culture
R
MCE
S
fragment
Glucocorticoid receptor agonist
Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/NRF2 pathway PMID 36823108
The novel IMPDH inhibitor VX
(R)
Plasticizer acetyl triethyl citrate (ATEC) induces lipogenesis and obesity PMID 38086441
CGP 20712 A (CGP 20712 mesylate)
Amyloid 17
Tazobactam
Comparative flavor profile analysis of four different varieties of Boletus mushrooms by instrumental and sensory techniques PMID 32846567
β
PVR/CD155 蛋白, Human (Biotinylated, HEK293, His
Preisocalamendiol 25645
BDP8900
LJI308
CCL9/10/MIP
Antiinflammatory and analgesic activities of Thesium chinense Turcz extracts and its major flavonoids, kaempferol and kaempferol
Cytostatin sodium 457070
SRT2104 attenuates diabetes
Os30
OSM Human Pre
NAD(P)H
GAS2L2
Azacyclonol 115
Human IL
Nazartinib mesylate (EGF816 mesylate)
15
Ondansetron 99614
Protective effects of dioscin against isoproterenol
acute
STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis PMID 35600336
CT 52923
Licarbazepine
Ganglioside GT1b
Licarbazepine
1
Licarbazepine
1
Sulfisomidin 515
Fenirofibrate
7
D
N
Usmarapride free base (SUVN
2
Melatonin inhibits salivary gland epithelial cell ferroptosis via the NRF2/HO
Fissistigine A
ILC3s promote intestinal tuft cell hyperplasia and anthelmintic immunity through RANK signaling PMID 40378237
c
Il17ra
Iopanoic acid (Standard) (碘番酸(Standard))
PROTAC BRD4 Degrader
Discovery and Synthesis of Heterobifunctional Degraders of Rearranged during Transfection (RET) Kinase PMID 39437163
肌肉生长抑制素（MSTN）基因
Identification and Characterization of the Neisseria gonorrhoeae MscS
YY1
CDK5 promotes apoptosis and attenuates chemoresistance in gastric cancer via E2F1 signaling PMID 37990321
Interaction of two novel 14
TrkB 蛋白, Canine (HEK293, His)
Palladium
The in vitro pharmacological profile of TD
Aerobic glycolysis enhances HBx
LAMC1
FGF
Non
IL
enantio
Design, synthesis and screening of benzimidazole containing compounds with methoxylated aryl radicals as cytotoxic molecules on (HCT
Cationic trypsin 蛋白, Dog (His
COX
转化生长因子 β 受体 2（TGFBR2）基因
CypA/TAF15/STAT5A/miR
Inhibition of protein kinase C protects against paraoxon
SC 51089
Quercetin ameliorates oxidative stress, inflammation and apoptosis in the heart of streptozotocin
rat
TCPOBOP
Antimicrobial peptide CRAMP/LL
Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension PMID 21988216
GPHA2 蛋白, Human (HEK293, Fc)
Inhibition of CISD1 attenuates cisplatin
PIK3C3
Guizhi Fuling Capsule Exhibits Antidysmenorrhea Activity by Inhibition of Cyclooxygenase Activity PMID 32595743
HA
Cytochalasin H 53760
CD6 蛋白, Mouse (HEK293, His)
A new coruleoellagic acid derivative from stems of Rhodamnia dumetorum PMID 29073789
Targeting the up
7
Isoxazol
Synthesis, transformation and biological evaluation of 2,3
L
MHI
Enhanced antitumor efficacy of folate
IP3RCYT
A low
UCSF678
Thermopsidine 492
Dehydrocostus Lactone 477
Eif2ak1 Rat Pre
Epigenetic regulation of ferroptosis by H2B monoubiquitination and p53 PMID 31267712
A novel 450
((Benzyloxy)carbonyl)
HIV
Inhibition of sphingolipid metabolism in osteosarcoma protects against CD151
Palladium hydroxide on activated carbon(20%)(wetted with ca. 55% Water) 12135
Development of a versatile system for evaluating the target protein degradation activity of novel ubiquitin ligases utilizing existing PROTACs PMID 39864384
PRESENCE OF CITRININ IN GRAINS AND ITS POSSIBLE HEALTH EFFECTS PMID 28480413
KAD
Angiotensin converting enzyme
Genetically Engineered Membrane
Characterization of selective and potent PI3Kδ inhibitor (PI3KDIN
(Rac)
IgG1 monoclonal antibody
Astrocytic HSP60 Deletion Induced Astrocyte Senescence and Inhibited Neuroregeneration via Modulating the S1P/Truncated
COR659
METTL3
N
Top Publications Citing MCE Products
Boosting mRNA cancer vaccine efficacy via targeting Irg1 on macrophages in lymph nodes PMID 40521193
Lactic Acid Fermentation Is Required for NLRP3 Inflammasome Activation PMID 33854503
macropinocytosis inhibitor
Child Health
Valerenic acid 3569
14
Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia PMID 32545904
Frajunolides E
骨形态发生蛋白 11 (BMP
RET ligand
Cblb
PEG
Structure
Pim
nAChR
Bemfivastatin 805241
NF
A Novel Single
Cav2 Rat Pre
p24 蛋白, HIV
The effects of quinacrine, proglumide, and pentoxifylline on seizure activity, cognitive deficit, and oxidative stress in rat lithium
Gunagratinib 2211082
Bulumtatug 2862919
Delaying pyroptosis with an AI
Rintodestrant 2088518
CYM51010 1069498
Prolyl Hydroxylase inhibitor 1
SAR405838 1303607
2,2,6
FX5 as a non
Seniprutug
MMAB Human Pre
Dezamizumab (GSK 2398852，迪扎米珠单抗)
Raxibacumab (ABthrax，雷昔库单抗)
Alsevalimab (艾司沃利单抗)
Basiliximab (CHI 621，巴利昔单抗)
Tepilukimig
Tosatoxumab (KBSA301，托萨托舒单抗)
Rontalizumab (RhuMab IFNalpha，隆利组单抗)
Tacatuzumab (替组单抗)
Tucotuzumab (西莫白介素单抗)
alpha
Raxibacumab potential role in the treatment of inhalational anthrax PMID 24812521
ASBT
IMM20324
贝洛托舒单抗
Protocol for the isolation of GFP
IPH5201
Vofatamab (B
Estriol 3
KHK2823
Usilnetug
Elsilimomab (B
Firivumab (CT
Lemalesomab (IMMU
GSK2831781
Keliximab (SB
Talizumab (TNX 901，他利珠单抗)
Megestrol
AP 611074
GSK2618960
hPTH(3
Sulesomab (硫索单抗)
Anti
Anti
RO5323441 (TB
The regulatory effect of CoL10A1 to the intracranial vascular invasion and cell proliferation in breast cancer via EMT pathway PMID 40169690
硫酸化蓝肽
Anti
Natural Yellow18
Anti
Azetidine
HER2
Nicotinamide
Protein probes to visualize sphingomyelin and ceramide phosphoethanolamine PMID 30194925
MEK1 activation enhances the ex vivo proliferation of haematopoietic stem/progenitor cell PMID 34855220
Riboflavin deficiency induces a significant change in proteomic profiles in HepG2 cells PMID 28367977
Aqueous extract of Phellinus igniarius ameliorates hyperuricemia and renal injury in adenine/potassium oxonate
1Z105
cartilage
L
9& 039;& 039;
The IRF2
RKI
X
Moscatilin from the orchid Dendrobrium loddigesii is a potential anticancer agent PMID 14628431
TRAIL R2/TNFRSF10B 蛋白, Cynomolgus (HEK293, His)
ROR1 蛋白, Human (113a.a, HEK293, His)
N
Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway PMID 33795638
转录因子 AP
Methoxsalen 298
Type
CYP1B1
Gd
ABCB1 and ABCG2 restricts the efficacy of gedatolisib (PF
FORCE platform overcomes barriers of oligonucleotide delivery to muscle and corrects myotonic dystrophy features in preclinical models PMID 39827287
A phase I trial of ISIS 2503, an antisense inhibitor of H
Nitrosonisoldipine is a selective inhibitor of inflammatory caspases and protects against pyroptosis and related septic shock PMID 33454984
creatinine
Novel thiosemicarbazone derivatives containing indole fragment as potent and selective anticancer agent PMID 31614257
Target Ligand Separation and Identification of Isoforsythiaside as a Histone Lysine
DDC 蛋白, Human
Sacchathridine A, a prostaglandin release inhibitor from Saccharothrix sp PMID 23581596
Clusterin negatively modulates mechanical stress
Pharmacological profile of FR260330, a novel orally active inducible nitric oxide synthase inhibitor PMID 15713431
Quercetin Induces Apoptosis via Downregulation of Vascular Endothelial Growth Factor/Akt Signaling Pathway in Acute Myeloid Leukemia Cells PMID 33362534
LRP
5α
Glyphosate
DNAM
oligoasthenospermia
BB
UNC569
MEC/CCL28 蛋白, Mouse
Paclitaxel octadecanedioate
The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity
Cycloguanil hydrochloride 152
IL
Hinokitiol inhibits cell growth through induction of S
4E2RCat 432499
Cyclobutane quisqualic acid analogues as selective mGluR5a metabotropic glutamic acid receptor ligands PMID 10229632
Cycloheximide inhibits neurotoxic responses induced by kainic acid in mice PMID 12788213
Il17re Mouse Pre
0990CL
Distribution and Pharmacokinetic Characteristics of Cordycepin in Rat Investigated by UHPLC
PP487
Structure
Melatonin Synergizes With Mesenchymal Stromal Cells Attenuates Chronic Allograft Vasculopathy PMID 33995416
Mutations in OSBPL2 cause hearing loss associated with primary cilia defects via sonic hedgehog signaling PMID 35041619
The Stability
The effect of doxycycline
EC359 2012591
5'
P53/NRF2 mediates SIRT1's protective effect on diabetic nephropathy PMID 30959066
CD43 抗体 (YA3822)（CD43 Antibody (YA3822)）
Thioquinapiperifil 220060
Identification of JTP
Three alternative splicing variants of Loquacious play different roles in miRNA
Cyclin
鱼子兰提取物 (Chloranthus erectus (Buchanan
Class I antiarrhythmic agents quinidine, procainamide and N
Synthesis and evaluation of N
IDO1 inhibitors block septic cytokine storm by suppressing the IDO1
乙酸钠三水合物,医药级,美国药典(USP)级
Antibody
Vascular oxidative stress causes neutrophil arrest in brain capillaries, leading to decreased cerebral blood flow and contributing to memory impairment in a mouse model of Alzheimer’s disease PMID 36824768
ATM inhibition enhance immunotherapy by activating STING signaling and augmenting MHC Class I PMID 39033176
The Obg
Ginsenoside Rg1 ameliorates cerebral ischemia
DSPE
Absorption, distribution, metabolism and excretion of [14C]ebastine after a single administration in rats PMID 7912071
Serpin H1 蛋白, Human (HEK293, His)
Down
Syntabulin regulates neuronal excitation/inhibition balance and epileptic seizures by transporting syntaxin 1B PMID 37349285
Eleven
STAMBPL1/TRIM21 Balances AXL Stability Impacting Mesenchymal Phenotype and Immune Response in KIRC PMID 39527690
Simultaneous determination of 11 oral targeted antineoplastic drugs and 2 active metabolites by LC
Inhibition of GSDMD
F11R Human Pre
Lauric
Clopyralid 1702
Tangzu granule alleviate neuroinflammation in diabetic peripheral neuropathy by suppressing pyroptosis through P2X7R /NLRP3 signaling pathway PMID 39251151
1,2
Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase PMID 9651169
Melatonin promotes the restoration of bone defects via enhancement of miR
Triptolide
BIX
Kallikrein
Potassium molybdate blocks APN
An Automated Organoid Platform with Inter
E. Coli LPS
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editors PMID 38409275
Pectolyase Y
Zimberelimab First Approval PMID 34709602
Microbial and genetic
CTLA
DNSCl
Eriodictyol (Huazhongilexone，圣草酚)
Human serum paraoxonase
1
SPSB2
Inhibition of BCL
EthD
hsa
Acox1 Mouse Pre
Skp2 a dream target in the coming age of cancer therapy PMID 24526126
Allyl heptanoate 142
ICOS 蛋白, Rhesus macaque (HEK293,Fc)
Antiproliferative Activity and Potential Mechanism of Marine
CP
A high
Calcium influx inducer compound
The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome in hepatocellular carcinoma PMID 33960270
Cularine 479
Atypical Gasdermin D and Mixed Lineage Kinase Domain
(D
MCE
Top Publications Citing MCE Products
Mutagenic Impurity of Tenofovir Disoproxil
and FGFR4
Tris[3
Deacetylsclerotiorin 34696
Azide
Top Publications Citing MCE Products
Brominated Flame Retardants Exposure Promotes the Formation of Atherosclerotic Plaque in Aortic Roots of ApoE
D
Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design
Alpha
Novel partially reversible NDM
Evaluation of antioxidant activity of isoferulic acid in vitro PMID 21941899
Biopharmaceutic Profiling of Salts to Improve Absorption of Poorly Soluble Basic Drugs PMID 27637320
Urolithin B suppresses osteoclastogenesis via inhibiting RANKL
TBA
ddUTP (锂盐)
Zebrafish maoc1 Attenuates Spring Viremia of Carp Virus Propagation by Promoting Autophagy
?Pancreatic Cancer
Blunting TRPML1 channels protects myocardial ischemia/reperfusion injury by restoring impaired cardiomyocyte autophagy PMID 35389129
维甲酸 X 受体 β（RXRB）基因
Boc
Harmicines
Human umbilical cord
Hypoxia
METTL3 promotes human amniotic epithelial stem cells differentiation into insulin
7
RISC 蛋白, Mouse (HEK293, His)
A
Gemfibrozil inhibits CYP2C8
BAY
3’
N
Catalpol suppresses osteoclastogenesis and attenuates osteoclast
CGP 20712 A (Standard) (CGP 20712 mesylate (Standard))
Olmutinib hydrochloride (HM61713 hydrochloride)
Evaluation of Zika virus DNA vaccines based on NS1 and domain III of E PMID 36274487
DNAM
Melphalan Recent insights on synthetic, analytical and medicinal aspects PMID 35665692
溶酶体细胞器复合物 1 亚基 6 的生物发生（BLOC1S6）基因
Insights into the medicinal chemistry of heterocycles integrated with a pyrazolo[1,5
Synthesis, activity and docking studies of phenylpyrimidine
S
Hexacosanoic acid
PRL
UBE2T mediates SORBS3 ubiquitination to enhance IL
MCE
4
ICOS 蛋白, Human (HEK293, Fc)
Total synthesis and absolute stereochemistry of pentenocin B, a novel interleukin
NO2
Identification of high
ITIH3 蛋白, Human (HEK293, His)
(Rac)
Enhanced ZBTB10 expression induced by betulinic acid inhibits gastric cancer progression by inactivating the ARRDC3/ITGB4/PI3K/AKT pathway PMID 39873948
Lactate
神经生长因子受体 (Nerve Growth Factor Receptor (NGFR/CD271))
DHODH
IACS
溶质载体家族 2 成员 2（SLC2A2）基因
ACOX1 Human Pre
Aminophylline 317
O
IDR
Nicotinamide mononucleotide enhances porcine sperm quality by activating the SIRT3
TCPOBOP (Standard)
BIK Human Pre
重组蛋白 (细胞因子 生长因子 趋化因子)
Evaluation of the antiproliferative activity of 106 marine microbial metabolites against human lung cancer cells and potential antiproliferative mechanism of purpuride G PMID 33691166
1
Picankibart
Protective and Anti
BMPR
Synthesis and Antileukemic Activities of Piperlongumine and HDAC Inhibitor Hybrids against Acute Myeloid Leukemia Cells PMID 27505848
FGFR
3
Furobufen 38873
JNJ
Cadazolid
Plasma membrane
JNK3 inhibitor
Trypsin
VEGFR
PRL
Synthesis and in vitro anticancer evaluation of novel flavonoid
Agarase 37288
Protein expression of nucleolar protein 12 in the retina and its implication in protection of retina from UV irradiation damage PMID 38467618
MCE
Top Publications Citing MCE Products
CCR2+ Macrophages Promote Orthodontic Tooth Movement and Alveolar Bone Remodeling PMID 35185928
端粒重复结合因子 1（TERF1）基因
F
Methyltetrazine
MEDI
DAG peptide
N
M6903
Chemotherapy
Design, synthesis, and antiviral activity of alpha
BChE/MAO
RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre
DNAM
Thienopyridines nitric oxide synthase inhibitors with potent in vivo activity PMID 11327581
GW 4869
Quinic acid derivatives from Pimpinella brachycarpa exert anti
A brain
P
Anxa8
Sesamin Activates Skeletal Muscle FNDC5 Expression and Increases Irisin Secretion via the SIRT1 Signaling Pathway PMID 35708276
Inhibition of proteolytic and ATPase activities of the proteasome by the BTK inhibitor CGI
Label
Identification and evaluation of Nordihydroguaiaretic acid (NDGA) as an active traditional Chinese medicine compound inhibiting the 3C
ACE2 deficiency inhibits thoracic aortic dissection by enhancing SIRT3 mediated inhibition of inflammation and VSCMs phenotypic switch PMID 39300372
Isofludelone 691868
含 SH3 结构域的 GRB2 样、嗜内源性蛋白 B1（SH3GLB1）基因
Rilpivirine
Design, synthesis and biological evaluation of 6
VU6036720 hydrochloride
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy PMID 37751743
FRAX
Cinerubin A 34044
Chromane helicity rule
Degradation by Design New Cyclin K Degraders from Old CDK Inhibitors PMID 38193430
3,5
alpha
Selenoprotein S regulates tumorigenesis of clear cell renal cell carcinoma through AKT/ GSK3β/NF
Targeting ELOVL6 to disrupt c
Proteome Analysis in PAM Cells Reveals That African Swine Fever Virus Can Regulate the Level of Intracellular Polyamines to Facilitate Its Own Replication through ARG1 PMID 34206713
JNJ
Selective Protein Degradation through Tetrazine Ligation of Genetically Incorporated Unnatural Amino Acids PMID 39221720
Vasorelaxant activity of diterpenes from Croton zambesicus and synthetic trachylobanes and their structure
Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo[4,3
HucMSCs
β
NAMPT degrader 1
BMPR
Anti
On the use of electron capture rate constants to describe electron capture dissociation mass spectrometry of peptides PMID 26307726
Establishment and Identification of a CiPSC Lineage Reprogrammed from FSP
MMP
Natriuretic peptide receptor a promotes gastric malignancy through angiogenesis process PMID 34671022
Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage PMID 39080649
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